Microfluidic trends in drug screening and drug delivery

The low probability of a drug candidate's clinical success, the time consumed and the high cost of bringing a drug from concept to market emphasizes the need for new approaches to drug discovery. Recent innovations in microfluidic technologies, including organ-on-a-chip, droplet microfluidics and high-throughput screening are revealing the potential of these platforms to address some of these challenges, due to the small volume of samples consumed, short processing time, and improved process control. Here, we review selected recent progress in the development and application of microfluidic technologies in drug screening and drug delivery, highlighting the trends and associated challenges.& COPY; 2022 Published by Elsevier B.V.

Automated summary

The low success rate, time consumption, and high cost of bringing a drug from concept to market necessitate new approaches to drug discovery. Recent innovations in microfluidic technologies, such as organ-on-a-chip, droplet microfluidics, and high-throughput screening, have shown potential in addressing these challenges through reduced sample volume, faster processing time, and improved process control. This review highlights the recent progress in the development and application of microfluidic technologies in drug screening and drug delivery, outlining the trends and associated challenges.