4.7 Review

Biosensors for healthcare: current and future perspectives

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TRENDS IN BIOTECHNOLOGY
卷 41, 期 3, 页码 374-395

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CELL PRESS
DOI: 10.1016/j.tibtech.2022.12.005

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In this review, we discuss recent developments in biosensors for healthcare, which are used in various fields like medicine, food, and environment. These biosensors include in vitro diagnosis biosensors, continuous monitoring biosensors, and wearable biosensors. In vitro diagnosis biosensors have expanded significantly lately, with the introduction of CRISPR/Cas methodologies and improvements to existing integrated biosensor devices. We also discuss the emerging groups of continuous monitoring and wearable biosensors, as well as the outlook for commercialization and future of biosensors.
Biosensors are utilized in several different fields, including medicine, food, and the environment; in this review, we examine recent developments in biosensors for healthcare. These involve three distinct types of biosensor: biosensors for in vitro diagnosis with blood, saliva, or urine samples; continuous monitoring biosensors (CMBs); and wearable biosensors. Biosensors for in vitro diagnosis have seen a significant expansion recently, with newly reported clustered regu-larly interspaced short palindromic repeats (CRISPR)/Cas methodologies and improvements to many established integrated biosensor devices, including lat-eral flow assays (LFAs) and microfluidic/electrochemical paper-based analytical devices (mu PADs/ePADs). We conclude with a discussion of two novel groups of biosensors that have drawn great attention recently, continuous monitoring and wearable biosensors, as well as with perspectives on the commercialization and future of biosensors.

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