4.7 Review

Recent advances in microfluidic sensors for nutrients detection in water

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Portable smartphone-based colorimetric system for simultaneous on-site microfluidic paper-based determination and mapping of phosphate, nitrite and silicate in coastal waters

Ahmad Manbohi et al.

Summary: This paper describes a method combining microfluidic paper-based sensors and an Android-based smartphone application for on-site quantification of phosphate, silicate, and nitrite in coastal seawater. The developed application can capture, process, and quantify the colorimetric outputs of the sensors, and store or share the GPS-tagged data. The method showed wide linear ranges and low limits of detection under optimized parameters.

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Lab-on-Chip for In Situ Analysis of Nutrients in the Deep Sea

Alexander D. Beaton et al.

Summary: A new family of miniaturized lab-on-chip colorimetric analyzers has been developed for in situ nitrate and phosphate measurements in the ocean, suitable for depths up to >4800 m. The analyzers show comparable performance to laboratory-based analyses and offer a new low-cost, high-performance tool for measuring chemistry in hyperbaric environments.

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Article Biophysics

A microfluidic biosensor for rapid simultaneous detection of waterborne pathogens

Sura A. Muhsin et al.

Summary: A microfluidic based biosensor was used for rapid and simultaneous detection of Salmonella, Legionella, and Escherichia coli O157:H7 in tap water and wastewater. The biosensor concentrated and detected bacteria at both low and high concentrations. The results showed that the biosensors could detect the three bacterial pathogens simultaneously with a detection limit of 3 bacterial cells/mL in 30-40 minutes.

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Calibration-free mid-infrared exhaled breath sensor based on BF-QEPAS for real-time ammonia measurements at ppb level

Biao Li et al.

Summary: In this study, a calibration-free mid-infrared exhaled breath sensor is demonstrated for real-time measurement of ammonia at ppb-level, which can be used for non-invasive diagnosis of liver and kidney diseases.

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Review Virology

Microfluidic devices for detection ofRNAviruses

Arefeh Basiri et al.

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Utility of low-cost, miniaturized peristaltic and Venturi pumps in droplet microfluidics

Joshua J. Davis et al.

Summary: This study explores the potential use of an open-source peristaltic pump and a low-cost commercial Venturi pump as alternatives to precision syringe pumps for droplet microfluidics. Both devices provided stable flow and high reproducibility in signal intensity, making them suitable for common droplet microfluidic applications.

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A New Paper-Based Microfluidic Device for Improved Detection of Nitrate in Water

Amer Charbaji et al.

Summary: The paper presents a simple and cost-effective paper-based microfluidic device for detecting nitrate in water. By incorporating recent advancements in paper-based technology suitable for nitrate detection, the device achieved significant improvement in nitrate detection compared to previous methods.

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Efficient Microfluidic-Based Air Sampling/Monitoring Platform for Detection of Aerosol SARS-CoV-2 On-site

Huiwen Xiong et al.

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Sensing of inorganic ions in microfluidic devices

Renjie Wang et al.

Summary: This review focuses on the widespread adoption of microfluidics for chemical analysis in the past two decades, with a particular emphasis on the sensing of inorganic ions in microfluidic devices. Various ion sensing schemes and microfluidic platforms are covered, providing insights into the development and potential advancements of microfluidic ion sensors.

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Wireless Microfluidic Sensor for Metal Ion Detection in Water

Yu Liang et al.

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Huanhuan Shi et al.

Summary: The study focuses on recent methods of ion measurement using microfluidic devices, highlighting potential applications in sample treatment, ion chelating mechanisms, and ion detection strategies, with promising developments in water quality monitoring, healthcare diagnostic testing, and portable device technologies.

MICROCHEMICAL JOURNAL (2021)

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A portable analytical system for rapid on-site determination of total nitrogen in water

Chen Zhao et al.

Summary: This paper presents a portable TN analytical system for on-site measurement of TN, achieving fast oxidation and colorimetric determination within 36 minutes. By optimizing reaction conditions and reagent volumes, the system is able to digest and measure TN in a quick, portable, and low-cost manner.

WATER RESEARCH (2021)

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An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

Benjamin J. Murphy et al.

Summary: A novel method of conserving heat energy in microfluidic systems has been proposed, which reduces heat transfer by surrounding the heated optical cell with air pockets. The insulated design significantly reduces power consumption and performs well in nitrate concentration measurements.

MICROMACHINES (2021)

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Interfacing droplet microfluidics with antibody barcodes for multiplexed single-cell protein secretion profiling

Tahereh Khajvand et al.

Summary: This study introduces an integrated droplet microfluidic device for multiplexed single-cell secretion analysis, which can effectively capture and detect protein secretion heterogeneity among cells.

LAB ON A CHIP (2021)

Article Chemistry, Analytical

An on-off fluorescent probe based on cucurbit[7]uril for highly sensitive determination of ammonia nitrogen in aquaculture water

Zhen Li et al.

Summary: A novel on-off fluorescent probe was synthesized for highly sensitive and ultra-trace determination of ammonia nitrogen in aquaculture water. The method based on the PAL@CB[7] complex and the reaction of ammonia nitrogen with formaldehyde showed high selectivity and sensitivity, promising potential for the design of on-line sensors for measuring ammonia nitrogen in aquaculture water with the integration of portable hardware systems and intelligent algorithms in the future.

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In situ SERS detection of dissolved nitrate on hydrated gold substrates

Timo Kuster et al.

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NANOSCALE ADVANCES (2021)

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Rapid nitrate determination with a portable lab-on-chip device based on double microstructured assisted reactors

Fang Wang et al.

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Lab-on-a-chip technology for in situ combined observations in oceanography

Tatsuhiro Fukuba et al.

Summary: The oceans play a crucial role in sustaining the global environment through biogeochemical processes, requiring multimodal combined observations to understand their dynamics. Developing instrumentation for in situ measurement techniques in aquatic environments remains challenging, particularly for biochemical flow analyses.

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Jiaomeng Zhu et al.

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High-Aspect-Ratio SU-8-Based Optofluidic Device for Ammonia Detection in Cell Culture Media

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Recent progress in sensing nitrate, nitrite, phosphate, and ammonium in aquatic environment

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A fully integrated passive microfluidic Lab-on-a-Chip for real-time electrochemical detection of ammonium: Sewage applications

J. Gallardo-Gonzalez et al.

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Highly reproducible and fast detection of 6-thioguanine in human serum using a droplet-based microfluidic SERS system

Wen-Shu Zhang et al.

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A Droplet Microfluidic-Based Sensor for Simultaneous in Situ Monitoring of Nitrate and Nitrite in Natural Waters

Adrian M. Nightingale et al.

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A Comprehensive Review of Microfluidic Water Quality Monitoring Sensors

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Rapid separation of post-blast explosive residues on glass electrophoresis microchips

Kemilly M. P. Pinheiro et al.

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Diurnal and seasonal variation in nitrate-nitrogen concentrations of groundwater in a saturated buffer zone

Joseph Miller et al.

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Fully Integrated, Automated, and Smartphone Enabled Point-of-Source Portable Platform With Microfluidic Device for Nitrite Detection

Sohan Dudala et al.

IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS (2019)

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Maskless, rapid manufacturing of glass microfluidic devices using a picosecond pulsed laser

Krystian L. Wlodarczyk et al.

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Lab-on-a-chip systems for photodynamic therapy investigations

Michak Chudy et al.

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Polymer Composite Optically Integrated Lab on Chip for the Detection of Ammonia

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JOURNAL OF THE ELECTROCHEMICAL SOCIETY (2018)

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Optofluidic gutter oil discrimination based on a hybrid-waveguide coupler in fibre

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Selective colorimetric detection of dissolved ammonia in water via modified Berthelot's reaction on porous paper

Yeong Beom Cho et al.

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Development of a new phase for lab-on-a-chip extraction of polycyclic aromatic hydrocarbons from water

L. Foan et al.

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Lab-on-a-chip based total-phosphorus analysis device utilizing a photocatalytic reaction

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SOLID-STATE ELECTRONICS (2018)

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Nanomaterials-based electrochemical detection of heavy metals in water: Current status, challenges and future direction

Abdul Waheed et al.

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Determination of nitrite ions in environment analysis with a paper-based microfluidic device

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Optofluidic differential colorimetry for rapid nitrite determination

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Adenosine Triphosphate Measurement in Deep Sea Using a Microfluidic Device

Tatsuhiro Fukuba et al.

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Rapid Mapping of Dissolved Methane and Carbon Dioxide in Coastal Ecosystems Using the ChemYak Autonomous Surface Vehicle

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Toward an In Situ Phosphate Sensor in Natural Waters Using a Microfluidic Flow Loop Analyzer

Yan Chen et al.

JOURNAL OF THE ELECTROCHEMICAL SOCIETY (2018)

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APPLIED WATER SCIENCE (2018)

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Recent trends in electrochemical detection of phosphate in actual waters

Claude Forano et al.

CURRENT OPINION IN ELECTROCHEMISTRY (2018)

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A Lab-on-Chip Analyzer for in Situ Measurement of Soluble Reactive Phosphate: Improved Phosphate Blue Assay and Application to Fluvial Monitoring

Geraldine S. Clinton-Bailey et al.

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Optofluidic marine phosphate detection with enhanced absorption using a Fabry-Perot resonator

J. M. Zhu et al.

LAB ON A CHIP (2017)

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Droplet control technologies for microfluidic high throughput screening (μHTS)

Muhsincan Sesen et al.

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Custom 3D printer and resin for 18 μm x 20 μm microfluidic flow channels

Hua Gong et al.

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Low Cost Lab on Chip for the Colorimetric Detection of Nitrate in Mineral Water Products

Mohammad F. Khanfar et al.

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PhosphaSense: A fully integrated, portable lab-on-a-disc device for phosphate determination in water

Gillian Duffy et al.

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Utilizing Paper-Based Devices for Antimicrobial-Resistant Bacteria Detection

Katherine E. Boehle et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

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Determination of phosphorus in natural waters: A historical review

Paul Worsfold et al.

ANALYTICA CHIMICA ACTA (2016)

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Yonghao Zhang et al.

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Towards autonomous lab-on-a-chip devices for cell phone biosensing

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Microfluidics and microbial engineering

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On-chip cavity-enhanced absorption spectroscopy using a white light-emitting diode and polymer mirrors

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Fabrication of an Amperometric Flow-Injection Microfluidic Biosensor Based on Laccase for In Situ Determination of Phenolic Compounds

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