相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling
Miriam Doepner et al.
SCIENCE ADVANCES (2022)
Map3k1 Loss Cooperates with BrafV600E to Drive Melanomagenesis
Lucas D. Trucco et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2021)
BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response inTP53wild-type breast cancer
Ashkan Shahbandi et al.
CELL DEATH AND DIFFERENTIATION (2020)
MARCH5 mediates NOXA-dependent MCL1 degradation driven by kinase inhibitors and integrated stress response activation
Seiji Arai et al.
ELIFE (2020)
Role of immune cells in the removal of deleterious senescent cells
Abhijit Kale et al.
IMMUNITY & AGEING (2020)
Simultaneously Inhibiting BCL2 and MCL1 Is a Therapeutic Option for Patients with Advanced Melanoma
Nabanita Mukherjee et al.
CANCERS (2020)
Cellular senescence impairs the reversibility of pulmonary arterial hypertension
Diederik E. van der Feen et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
A Senescence-Centric View of Aging Implications for Longevity and Disease
M. Borghesan et al.
TRENDS IN CELL BIOLOGY (2020)
MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells
Nabanita Mukherjee et al.
CELL DEATH & DISEASE (2020)
Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
Peter J. Thompson et al.
CELL METABOLISM (2019)
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival
Erinna F. Lee et al.
CELL DEATH & DISEASE (2019)
Regulation of Survival Networks in Senescent Cells: From Mechanisms to Interventions
Abel Soto-Gamez et al.
JOURNAL OF MOLECULAR BIOLOGY (2019)
Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction
Stella Victorelli et al.
EMBO JOURNAL (2019)
Ultraviolet radiation-induced DNA damage is prognostic for outcome in melanoma
Lucas D. Trucco et al.
NATURE MEDICINE (2019)
Hallmarks of Cellular Senescence
Alejandra Hernandez-Segura et al.
TRENDS IN CELL BIOLOGY (2018)
Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade
Christopher A. Natale et al.
ELIFE (2018)
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
Tyler J. Bussian et al.
NATURE (2018)
Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
Marco Demaria et al.
CANCER DISCOVERY (2017)
Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells
Nabanita Mukherjee et al.
ONCOTARGET (2017)
A meta-analysis of nevus-associated melanoma: Prevalence and practical implications
Riccardo Pampena et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2017)
Unmasking Transcriptional Heterogeneity in Senescent Cells
Alejandra Hernandez-Segura et al.
CURRENT BIOLOGY (2017)
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
Yi Zhu et al.
AGING-US (2017)
Polysome Fractionation to Analyze mRNA Distribution Profiles
Amaresh C. Panda et al.
BIO-PROTOCOL (2017)
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
Jianhui Chang et al.
NATURE MEDICINE (2016)
Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
Yi Zhu et al.
AGING CELL (2016)
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
Andras Kotschy et al.
NATURE (2016)
Senescent intimal foam cells are deleterious at all stages of atherosclerosis
Bennett G. Childs et al.
SCIENCE (2016)
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation
Grace R. Anderson et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
Reut Yosef et al.
NATURE COMMUNICATIONS (2016)
Comparative analysis of colorimetric staining in skin using open-source software
Paul C. Billings et al.
EXPERIMENTAL DERMATOLOGY (2015)
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer
Anthony C. Faber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1
Naotaka Sekiyama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
J. D. Leverson et al.
CELL DEATH & DISEASE (2015)
CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma
Andrew S. McNeal et al.
CANCER DISCOVERY (2015)
The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells
Bin Wang et al.
MOLECULAR CANCER (2014)
Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53
Amaya Viros et al.
NATURE (2014)
Elucidating Distinct Roles for NF1 in Melanomagenesis
Ophelia Maertens et al.
CANCER DISCOVERY (2013)
Congenital melanocytic nevi: Where are we now? Part II. Treatment options and approach to treatment
Omar A. Ibrahimi et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2012)
Temsirolimus Inhibits Malignant Pleural Mesothelioma Growth In Vitro and In Vivo Synergism with Chemotherapy
Mir Alireza Hoda et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor
Bao Hoang et al.
BLOOD (2010)
Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice
Nathalie Dhomen et al.
CANCER CELL (2009)
Synergistic antiproliferative effect of mTOR inhibitors in combination with 5-fluorouracil in scirrhous gastric cancer
Taro Matsuzaki et al.
CANCER SCIENCE (2009)
BrafV600E cooperates with Pten loss to induce metastatic melanoma
David Dankort et al.
NATURE GENETICS (2009)
mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia
David T. Teachey et al.
BLOOD (2008)
ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
Christin Tse et al.
CANCER RESEARCH (2008)
mTORC1 promotes survival through translational control of Mcl-1
John R. Mills et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations
Juergen Bauer et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)
Oncogene-induced cell senescence - Halting on the road to cancer
W. J. Mooi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V. C. Gray-Schopfer et al.
BRITISH JOURNAL OF CANCER (2006)
Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts
K Mercer et al.
CANCER RESEARCH (2005)
BRAFE600-associated senescence-like cell cycle arrest of human naevi
C Michaloglou et al.
NATURE (2005)
BRAF mutations are common somatic events in melanocytic nevi
R Kumar et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
High frequency of BRAF mutations in nevi
PM Pollock et al.
NATURE GENETICS (2003)
分享论文
