Identification and characterization of an envelope protein 168L in Cherax quadricarinatus iridovirus (CQIV)

Article Zoology

Interaction between 038R and 125R of Cherax quadricarinatus iridovirus (CQIV) and their effects on virus replication

Qin Zheng et al.

Summary: This study identified the interaction between core proteins in Cherax quadricarinatus iridovirus (CQIV) and demonstrated their essential role in viral replication.

JOURNAL OF INVERTEBRATE PATHOLOGY (2022)

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Article Biochemistry & Molecular Biology

Replication and transcription machinery for ranaviruses: components, correlation, and functional architecture

Fei Ke et al.

Summary: Using a series of precise methods, this study identified the replication and transcription machinery of two ranaviruses, Andrias davidianus ranavirus (ADRV) and Rana grylio virus (RGV), and found that it consists of a complex apparatus containing at least 30 viral and 6 host proteins. The core replisome is composed of viral proteins such as ADRV-47L/RGV-63R (DNA polymerase, vDPOL), ADRV-23L/RGV-91R (proliferating cell nuclear antigen, vPCNA), ADRV-85L/RGV-27R (single-stranded DNA binding protein, vSSB), and ADRV-88L/RGV-24R (vhelicase/primase). Additionally, the core of the transcription complex includes the host RNAPII subunits Rpb3, Rpb6, and Rpb11, which is a first report in NCLDVs. The results provide insight into the architecture of ranavirus replication and transcription, with vDPOL playing a central role and various components working together.

CELL AND BIOSCIENCE (2022)

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Article Virology

Proteomic analysis of the Decapod iridescent virus 1

Yanlin You et al.

Summary: This study analyzed the structural proteins of Decapod iridescent virus 1 (DIV1) using mass spectrometry. The researchers purified DIV1 virions from infected Cherax quadricarinatus and identified 30 virus-encoded proteins. The findings provide a foundation for further investigation into viral infection and replication.

VIRUS RESEARCH (2022)

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Article Virology

Complete genome reconstruction and genetic analysis of Taura syndrome virus of shrimp from archival Davidson's-fixed paraffin embedded tissue

Roberto Cruz-Flores et al.

Summary: DFPE shrimp tissues are valuable biological resources for pathogen discovery and evolutionary studies. This study successfully reconstructed the complete genome of shrimp RNA virus TSV from archived DFPE tissues using NGS, demonstrating the utility of archived samples for viral identification and evolutionary research.

VIROLOGY (2021)

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Article Fisheries

Establishment of infection mode and Penaeus monodon hemocytes transcriptomics analysis under decapod iridescent virus 1 (DIV1) challenge

Zihao He et al.

Summary: This study established a stable and effective infection model for DIV1 in Penaeus monodon, and used RNA-Seq platform and bioinformatics analysis to investigate the immune response to DIV1 infection, revealing significant changes in immune-related pathways. The study provides valuable genetic resources and research methods for developing molecular markers for DIV1-resistant P. monodon families. Ultimately, the goal is to prevent disease outbreaks in shrimp farming.

AQUACULTURE (2021)

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Article Fisheries