Does 7T MRI reveal a neuronal bridge between periventricular heterotopia and overlying cortical malformations?

Article Clinical Neurology

The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission

Imad Najm et al.

Summary: Ongoing challenges in diagnosing focal cortical dysplasia (FCD) require continuous research and consensus agreement to improve disease definition and classification. An International League Against Epilepsy (ILAE) Task Force has reviewed the FCD classification of 2011 and identified existing gaps. They conducted surveys, literature reviews, and clinico-pathological studies to update the classification and propose new categories. This update may contribute to a better understanding of FCD and the development of targeted treatments.

EPILEPSIA (2022)

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Article Clinical Neurology

Structural association between heterotopia and cortical lesions visualised with 7 T MRI in patients with focal epilepsy

Ariadne Zampeli et al.

Summary: This study analyzed the structural characteristics of malformations of cortical development (MCD) using 7T and 3T MRI and found that 7T MRI can reveal subtle connections between heterotopia and previously unidentified pathology in overlaying cortex.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2022)

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Article Clinical Neurology

Magnetic resonance imaging features of isolated periventricular heterotopia in pediatric epilepsy: a comparative study

Benjamin James Tittle et al.

Summary: Most radiological characteristics of periventricular nodular heterotopia are similar in patients with and without epilepsy. Only periventricular nodular heterotopia spreading across several regions was associated with a statistically higher chance of epilepsy.

EPILEPTIC DISORDERS (2022)

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Article Clinical Neurology