4.4 Article

crtrest: A command for ratio estimators of intervention effects on event rates in cluster randomized trials

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Ratio estimators of intervention effects on event rates in cluster randomized trials

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Summary: Our study investigates five estimators of intervention effects on event rates, each with different precision and power depending on the conditions, and proposes a set of unbiased estimators to control bias in studies with few clusters. The unbiased estimators perform well in simulations and are practically unbiased, while the asymptotically unbiased estimators show good performance with a larger number of clusters. Despite its simplicity, one estimator performs comparably with others in trials with a realistic number of clusters, and two estimators offer higher power in certain conditions.

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