相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Anti-CD47 antibody treatment attenuates liver inflammation and fibrosis in experimental non-alcoholic steatohepatitis models
Taesik Gwag et al.
LIVER INTERNATIONAL (2022)
Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis
He-ming Huang et al.
ACTA PHARMACOLOGICA SINICA (2022)
Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL -mediated Necroptosis From Contributing to Liver Pathologies
Simon P. Preston et al.
GASTROENTEROLOGY (2022)
In vitro ballooned hepatocytes can be produced by primary human hepatocytes and hepatic stellate cell sheets
Nobuhiro Hasui et al.
SCIENTIFIC REPORTS (2022)
Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease
Arun J. Sanyal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans
Tatsunori Miyata et al.
JCI INSIGHT (2021)
Mechanisms and disease consequences of nonalcoholic fatty liver disease
Rohit Loomba et al.
CELL (2021)
Prospective evaluation of the prevalence of non-alcoholic fatty liver disease and steatohepatitis in a large middle-aged US cohort
Stephen A. Harrison et al.
JOURNAL OF HEPATOLOGY (2021)
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis
Junjie Yu et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Resolvin D1 promotes the targeting and clearance of necroptotic cells
Brennan D. Gerlach et al.
CELL DEATH AND DIFFERENTIATION (2020)
Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure-Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin-Mediated (hATTR) Amyloidosis
Xiaoping Zhang et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2020)
Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer
Guangyan Wei et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2020)
Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease
Amine Majdi et al.
JOURNAL OF HEPATOLOGY (2020)
Ferroptosis Affects the Progression of Nonalcoholic Steatohepatitis via the Modulation of Lipid Peroxidation-Mediated Cell Death in Mice
Jing Qi et al.
AMERICAN JOURNAL OF PATHOLOGY (2020)
Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
Bishuang Cai et al.
CELL METABOLISM (2020)
The molecular basis for current targets of NASH therapies
Kamran Qureshi et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)
Mechanisms of Fibrosis Development in NASH
Robert F. Schwabe et al.
GASTROENTEROLOGY (2020)
Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRP alpha
Brandon H. Hayes et al.
JOURNAL OF CELL SCIENCE (2020)
New drugs for non-alcoholic steatohepatitis
Ana-Carolina Cardoso et al.
LIVER INTERNATIONAL (2020)
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
Xiaobo Wang et al.
CELL METABOLISM (2020)
CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism
Hui-Chao Tao et al.
FRONTIERS IN IMMUNOLOGY (2020)
MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis
Xiaoqin Wu et al.
JOURNAL OF HEPATOLOGY (2020)
Lytic cell death in metabolic liver disease
Jeremie Gautheron et al.
JOURNAL OF HEPATOLOGY (2020)
Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis
Ping An et al.
NATURE COMMUNICATIONS (2020)
Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
Kausik K. Ray et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy
Jie Liu et al.
JCI INSIGHT (2020)
Protocol Protocol for Primary Mouse Hepatocyte Isolation
Meital Charni-Natan et al.
STAR PROTOCOLS (2020)
Efferocytosis in health and disease
Amanda C. Doran et al.
NATURE REVIEWS IMMUNOLOGY (2020)
First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers
Branimir Sikic et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology
Sho Morioka et al.
IMMUNITY (2019)
Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis
Shinya Tsurusaki et al.
CELL DEATH & DISEASE (2019)
Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences
Anqi Zhu et al.
BIOINFORMATICS (2019)
Non-alcoholic fatty liver disease - A global public health perspective
Zobair M. Younossi
JOURNAL OF HEPATOLOGY (2019)
Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap
Juri Reimand et al.
NATURE PROTOCOLS (2019)
A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis
Stephen A. Harrison et al.
JOURNAL OF HEPATOLOGY (2019)
A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice
Xiaobo Wang et al.
HEPATOLOGY COMMUNICATIONS (2019)
Necroptosis: a crucial pathogenic mediator of human disease
Mary E. Choi et al.
JCI INSIGHT (2019)
Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis
Wenli Liu et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2019)
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury
Lara Campana et al.
JOURNAL OF IMMUNOLOGY (2018)
Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice
Bing Xu et al.
JOURNAL OF HEPATOLOGY (2018)
Apoptosis and necroptosis in the liver: a matter of life and death
Robert F. Schwabe et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis
Changyu Zhu et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression
Liang Guo et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Salmon provides fast and bias-aware quantification of transcript expression
Rob Patro et al.
NATURE METHODS (2017)
Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy
Tadahiko Yanagita et al.
JCI INSIGHT (2017)
Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis
Xiaobo Wang et al.
CELL METABOLISM (2016)
Receptor interacting protein 3 protects mice from high-fat diet-induced liverinjury
Sanjoy Roychowdhury et al.
HEPATOLOGY (2016)
Thematic Review Series: Lipotoxicity: Many Roads to Cell Dysfunction and Cell Death Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis
Petra Hirsova et al.
JOURNAL OF LIPID RESEARCH (2016)
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
Elena Buzzetti et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis
Giovanni Quarato et al.
MOLECULAR CELL (2016)
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
Yoko Kojima et al.
NATURE (2016)
Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis
Marta B. Afonso et al.
CLINICAL SCIENCE (2015)
Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
Paul Angulo et al.
GASTROENTEROLOGY (2015)
CD47 Deficiency Protects Mice From Diet-induced Obesity and Improves Whole Body Glucose Tolerance and Insulin Sensitivity
Hasiyeti Maimaitiyiming et al.
SCIENTIFIC REPORTS (2015)
Necroptosis in Nonalcoholic Steatohepatitis
Jeremie Gautheron et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2015)
The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target
A. Neil Barclay et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)
A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis
Jeremie Gautheron et al.
EMBO MOLECULAR MEDICINE (2014)
Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
Tom Luedde et al.
GASTROENTEROLOGY (2014)
Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
Leszek Lisowski et al.
NATURE (2014)
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
Zhenyu Cai et al.
NATURE CELL BIOLOGY (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis
Teresa Coelho et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
Jixi Li et al.
CELL (2012)
Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis
Yury Popov et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Pan-Caspase Inhibitor VX-166 Reduces Fibrosis in an Animal Model of Nonalcoholic Steatohepatitis
Rafal P. Witek et al.
HEPATOLOGY (2009)
Inhibition of self engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
Richard K. Tsai et al.
JOURNAL OF CELL BIOLOGY (2008)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
DE Kleiner et al.
HEPATOLOGY (2005)
Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo:: Evidence for a postmitochondrial processing of caspase-8
ML Bajt et al.
TOXICOLOGICAL SCIENCES (2000)