4.3 Article

3-Nitro-2(1H)-quinolone derivatives as 2π components in 1,3-dipolar cycloadditions of azomethine ylides: A new synthesis of pyrrolo[3,4-c]quinolines

期刊

SYNTHETIC COMMUNICATIONS
卷 53, 期 1, 页码 76-84

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2022.2150976

关键词

Azomethine ylide; 1; 3-dipolar cycloaddition; quinoline; stereoselectivity; X-ray

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The 1,3-dipolar cycloaddition reactions between 3-nitro-2(1H)-quinolones and ester-stabilized azomethine ylides derived from sarcosine ester and various aromatic aldehydes have been extensively studied. The structure and stereochemistry of the cycloadducts were analyzed in detail using X-ray and NMR spectroscopy methods.
The 1,3-dipolar cycloaddition of 3-nitro-2(1H)-quinolones with ester-stabilized azomethine ylides derived from sarcosine ester and various aromatic aldehydes has been investigated. The structure and stereochemistry of cycloadducts were studied in detail by X-ray and NMR spectroscopy methods.

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