☆ 4.7 Article

Bifidobacterium bifidum FJSWX19M5 alleviated 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced chronic colitis by mitigating gut barrier injury and increasing regulatory T cells

FOOD & FUNCTION (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Characteristics of an In Vitro Mesenteric Lymph Node Cell Suspension Model and Its Possible Association with In Vivo Functional Evaluation

Saisai Feng et al.

Summary: This study investigated the immune-responsive patterns of gut microbes using an in vitro MLN model and compared the functional differences between different response patterns in an in vivo TNBS-challenge model. The results showed that different strains of gut microbes evoke immune responses in different ways in vitro and that a mixture of two strong immunogenic strains increases mortality in mice. Further research is needed to determine the underlying mechanisms.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of the gut microbiota and relief from chronic constipation

Luyao Wang et al.

Summary: By using Bifidobacterium bifidum (B. bifidum) CCFM16 treatment, chronic constipation can be effectively relieved by regulating the gut microbiota and short-chain fatty acid metabolism.

FOOD & FUNCTION (2022)

添加到收藏夹

Article Nutrition & Dietetics

A. muciniphila Supplementation in Mice during Pregnancy and Lactation Affects the Maternal Intestinal Microenvironment

Yuli Qi et al.

Summary: This study investigated the impact of Akkermansia muciniphila (A. muciniphila) supplementation during pregnancy and lactation on maternal and offspring health. The results showed that dams fed with A. muciniphila had enhanced intestinal barrier, altered gut microbiota composition and diversity, and significant enrichment of A. muciniphila and Ruminococcus_1 in offspring. However, fecal metabolites only changed slightly in the A. muciniphila group, and the abundance of A. muciniphila in the fecal microbiota of offspring did not significantly increase. The fecal metabolic profile of three-week-old offspring mice fed with A. muciniphila was significantly changed. These findings suggest that A. muciniphila supplementation during pregnancy and lactation is safe and may have a more beneficial effect on dams.

NUTRIENTS (2022)

添加到收藏夹

Review Medicine, General & Internal

Management of Crohn Disease A Review

Kelly Cushing et al.

Summary: Crohn disease is a chronic gastrointestinal inflammatory disease that requires early and effective control of inflammation. Treatment options include medication, surgery, and vaccination for infection prevention. Physicians should consider disease severity, patient risk stratification, age, and other clinical factors when determining the best treatment strategy.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Agriculture, Multidisciplinary

Bifidobacterium longum Ameliorates Dextran Sulfate Sodium-Induced Colitis by Producing Conjugated Linoleic Acid, Protecting Intestinal Mechanical Barrier, Restoring Unbalanced Gut Microbiota, and Regulating the Toll-Like Receptor-4/Nuclear Factor-κB Signaling Pathway

Yang Chen et al.

Summary: Bifidobacterium longum CCFM681 alleviated colitis by protecting the intestinal mechanical barrier, modulating gut microbiota, inhibiting the TLR4/NF-kappa B pathway, and increasing colonic CLA concentrations. The effectiveness of relieving colitis showed a significantly positive correlation with CLA concentrations.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

添加到收藏夹

Article Microbiology

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

Se-Hoon Lee et al.

Summary: Specific strains of Bifidobacterium bifidum can reduce tumor burden synergistically with PD-1 blockade or oxaliplatin treatment by eliciting an antitumor host immune response, indicating their potential therapeutic use.

NATURE MICROBIOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Microbial and metabolic features associated with outcome of infliximab therapy in pediatric Crohn's disease

Yizhong Wang et al.

Summary: The study revealed that pediatric CD patients have gut microbial dysbiosis and altered metabolism after IFX therapy, which is related to treatment outcomes. The effects of IFX treatment may be mediated by enriching bacteria taxa that produce SCFAs and BSH, thereby inhibiting inflammation and restoring bile acid metabolism. Some fecal bacteria and metabolites may serve as predictors of IFX therapy outcomes for pediatric CD patients.

GUT MICROBES (2021)

添加到收藏夹

Article Nutrition & Dietetics

Soluble Fraction from Lysate of a High Concentration Multi-Strain Probiotic Formulation Inhibits TGF-β1-Induced Intestinal Fibrosis on CCD-18Co Cells

Francesca Lombardi et al.

Summary: This study explores the anti-fibrotic impact of two high concentration multi-strain probiotic formulations on TGF-beta 1-activated human intestinal colonic myofibroblast CCD-18Co. The results suggest that the soluble fraction of Vivomixx(R) formulation, but not VSL#3(R), can antagonize the pro-fibrotic effects of TGF-beta 1 on CCD-18Co cells, preventing all cellular and molecular parameters related to fibrotic phenotype. The differences observed between the two probiotics used in the fibrosis model may be due to the different number of strains in different proportions.

NUTRIENTS (2021)

添加到收藏夹

Review Immunology

Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids

Chang H. Kim

Summary: Dietary fiber metabolites, particularly short-chain fatty acids, play crucial roles in maintaining immune system balance, regulating host metabolism, intestinal functions, and immunity system.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Mechanisms and regulation of IL-22-mediated intestinal epithelial homeostasis and repair

Lori Patnaude et al.

Summary: The study found that IL-22 promotes expansion and proliferation of intestinal epithelial stem cells, as well as production of anti-microbial peptides. Additionally, IL-22 alters the composition of the mucus layer. However, the IL-22-associated epithelial phenotype differs in the presence of butyrate and immune cells.

LIFE SCIENCES (2021)

添加到收藏夹

Article Food Science & Technology

The effect of multispecies probiotics on cognitive reactivity to sad mood in patients with Crohn's disease

Lipei Wu et al.

Summary: This study evaluated the impact of probiotics on cognitive reactivity to sad mood in patients with Crohn's disease through a crossover experiment. The results indicated that probiotics have the tendency to improve cognitive reactivity to sad mood in these patients, but the effect may vary at different treatment stages.

JOURNAL OF FUNCTIONAL FOODS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Probiotic Lactobacilli Isolated from Kefir Promote Down-Regulation of Inflammatory Lamina Propria T Cells from Patients with Active IBD

Renata Curciarello et al.

Summary: This study found that Lactobacillus kefiri has immunomodulatory effects on intestinal T cells from patients with IBD, reducing inflammation and increasing the frequency of regulatory T cells.

FRONTIERS IN PHARMACOLOGY (2021)

添加到收藏夹

Article Cell Biology

Mitochondrial transplantation in cardiomyocytes: foundation, methods, and outcomes

Paria Ali Pour et al.

Summary: Mitochondrial transplantation is a novel cellular biotherapy that shows promise in alleviating mitochondrial damage and dysfunction, and potentially improving outcomes of various diseases related to mitochondrial function. By transferring mitochondria from different sources into cells, it has been shown to positively modulate bioenergetics and improve disease outcomes.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2021)

添加到收藏夹

Article Microbiology

A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1

Wei Li et al.

Summary: Bile acids regulate immune balance by affecting T cell differentiation, with isoalloLCA promoting T-reg cell differentiation through chromatin structure changes; gut bacteria capable of producing isoalloLCA belong to common human gut bacterial phylum Bacteroidetes, and NR4A1 is essential for isoalloLCA's effects on T-reg cells; significantly reduced levels of isoalloLCA in patients with inflammatory bowel diseases suggest a critical role for isoalloLCA and its bacterial producers in maintaining immune homeostasis in humans.

CELL HOST & MICROBE (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function but Critical for Effective Mucosal Repair

Wei-Ting Kuo et al.

Summary: The study found that ZO-1 expression was reduced in biopsy specimens from patients with inflammatory bowel disease. Despite mildly increased intestinal permeability, ZO-1(KO.IEC) mice were healthy and did not develop spontaneous disease. However, these mice were hypersensitive to mucosal insults and displayed defective repair.

GASTROENTEROLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Bifidobacterium bifidum Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner

Rana Al-Sadi et al.

Summary: The probiotic bacteria BB1 causes a strain-specific enhancement of the intestinal TJ barrier through a novel mechanism involving BB1 attachment to the enterocyte TLR-2 receptor complex and activation of p38 kinase pathway. This enhancement is sustained, and BB1 strain designated as BB1 causes a maximal enhancement in TJ barrier function. The mechanism of BB1 enhancement of intestinal TJ barrier is mediated by the p38 kinase pathway, not the NF-kappa B signaling pathway.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

Bifidobacterium dentium-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation

Melinda A. Engevik et al.

Summary: This study demonstrates that secreted factors from Bifidobacterium dentium can reduce ER stress genes, promote MUC2 secretion, suppress inflammation, and positively modulate the UPR, showing potential benefits for inflammatory bowel diseases.

GUT MICROBES (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease

Lisa Mayr et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Commensal epitopes drive differentiation of colonic Tregs

Michal P. Kuczma et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Immunomodulation and Generation of Tolerogenic Dendritic Cells by Probiotic Bacteria in Patients with Inflammatory Bowel Disease

Shaghayegh Baradaran Ghavami et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Integrated microbiota and metabolite profiles link Crohn's disease to sulfur metabolism

Amira Metwaly et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Fisheries

Bifidobacterium longum and VSL#3® amelioration of TNBS-induced colitis associated with reduced HMGB1 and epithelial barrier impairment

Xiaohong Chen et al.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide

Matthew T. Henke et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

添加到收藏夹

Article Immunology

Strain-Specific Anti-inflammatory Properties of Two Akkermansia muciniphila Strains on Chronic Colitis in Mice

Rui Zhai et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2019)

添加到收藏夹

Article Chemistry, Applied

Bifidobacterium bifidum presents on the cell surface a complex mixture of glucans and galactans with different immunological properties

Immacolata Speciale et al.

CARBOHYDRATE POLYMERS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Remission in Crohn's disease is accompanied by alterations in the gut microbiota and mucins production

Daniela Oliveira Magro et al.

SCIENTIFIC REPORTS (2019)

添加到收藏夹

Editorial Material Gastroenterology & Hepatology

Evolving Considerations for Thiopurine Therapy for Inflammatory Bowel Diseases-A Clinical Practice Update: Commentary

Stephen B. Hanauer et al.

GASTROENTEROLOGY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Protective effects of a novel probiotic strain, Lactococcus lactis ML2018, in colitis: in vivo and in vitro evidence

Meiling Liu et al.

FOOD & FUNCTION (2019)

添加到收藏夹

Article Cell Biology

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

Arnau Vich Vila et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

添加到收藏夹

Article Engineering, Environmental

Effects of Dietary Selenium Supplementation on Intestinal Barrier and Immune Responses Associated with Its Modulation of Gut Microbiota

Qixiao Zhai et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS (2018)

添加到收藏夹

Article Immunology

Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T cells

Ravi Verma et al.

SCIENCE IMMUNOLOGY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Bifidobacterium adolescentis Exerts Strain-Specific Effects on Constipation Induced by Loperamide in BALB/c Mice

Linlin Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

添加到收藏夹

Article Biochemical Research Methods

Chemically induced mouse models of acute and chronic intestinal inflammation

Stefan Wirtz et al.

NATURE PROTOCOLS (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Exosomes Derived from Dendritic Cells Treated with Schistosoma japonicum Soluble Egg Antigen Attenuate DSS-Induced Colitis

Lifu Wang et al.

FRONTIERS IN PHARMACOLOGY (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Effects of subchronic oral toxic metal exposure on the intestinal microbiota of mice

Qixiao Zhai et al.

SCIENCE BULLETIN (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Butyrate-producing bacteria supplemented in vitro to Crohn's disease patient microbiota increased butyrate production and enhanced intestinal epithelial barrier integrity

Annelies Geirnaert et al.

SCIENTIFIC REPORTS (2017)

添加到收藏夹

Article Microbiology

Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn's Disease

G. Hoarau et al.

MBIO (2016)

添加到收藏夹

Article Gastroenterology & Hepatology

The Probiotic VSL#3 Has Anti-inflammatory Effects and Could Reduce Endoscopic Recurrence After Surgery for Crohn's Disease

Richard N. Fedorak et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2015)

添加到收藏夹

Article Gastroenterology & Hepatology

Moxibustion combined with acupuncture increases tight junction protein expression in Crohn's disease patients

Hai-Xia Shang et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Lactosucrose attenuates intestinal inflammation by promoting Th2 cytokine production and enhancing CD86 expression in colitic rats

Yan Zhou et al.

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Bifidobacterium longum CCM 7952 Promotes Epithelial Barrier Function and Prevents Acute DSS-Induced Colitis in Strictly Strain-Specific Manner

Dagmar Srutkova et al.

PLOS ONE (2015)

添加到收藏夹

Review Gastroenterology & Hepatology

Mechanisms of initiation and progression of intestinal fibrosis in IBD

Giovanni Latella et al.

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2015)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Bifidobacterium bifidum PRL2010 Modulates the Host Innate Immune Response

Francesca Turroni et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2014)

添加到收藏夹

Article Microbiology

The σE Pathway Is Involved in Biofilm Formation by Crohn's Disease-Associated Adherent-Invasive Escherichia coli

Benoit Chassaing et al.

JOURNAL OF BACTERIOLOGY (2013)

添加到收藏夹

Article Pharmacology & Pharmacy

Protective effects of Ulmus macrocarpa on experimental colitis mice models

Jae-Woo Park et al.

ORIENTAL PHARMACY AND EXPERIMENTAL MEDICINE (2011)

添加到收藏夹

Article Immunology

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease

Masayuki Saruta et al.

CLINICAL IMMUNOLOGY (2007)

添加到收藏夹

Article Gastroenterology & Hepatology

High dose probiotic and prebiotic cotherapy for remission induction of active Crohn's disease

Shunji Fujimori et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2007)

添加到收藏夹

Article Cell Biology

Modulation of apoptosis in intestinal lymphocytes by a probiotic bacteria in Crohn's disease

Monica Carol et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2006)

添加到收藏夹

Article Gastroenterology & Hepatology

Inhibitory effect of probiotic Escherichia coli strain Nissle 1917 on adhesion to and invasion of intestinal epithelial cells by adherent-invasive E-coli strains isolated from patients with Crohn's disease

J Boudeau et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2003)

添加到收藏夹

Article Gastroenterology & Hepatology

Saccharomyces boulardii in maintenance treatment of Crohn's disease

M Guslandi et al.

DIGESTIVE DISEASES AND SCIENCES (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.