Epidemiology of Infectious Bursal Disease Virus in Poland during 2016-2022

Infectious bursal disease virus is an immunosuppressive ubiquitous pathogen that causes serious economic losses in poultry production. The virus is prone to genetic changes through mutations and reassortment, which drive the emergence of new variants and lead to a change in the epidemiological situation in a field. Such a situation is currently being reported due to a large wave of IBDV A3B1 reassortant infections in northwestern Europe. On the other hand, in Poland, which is the largest producer of chicken meat in the EU, the IBDVs of genotypes A3B2 and A3B4 were circulating just before the emergence of A3B1 reassortants. The purpose of the presented study was to update the IBDV epidemiological situation. The performed molecular survey based on the sequence of both genome segments showed the presence of very virulent strains (A3B2) and reassortants of genotypes A3B4 and A3B1; moreover, two of these genotypes are newly introduced IBDV lineages. In addition, a number of amino acid substitutions were demonstrated, including within antigenic epitopes and virulence determinants. In conclusion, the results obtained indicated a dynamic epidemiological situation in Poland, which highlights the need for further monitoring studies in the region and verification of protection conferred by the vaccines used against infection with detected IBDV.

Automated summary

Infectious bursal disease virus (IBDV) is a widespread immunosuppressive pathogen that causes significant losses in poultry production. It undergoes genetic changes through mutations and reassortment, leading to the emergence of new variants and changing the epidemiological situation. A recent study in northwestern Europe reported a large wave of IBDV A3B1 reassortant infections. In Poland, the largest producer of chicken meat in the EU, IBDV genotypes A3B2 and A3B4 were circulating before the emergence of A3B1 reassortants.