相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability
Keelan Z. Guiley et al.
CANCER DISCOVERY (2023)
First-in-human study of PC14586, a small molecule structural corrector of Y220C mutant p53, in patients with advanced solid tumors harboring a TP53 Y220C mutation.
Ecaterina Elena Dumbrava et al.
JOURNAL OF CLINICAL ONCOLOGY (2022)
Cancer drugs are closing in on some of the deadliest mutations
Heidi Ledford
NATURE (2022)
Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas
Lawrence A. Donehower et al.
CELL REPORTS (2019)
Li-Fraumeni syndrome: cancer risk assessment and clinical management
Kate A. McBride et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2014)
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
Jonathan M. Ostrem et al.
NATURE (2013)
Targeted rescue of a destabilized mutant of p53 by an in silico screened drug
Frank M. Boeckler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers
Lawrence R. Dearth et al.
CARCINOGENESIS (2007)
分享论文
