Efficiency and Safety of Baofei Granules in Chronic Obstructive Pulmonary Disease (Lung and Spleen Qi Deficiency Syndrome): A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial

Article Integrative & Complementary Medicine

Associations of Chinese Herbal Medicine Use with the Risks of Acute Exacerbation and Mortality in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Cohort Study

Jui-Hung Hung et al.

Summary: This study aimed to assess the correlation between biomedical treatments with or without Chinese herbal medicine (CHM) and the exacerbation and mortality rate in patients with chronic obstructive pulmonary disease (COPD). The results showed that COPD patients who received CHM as an adjunct demonstrated a lower risk of mortality and acute exacerbation compared to those who did not receive CHM. In addition, the CHM users had a reduced cumulative incidence of mortality.

JOURNAL OF INTEGRATIVE AND COMPLEMENTARY MEDICINE (2022)

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Article Respiratory System

Osteoporosis and fracture risk associated with inhaled corticosteroid use among Swedish COPD patients: the ARCTIC study

Christer Janson et al.

Summary: Analysis of long-term medical record data on COPD patients and matched controls revealed that patients with COPD have a higher risk of bone fractures and osteoporosis, with high-dose ICS use further increasing this risk.

EUROPEAN RESPIRATORY JOURNAL (2021)

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Review Integrative & Complementary Medicine

The Effectiveness of Traditional Chinese Medicine (TCM) as an Adjunct Treatment on Stable COPD Patients: A Systematic Review and Meta-Analysis

K. H. Chan et al.

Summary: A systematic review of 100 randomized controlled trials revealed that combining Chinese herbal medicine with conventional treatment improves lung function, reduces exacerbation rates, and enhances COPD assessment test and TCM syndrome score in stable COPD patients. While no serious adverse events were reported, further studies with larger sample sizes are needed to confirm these findings.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2021)

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Article Medicine, General & Internal

Chinese Medicine for Chronic Obstructive Pulmonary Disease: A Pilot Study on Patient Preferences

Shaonan Liu et al.

Summary: The study found that COPD patients prefer a combination of traditional Chinese and Western medicine, with Chinese patent medicine and decoction therapy being the preferred complementary medicines. The most desired clinical outcomes for patients were improvements in dyspnea, cough symptoms, and lung function. Key factors influencing treatment selection included speed of symptom relief, cost, and side effects.

PATIENT PREFERENCE AND ADHERENCE (2021)

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Review Pharmacology & Pharmacy

Inhaled Corticosteroids and the Pneumonia Risk in Patients With Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials

Hong Chen et al.

Summary: Inhaled corticosteroids (ICS) treatment significantly increased the risk of pneumonia in patients with chronic obstructive pulmonary disease (COPD), with a dose-response relationship between ICS treatment and pneumonia risk. The risk of pneumonia was related to the severity of COPD.

FRONTIERS IN PHARMACOLOGY (2021)

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Article Integrative & Complementary Medicine