Long-term follow-up of an IgA nephropathy cohort: outcomes and risk factors

Article Transplantation

Validation of two IgA nephropathy risk-prediction tools using a cohort with a long follow-up

Yngvar Lunde Haaskjold et al.

Summary: This study validated the accuracy of two prediction tools for IgA nephropathy, with the International IgAN Prediction Tool performing well and the IgA Nephropathy Clinical Decision Support System having some limitations.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2023)

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Article Urology & Nephrology

The effectiveness and safety of corticosteroid therapy for IgA nephropathy with crescents: a prospective, randomized, controlled study

Mengjun Liang et al.

Summary: This study evaluated the effectiveness and safety of different treatment protocols in IgA nephropathy patients with crescents. The results showed that both the 1st-3rd-5th and 1st-2nd-3rd protocols effectively reduced proteinuria and protected renal function, with the 1st-2nd-3rd protocol showing better effectiveness.

BMC NEPHROLOGY (2022)

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Article Urology & Nephrology

Distribution of kidney diseases in Joinville, Santa Catarina: analysis of a kidney biopsy data bank between 2008 and 2019

Helbert do Nascimento Lima et al.

Summary: Kidney biopsies are important for understanding the epidemiology of nephropathies. This study found that gender, age, and type of medical healthcare insurance may be associated with the occurrence of certain nephropathies.

JORNAL BRASILEIRO DE NEFROLOGIA (2022)

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Article Medicine, General & Internal

Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy The TESTING Randomized Clinical Trial

Jicheng Lv et al.

Summary: This international multicenter randomized clinical trial found that oral methylprednisolone significantly reduced the risk of kidney function decline, kidney failure, or death due to kidney disease in patients with IgA nephropathy at high risk of progression. However, it also increased the incidence of serious adverse events.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Review Medicine, General & Internal

Crescents and IgA Nephropathy: A Delicate Marriage

Hernan Trimarchi et al.

Summary: IgA nephropathy is a progressive disease with great variability in clinical course. Crescents, a distinct pathological feature, have been considered as a prognostic indicator of poor outcomes. However, recent guidelines suggest that crescents should not be used to determine disease progression or guide immunosuppression.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Urology & Nephrology

Effect of Cyclophosphamide and Glucocorticoid Therapy in IgA Nephropathy: A Single-Center Retrospective Analysis

Nicolas Beck et al.

Summary: This study suggests that immunosuppressive therapy with cyclophosphamide combined with glucocorticoids improves kidney function, proteinuria, and hematuria in IgA nephropathy patients. However, the use of steroids in patients with a higher body mass index at baseline may increase the incidence of diabetes.

KIDNEY360 (2022)

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Article Urology & Nephrology

Clinicopathological characteristics, risk factors and renal outcome in IgA nephropathy with crescents

Yiping Ruan et al.

Summary: This study investigated the clinicopathological characteristics, risk factors, and renal outcome in IgA nephropathy (IgAN) patients with crescents. The results showed that patients with crescents presented more severe clinical and pathological features. Renal function, proteinuria, and hematuria were associated with crescents, and crescents were associated with poorer renal survival, even in patients receiving immunosuppressive therapy.

JOURNAL OF NEPHROLOGY (2022)

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Article Urology & Nephrology

Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases

Brad H. Rovin et al.

Summary: This article provides an overview of the latest clinical practice guidelines for the management of glomerular diseases, aimed at assisting clinicians worldwide caring for patients with glomerulonephritis. The guidelines cover various glomerular diseases, offering guidance on diagnosis, prognosis, treatment, and special situations, as well as useful infographics and research recommendations.

KIDNEY INTERNATIONAL (2021)

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Article Urology & Nephrology

Association of Treatment Effects on Early Change in Urine Protein and Treatment Effects on GFR Slope in IgA Nephropathy: An Individual Participant Meta-analysis

Lesley A. Inker et al.

Summary: This study compared treatment effects on change in proteinuria versus change in estimated GFR slope in IgAN, finding that early reduction in proteinuria can be used as a surrogate end point for studies of chronic kidney disease progression in IgAN.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Article Urology & Nephrology

IgA Nephropathy: Core Curriculum 2021

Prapa Pattrapornpisut et al.

Summary: IgA nephropathy is the most common primary glomerular disease worldwide, with diverse clinical manifestations and ongoing research into new therapeutic options. Supportive treatment is central in initial therapy, with controversy surrounding the use of immunosuppressive agents.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Review Transplantation

Precision medicine in immunoglobulin A nephropathy: still a journey ahead

Claudia Seikrit et al.

Summary: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerular disease worldwide with complex pathophysiology and clinical presentations. Early identification and individualized therapies are crucial for predicting disease progression.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

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Review Immunology

Current treatment of IgA nephropathy

Jurgen Floege et al.

Summary: IgA nephropathy is the most common type of glomerulonephritis in Asia and the Western world. Optimal supportive care and cautious use of immunosuppression are mainstay treatments. The controversy surrounding immunosuppression and the importance of patient characteristics in treatment plans should be carefully considered.

SEMINARS IN IMMUNOPATHOLOGY (2021)

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Article Urology & Nephrology

Efficacy of corticosteroids in immunoglobulin A nephropathy with less than 25% crescents

Jingjing Chen et al.

CLINICAL AND EXPERIMENTAL NEPHROLOGY (2020)

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Article Urology & Nephrology

After ten years of follow-up, no difference between supportive care plus immunosuppression and supportive care alone in IgA nephropathy

Thomas Rauen et al.

KIDNEY INTERNATIONAL (2020)

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Article Urology & Nephrology

Improving treatment decisions using personalized risk assessment from the International IgA Nephropathy Prediction Tool

Sean J. Barbour et al.

KIDNEY INTERNATIONAL (2020)

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Article Urology & Nephrology

External Validation of the International IgA Nephropathy Prediction Tool

Junjun Zhang et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Article Urology & Nephrology

Renal survival and risk factors in IgA nephropathy with crescents

Feng Ma et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY (2020)

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Article Multidisciplinary Sciences

Crescents formations are independently associated with higher mortality in biopsy-confirmed immunoglobulin A nephropathy

Cheng-Hsu Chen et al.

PLOS ONE (2020)

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Article Multidisciplinary Sciences

Validation of the revised Oxford classification for IgA nephropathy considering treatment with corticosteroids/immunosuppressors

Takahito Moriyama et al.

SCIENTIFIC REPORTS (2020)

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Article Urology & Nephrology

Single versus dual blockade of the renin-angiotensin system in patients with IgA nephropathy

David Paul Lennartz et al.

JOURNAL OF NEPHROLOGY (2020)

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Article Medicine, General & Internal

Evaluating a New International Risk-Prediction Tool in IgA Nephropathy

Sean J. Barbour et al.

JAMA INTERNAL MEDICINE (2019)

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Article Urology & Nephrology

Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy

Aliza Thompson et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)

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Article Transplantation

Glomerular disease frequencies by race, sex and region: results from the International Kidney Biopsy Survey

Michelle M. O'Shaughnessy et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2018)

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Article Urology & Nephrology

Treatment of IgA nephropathy: Recent advances and prospects

Rosanna Coppo

NEPHROLOGIE & THERAPEUTIQUE (2018)

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Review Urology & Nephrology

Epidemiology of IgA Nephropathy: A Global Perspective

Francesco Paolo Schena et al.

SEMINARS IN NEPHROLOGY (2018)

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Article Multidisciplinary Sciences

Temporal trends in biopsy proven glomerular disease in Uruguay, 1990-2014

Mariela Garau et al.

PLOS ONE (2018)

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Article Urology & Nephrology

A Multicenter Study of the Predictive Value of Crescents in IgA Nephropathy

Mark Haas et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

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Review Urology & Nephrology

Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group

Hernan Trimarchi et al.

KIDNEY INTERNATIONAL (2017)

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Article Medicine, General & Internal

Clinical outcomes of IgA nephropathy patients with different proportions of crescents

Wang Zhang et al.

MEDICINE (2017)

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Article Pathology

Validation study of Oxford Classification of IgA Nephropathy: the significance of extracapillary hypercellularity and mesangial IgG immunostaining

Gabriel Stefan et al.

PATHOLOGY INTERNATIONAL (2016)

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Article Urology & Nephrology

Validation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments

Rosanna Coppo et al.

KIDNEY INTERNATIONAL (2014)

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Article Multidisciplinary Sciences

Prognosis in IgA Nephropathy: 30-Year Analysis of 1,012 Patients at a Single Center in Japan

Takahito Moriyama et al.

PLOS ONE (2014)

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Article Urology & Nephrology

Prediction of Outcomes in Crescentic IgA Nephropathy in a Multicenter Cohort Study

Jicheng Lv et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)

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Article Transplantation

Long-term renal survival and related risk factors in patients with IgA nephropathy: results from a cohort of 1155 cases in a Chinese adult population

WeiBo Le et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)

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Article Urology & Nephrology

Predicting the Risk for Dialysis or Death in IgA Nephropathy

Francois Berthoux et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)

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Editorial Material Urology & Nephrology

Estimating GFR Using the CKD Epidemiology Collaboration (CKD-EPI) Creatinine Equation: More Accurate GFR Estimates, Lower CKD Prevalence Estimates, and Better Risk Predictions

Andrew S. Levey et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2010)

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Article Urology & Nephrology

The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification

Daniel C. Cattran et al.

KIDNEY INTERNATIONAL (2009)

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Article Medicine, General & Internal

Glomerular diseases in a Hispanic population: review of a regional renal biopsy database

Luis Fernando Arias et al.

SAO PAULO MEDICAL JOURNAL (2009)

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Article Urology & Nephrology

Remission of proteinuria improves prognosis in IgA nephropathy

Heather N. Reich et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

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Article Transplantation

Crescentic, proliferative IgA nephropathy: clinical and histological response to methylprednisolone and intravenous cyclophosphamide

JA Tumlin et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2003)

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Article Urology & Nephrology

Regression of IgA nephropathy: A repeat biopsy study

O Hotta et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2002)

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Long-term follow-up of an IgA nephropathy cohort: outcomes and risk factors

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