4.8 Article

Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition

Chunxia Zhang et al.

Summary: Transcriptional regulation is important in early mouse embryo development. Using a new technique, the mRNA translation landscape of mouse preimplantation embryos was revealed, showing the critical role of active translation of maternal mRNAs in maternal-to-zygotic transition. The study also identified two maternal factors required for chromatin reprogramming and zygotic genome activation.

SCIENCE ADVANCES (2022)

Article Biochemistry & Molecular Biology

LncRNA NEAT1 promotes glioma cancer progression via regulation of miR-98-5p/BZW1

Yabin Li et al.

Summary: NEAT1 plays an oncogenic role in glioma progression by promoting cell proliferation and interacting with miR-98-5p and BZW1. Inhibition of NEAT1 through the miR-98-5p/BZW1 pathway suppresses glioma cell proliferation in vivo. Targeting NEAT1/miR-98-5p/BZW1 may provide a novel therapeutic approach for glioma patients.

BIOSCIENCE REPORTS (2021)

Article Cell Biology

BZW1 promotes cell proliferation in prostate cancer by regulating TGF-β1/Smad pathway

Zhenfeng Shi et al.

Summary: The study suggests that high expression of BZW1 in prostate cancer is associated with tumor progression and poor prognosis, promoting cell proliferation by regulating the TGF-beta 1/Smad pathway.

CELL CYCLE (2021)

Article Developmental Biology

Regulation of the mammalian maternal-to-embryonic transition by eukaryotic translation initiation factor 4E

Yan Li et al.

Summary: The translation initiation factor eIF4E plays a crucial role in cap-dependent translation and the transition from maternal to embryonic control of mouse embryo development. Inhibiting eIF4E activity leads to developmental arrest at the two-cell stage, highlighting the importance of eIF4E in early embryonic transitions. This study also shows that mTOR activity and the negative regulator 4E-BP1 are involved in regulating eIF4E activity during embryonic development.

DEVELOPMENT (2021)

Article Cell Biology

Nuclear-localized eukaryotic translation initiation factor 1A is involved in mouse preimplantation embryo development

Yue Liu et al.

Summary: This study revealed the important role of eIF1A in early mouse preimplantation embryo development. Knockdown of eIF1A affected blastocyst formation rate, down-regulated CDX2 protein expression level, and decreased Hsp70.1 mRNA expression level in 2-cell embryos.

JOURNAL OF MOLECULAR HISTOLOGY (2021)

Article Biology

The molecular basis of coupling between poly(A)-tail length and translational efficiency

Kehui Xiang et al.

Summary: The study found that mRNA poly(A)-tail length strongly influences translational efficiency (TE) in animal oocytes and early embryos, but this coupling disappears later in development. Overexpressing cytoplasmic poly(A)-binding protein weakened the coupling between tail length and TE, while postembryonic mammalian cell lines had properties preventing strong coupling.
Article Biochemistry & Molecular Biology

The CRL4-DCAF13 ubiquitin E3 ligase supports oocyte meiotic resumption by targeting PTEN degradation

Jue Zhang et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2020)

Article Biochemistry & Molecular Biology

PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal-to-zygotic transition

Long-Wen Zhao et al.

EMBO REPORTS (2020)

Article Biochemistry & Molecular Biology

eIF2α interactions with mRNA control accurate start codon selection by the translation preinitiation complex

Anil Thakur et al.

NUCLEIC ACIDS RESEARCH (2020)

Article Multidisciplinary Sciences

Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans

Qian-Qian Sha et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

Developmental clock and mechanism of de novo polarization of the mouse embryo

Meng Zhu et al.

SCIENCE (2020)

Review Cell Biology

Mammalian zygotic genome activation

Petr Svoboda

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2018)

Review Cell Biology

Non-AUG translation: a new start for protein synthesis in eukaryotes

Michael G. Kearse et al.

GENES & DEVELOPMENT (2017)

Review Biochemistry & Molecular Biology

The first cell-fate decision of mouse preimplantation embryo development: integrating cell position and polarity

Aleksandar I. Mihajlovic et al.

OPEN BIOLOGY (2017)

Review Cell Biology

Zygotic Genome Activation in Vertebrates

David Jukam et al.

DEVELOPMENTAL CELL (2017)

Article Biochemistry & Molecular Biology

Chk2 Regulates Cell Cycle Progression during Mouse Oocyte Maturation and Early Embryo Development

Xiao-Xin Dai et al.

MOLECULES AND CELLS (2014)

Article Biochemical Research Methods

Full-length RNA-seq from single cells using Smart-seq2

Simone Picelli et al.

NATURE PROTOCOLS (2014)

Article Cell & Tissue Engineering

Connexin31.1 (Gjb5) Deficiency Blocks Trophoblast Stem Cell Differentiation and Delays Placental Development

Mark Kibschull et al.

STEM CELLS AND DEVELOPMENT (2014)

Article Biochemistry & Molecular Biology

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

Yoshikazu Hirate et al.

CURRENT BIOLOGY (2013)

Article Cell Biology

Cadherin-dependent filopodia control preimplantation embryo compaction

Juan Carlos Fierro-Gonzalez et al.

NATURE CELL BIOLOGY (2013)

Review Biochemistry & Molecular Biology

A mechanistic overview of translation initiation in eukaryotes

Colin Echeverria Aitken et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5

Gary Loughran et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Multidisciplinary Sciences

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

Sooncheol Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Cell Biology

The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes

Thomas E. Dever et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Functional Elements in Initiation Factors 1, 1A, and 2β Discriminate against Poor AUG Context and Non-AUG Start Codons

Pilar Martin-Marcos et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Mechanisms of translational regulation by a human eIF5-mimic protein

Chingakham Ranjit Singh et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Developmental Biology

Klf5 regulates lineage formation in the pre-implantation mouse embryo

Suh-Chin J. Lin et al.

DEVELOPMENT (2010)

Review Biochemistry & Molecular Biology

Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

A. Satyanarayana et al.

ONCOGENE (2009)

Article Biochemistry & Molecular Biology

Sister chromatid cohesion and genome stability in vertebrate cells

C Morrison et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2003)