☆ 4.6 Article

Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma

WORLD JOURNAL OF SURGICAL ONCOLOGY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Gastroenterology & Hepatology

Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment

Zhibo Xie et al.

Summary: This study revealed that PDAC-derived exosomes play a crucial role in modulating the liver microenvironment and promoting liver metastasis. The CD44v6/C1QBP complex delivered by exosomes to hepatic satellite cells leads to activation of insulin-like growth factor 1 signaling molecules and liver fibrosis. High expression of exosomal CD44v6 and C1QBP in PDAC patients is associated with liver metastasis.

GUT (2022)

添加到收藏夹

Article Oncology

Exosome-mediated remodeling of the tumor microenvironment: From local to distant intercellular communication

Yujuan Huang et al.

Summary: This review summarizes the latest progress in the exploration of exosome-mediated cell-cell communication implicated in tumor microenvironment (TME) remodeling and underlying mechanisms. It focuses on the role of cell-cell interactions mediated by tumor cell-derived exosomes in promoting invasion and metastasis, and their potential as a therapeutic intervention target against distant metastasis. The clinical translational significance of tumor-derived exosomes for early diagnosis, efficacy, and progression evaluations is also discussed.

CANCER LETTERS (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Establishment of a Genomic-Clinicopathologic Nomogram for Predicting Early Recurrence of Hepatocellular Carcinoma After R0 Resection

Bin Yu et al.

Summary: This study identified nine dysregulated and prognostic genes related to early recurrence (ER) in hepatocellular carcinoma (HCC) patients after R0 resection, and successfully constructed a prognostic index model based on these genes. The genomic-clinicopathologic nomogram integrating this model showed significantly higher predictive accuracy and clinical application value in predicting ER compared to TNM stage model.

JOURNAL OF GASTROINTESTINAL SURGERY (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Extracellular vesicles in hepatology: Physiological role,involvement in pathogenesis, and therapeutic opportunities

Maria Azparren-Angulo et al.

Summary: The number of publications on Extracellular Vesicles (EVs) released by liver cells has exponentially increased since the first descriptions in 2008, indicating the growing interest in the importance of cell-to-cell communication and the potential of these vesicles in diagnostics and therapeutics. This systematic review summarizes the works from the past decade and discusses the best opportunities for utilizing EVs in liver disease therapeutics.

PHARMACOLOGY & THERAPEUTICS (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Article Oncology

Alterations of the Platelet Proteome in Lung Cancer: Accelerated F13A1 and ER Processing as New Actors in Hypercoagulability

Huriye Ercan et al.

Summary: The study revealed that the biochemical changes in platelets of cancer patients, particularly lung cancer patients, may be associated with an increased risk of thrombosis. Specific alterations in platelet proteome were found in lung cancer patients, including elevated levels of certain proteins which may directly promote thrombosis.

CANCERS (2021)

添加到收藏夹

Article Immunology

A Novel Immune-Related Seventeen-Gene Signature for Predicting Early Stage Lung Squamous Cell Carcinoma Prognosis

Tao Fan et al.

Summary: An immune-related gene signature was developed to predict the outcome of early stage LUSC, identifying 17 immune-related genes as potential prognostic markers. The signature showed promise in predicting overall survival and was validated in multiple cohorts, indicating its potential for tailored immunotherapeutic options.

FRONTIERS IN IMMUNOLOGY (2021)

添加到收藏夹

Article Oncology

Hepatobiliary Cancers, Version 2.2021

Al B. Benson III et al.

Summary: The NCCN Guidelines for Hepatobiliary Cancers provide recommendations for screening, diagnosis, staging, treatment, and management of HCC, gallbladder cancer, and cancer of the bile ducts. A multidisciplinary evaluation is crucial for determining optimal treatment strategies, with significant advancements in systemic treatment of HCC beyond traditional options like sorafenib.

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Complement C1q mediates the expansion of periportal hepatic progenitor cells in senescence-associated inflammatory liver

Tung-Ching Ho et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Complement factor H-deficient mice develop spontaneous hepatic tumors

Jennifer Laskowski et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view

Sara Thietart et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Discovery of small extracellular vesicle proteins from human serum for liver cirrhosis and liver cancer

Asad Uzzaman et al.

BIOCHIMIE (2020)

添加到收藏夹

Article Medicine, General & Internal

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Theo Vos et al.

LANCET (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Knockout of PRDX6 induces mitochondrial dysfunction and cell cycle arrest at G2/M in HepG2 hepatocarcinoma cells

Maria Jose Lopez-Grueso et al.

REDOX BIOLOGY (2020)

添加到收藏夹

Article Cell Biology

Tumour extracellular vesicle-derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement-dependent cytotoxicity of tumour cells

Xiaowen Mao et al.

JOURNAL OF EXTRACELLULAR VESICLES (2020)

添加到收藏夹

Review Oncology

Isolation and characterization of exosomes for cancer research

Le Zhu et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)

添加到收藏夹

Review Oncology

Exosomes as a Multicomponent Biomarker Platform in Cancer

Valerie S. LeBleu et al.

TRENDS IN CANCER (2020)

添加到收藏夹

Article Plant Sciences

Increased biomass accumulation in maize grown in mixed nitrogen supply is mediated by auxin synthesis

Peng Wang et al.

JOURNAL OF EXPERIMENTAL BOTANY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

Rongkun Li et al.

MOLECULAR CANCER (2019)

添加到收藏夹

Review Cell Biology

Exosome-Mediated Metastasis: Communication from a Distance

Inbal Wortzel et al.

DEVELOPMENTAL CELL (2019)

添加到收藏夹

Article Oncology

Potential Markers from Serum-Purified Exosomes for Detecting Oral Squamous Cell Carcinoma Metastasis

Cuiping Li et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2019)

添加到收藏夹

Review Cell Biology

Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease

Marcelo A. Mori et al.

CELL METABOLISM (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

Qihan Fu et al.

ONCOGENE (2018)

添加到收藏夹

Article Biochemical Research Methods

Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer

Julien Peltier et al.

CLINICAL PROTEOMICS (2018)

添加到收藏夹

Article Cell Biology

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Thery et al.

JOURNAL OF EXTRACELLULAR VESICLES (2018)

添加到收藏夹

Article Multidisciplinary Sciences

C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation

Roberta Bulla et al.

NATURE COMMUNICATIONS (2016)

添加到收藏夹

Article Oncology

Hepatitis B virus X protein up-regulates C4b-binding protein β through activating transcription factor Sp1 in protection of hepatoma cells from complement attack

Guoxing Feng et al.

ONCOTARGET (2016)

添加到收藏夹

Article Oncology

Downregulation of matrix metalloproteinases contributes to the inhibition of cell migration and invasion in HepG2 cells by sodium valproate

Xia Zhao et al.

ONCOLOGY LETTERS (2015)

添加到收藏夹

Article Oncology

Elevated Plasma Fibrinogen Levels Are Associated with a Poor Prognosis in Patients with Hepatocellular Carcinoma

Akiyoshi Kinoshita et al.

ONCOLOGY (2013)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.