4.8 Review

Polymerization-Induced Self-Assembly: An Emerging Tool for Generating Polymer-Based Biohybrid Nanostructures

期刊

SMALL
卷 19, 期 18, 页码 -

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.202207457

关键词

biomolecule-loaded polymeric nanostructures; biomolecule-polymer conjugates; encapsulation; grafting-from; grafting-through method; polymer-based biohybrid nanostructures; polymerization-induced self-assembly

向作者/读者索取更多资源

The combination of biomolecules and synthetic polymers offers great potential for developing innovative materials and promoting the application of biomolecules in various fields. Polymerization-induced self-assembly (PISA), as an efficient technique, allows for the fabrication of advanced polymer-based biohybrid nanostructures (PBBNs). This review presents current strategies for preparing PBBNs using the PISA technique, including grafting-from and grafting-through methods, as well as biomolecule encapsulation.
The combination of biomolecules and synthetic polymers provides an easy access to utilize advantages from both the synthetic world and nature. This is not only important for the development of novel innovative materials, but also promotes the application of biomolecules in various fields including medicine, catalysis, and water treatment, etc. Due to the rapid progress in synthesis strategies for polymer nanomaterials and deepened understanding of biomolecules' structures and functions, the construction of advanced polymer-based biohybrid nanostructures (PBBNs) becomes prospective and attainable. Polymerization-induced self-assembly (PISA), as an efficient and versatile technique in obtaining polymeric nano-objects at high concentrations, has demonstrated to be an attractive alternative to existing self-assembly procedures. Those advantages induce the focus on the fabrication of PBBNs via the PISA technique. In this review, current preparation strategies are illustrated based on the PISA technique for achieving various PBBNs, including grafting-from and grafting-through methods, as well as encapsulation of biomolecules during and subsequent to the PISA process. Finally, advantages and drawbacks are discussed in the fabrication of PBBNs via the PISA technique and obstacles are identified that need to be overcome to enable commercial application.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据