Waveguide-Enhanced Raman Spectroscopy (WERS): An Emerging Chip-Based Tool for Chemical and Biological Sensing

Photonic chip-based methods for spectroscopy are of considerable interest due to their applicability to compact, low-power devices for the detection of small molecules. Waveguide-enhanced Raman spectroscopy (WERS) has emerged over the past decade as a particularly interesting approach. WERS utilizes the evanescent field of a waveguide to generate Raman scattering from nearby analyte molecules, and then collects the scattered photons back into the waveguide. The large interacting area and strong electromagnetic field provided by the waveguide allow for significant enhancements in Raman signal over conventional approaches. The waveguide can also be coated with a molecular class-selective sorbent material to concentrate the analyte, thus further increasing the Raman signal. This review provides an overview of the historical development of WERS and highlights recent theoretical and experimental achievements with the technique.

Automated summary

Photonic chip-based waveguide-enhanced Raman spectroscopy (WERS) is an interesting method that utilizes the evanescent field of a waveguide to generate Raman scattering and collect scattered photons, leading to significant enhancements in Raman signal. Coating the waveguide with a selective sorbent material further improves the enhancement effect.