期刊
TALANTA
卷 253, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.talanta.2022.123942
关键词
Bisphenol S; Metal-organic framework; Aptamer; Fluorescent sensor
This article introduces a "on-off-on" fluorescent sensor prepared using modified UiO-66, which can detect the content of BPS quickly and easily. The application of this sensor in commercial plastic bottled water has been validated.
Bisphenol S (BPS) is an industrial chemical that is widely used to manufacture daily items, such as plastic water bottles, milk bottles, water cups, and paper products. BPS is a biologically toxic environmental endocrine dis-ruptor. Long-term exposure to BPS can disrupt the reproductive system, endanger health, and increase the risk of cancer. The metal-organic framework UiO-66 is characterised with high thermal and chemical stability, a simple synthetic route, and low preparation cost. In this study, we modified UiO-66 with nucleic acid aptamers to prepare an 'on-off-on' fluorescent sensor for the simple and rapid detection of BPS. The FAM-labelled aptamer was selected as the fluorescent probe (i.e. 'on'). In the presence of UiO-66, the FAM-labelled aptamer adsorbed onto the surface of the UiO-66 material, and the fluorescence of FAM was quenched by photoinduced electron transfer (i.e. 'off'). When BPS was introduced into the system, the configuration of the FAM-labelled aptamer changed after binding to BPS, and the adsorption of FAM on UiO-66 weakened, resulting in fluorescence recovery (i.e. 'on').Based on this principle, the reaction system was optimised, and the BPS content was analysed according to the change in the fluorescence signal. The signals changed linearly in the BPS concentration range of 2.0 x 10-4-4.0 x 10-2 mmol L-1, and the system had a detection limit of 1.84 x 10-4 mmol L-1. The sensor was successfully used to detect the BPS content in commercial plastic bottled water.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据