期刊
SCHIZOPHRENIA RESEARCH
卷 251, 期 -, 页码 94-107出版社
ELSEVIER
DOI: 10.1016/j.schres.2022.12.021
关键词
Schizophrenia; Gender differences; Symptomatic remission; Functional remission; Cognition; Personal resources
类别
Gender differences in clinical and psychosocial aspects of schizophrenia have been widely studied, but the findings are inconsistent and further research is needed. This study investigated gender differences in clinical, cognitive, and functional indices in a large sample of schizophrenia patients and healthy controls. Men with schizophrenia had an earlier onset, poorer premorbid adjustment, more severe symptoms, and different coping strategies compared to women. However, these differences did not have a significant impact on overall functioning and outcome.
Gender differences in clinical and psychosocial aspects of schizophrenia have been widely reported. Findings have not always been consistent, and some of them need further research. In a large sample of community dwelling persons with schizophrenia, we investigated gender differences in clinical, cognitive and functional indices, as well as their changes over a 4-year follow-up and their impact on real-life functioning. Gender dif-ferences in personal resources, cognitive and functional indices were explored also in a sample of healthy controls. Men with respect to women had an earlier age of illness onset, a worse premorbid adjustment in the academic domain, more severe avolition, expressive deficit and positive symptoms, lower prevalence of co-morbidity for affective disorders, less frequent use of two coping strategies ('religion' and 'use of emotional support') and more frequent positive history of substance and alcohol abuse. In addition, men were more impaired in verbal learning, while women in reasoning/problem solving. Some patterns of gender differences observed in healthy controls were not confirmed in patients. Men's disadvantages in the clinical picture did not translate into a worse outcome. This finding may be related to the complex interplay of several factors acting as predictors or mediators of outcome.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据