4.6 Article

Investigating the ?two-hit hypothesis?: Effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Differential effects of early or late exposure to prenatal maternal immune activation on mouse embryonic neurodevelopment

Elisa Guma et al.

Summary: Exposure to maternal immune activation (MIA) during pregnancy affects embryo development, with early exposure leading to increased apoptotic cell density, and late exposure, especially in female embryos, resulting in increased neuroinflammation and oxidative stress.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)

Article Psychology, Clinical

Adolescent Cannabis Use and Adult Psychoticism: A Longitudinal Co-Twin Control Analysis Using Data From Two Cohorts

Jonathan D. Schaefer et al.

Summary: While adolescent cannabis use and cannabis use disorder are consistently associated with increased risk of psychosis, the correlation is more likely due to familial confounding factors rather than a causal effect of cannabis exposure. This suggests that efforts to reduce psychotic illnesses may benefit from focusing on other therapeutic targets.

JOURNAL OF ABNORMAL PSYCHOLOGY (2021)

Article Neurosciences

Acute Δ9-tetrahydrocannabinol prompts rapid changes in cannabinoid CB1 receptor immunolabeling and subcellular structure in CA1 hippocampus of young adult male mice

Itziar Bonilla-Del Rio et al.

Summary: The study found that acute THC exposure during early adulthood can significantly affect the expression of CB1 receptors and alter the ultrastructure of CA1. These changes may contribute to the behavioral alterations experienced by young individuals shortly after cannabis intoxication.

JOURNAL OF COMPARATIVE NEUROLOGY (2021)

Article Multidisciplinary Sciences

Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats

Samantha L. Baglot et al.

Summary: Up to a third of North Americans report using cannabis in the prior month, most commonly through inhalation. Animal models that reflect human consumption are critical to study the impact of cannabis on brain and behaviour. The study found different pharmacokinetic profiles following inhalation versus injection of THC, with higher initial brain THC concentration following inhalation.

SCIENTIFIC REPORTS (2021)

Article Neurosciences

Early or Late Gestational Exposure to Maternal Immune Activation Alters Neurodevelopmental Trajectories in Mice: An Integrated Neuroimaging, Behavioral, and Transcriptional Study

Elisa Guma et al.

Summary: This study revealed the differential effects of MIA exposure timing during pregnancy on offspring development. Early exposure resulted in accelerated brain volume increases and behavioral changes, while late exposure had less impact on anatomical and behavioral profiles.

BIOLOGICAL PSYCHIATRY (2021)

Article Cell Biology

Adolescent THC Treatment Does Not Potentiate the Behavioral Effects in Adulthood of Maternal Immune Activation

Todd M. Stollenwerk et al.

Summary: The study found that adolescent THC treatment resulted in deficits in spatial memory and enhanced spatial reversal learning in adult female mice in the Morris water maze, while exposure to MIA elicited female-specific deficits in fear extinction learning in adulthood. These effects were not observed in adult males.
Review Psychiatry

A systematic review of neuroimaging and acute cannabis exposure in age-of-risk for psychosis

Lani Cupo et al.

Summary: Acute exposure to cannabis is associated with cognitive alterations, increased risk for neuropsychiatric illness, and emergence of acute psychotic symptoms. Neuroimaging is a powerful technique to study the impact of cannabis exposure on brain structure and function in both humans and animals. Current literature indicates varied effects of cannabis exposure on the brain, but critical gaps exist in understanding sex-dependent responses and long-term effects.

TRANSLATIONAL PSYCHIATRY (2021)

Article Psychiatry

Evidence for prefrontal cortex hypofunctioning in schizophrenia through somatosensory evoked potentials

Anastasios A. Daskalakis et al.

SCHIZOPHRENIA RESEARCH (2020)

Article Psychology

Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways

Catherine Monk et al.

Annual Review of Clinical Psychology (2019)

Article Neurosciences

Cannabis and the Developing Brain: Insights into Its Long-Lasting Effects

Yasmin L. Hurd et al.

JOURNAL OF NEUROSCIENCE (2019)

Review Pharmacology & Pharmacy

The neuropsychopharmacology of cannabis: A review of human imaging studies

Michael A. P. Bloomfield et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Review Neurosciences

The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development

Heidi C. Meyer et al.

NEUROPSYCHOPHARMACOLOGY (2018)

Review Biochemistry & Molecular Biology

Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System

Shenglong Zou et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Psychiatry

Maternal Immune Activation and Neuropsychiatric Illness: A Translational Research Perspective

Alan S. Brown et al.

AMERICAN JOURNAL OF PSYCHIATRY (2018)

Article Multidisciplinary Sciences

Reversing behavioural abnormalities in mice exposed to maternal inflammation

Yeong Shin Yim et al.

NATURE (2017)

Meeting Abstract Toxicology

Dopamine: Neuropsychiatric disorders and neurotoxicity

Syed Ali et al.

TOXICOLOGY LETTERS (2017)

Review Chemistry, Multidisciplinary

Brain cannabinoid receptor 2: expression, function and modulation

De-Jie Chen et al.

ACTA PHARMACOLOGICA SINICA (2017)

Editorial Material Neurosciences

Dynamic endophenotypes and longitudinal trajectories: capturing changing aspects of development in early psychosis

Jai L. Shah et al.

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2016)

Article Biochemistry & Molecular Biology

Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons

S. Canetta et al.

MOLECULAR PSYCHIATRY (2016)

Review Multidisciplinary Sciences

Maternal immune activation: Implications for neuropsychiatric disorders

Myka L. Estes et al.

SCIENCE (2016)

Review Pharmacology & Pharmacy

The Poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery

Sonali Reisinger et al.

PHARMACOLOGY & THERAPEUTICS (2015)

Article Biochemistry & Molecular Biology

[18F]MK-9470 PET measurement of cannabinoid CB1 receptor availability in chronic cannabis users

Jenny Ceccarini et al.

ADDICTION BIOLOGY (2015)

Article Neurosciences

Changes in the Development of Striatum Are Involved in Repetitive Behavior in Autism

Marieke Langen et al.

BIOLOGICAL PSYCHIATRY (2014)

Article Neurosciences

Long-Term Effects of Cannabis on Brain Structure

Giovanni Battistella et al.

NEUROPSYCHOPHARMACOLOGY (2014)

Review Psychiatry

Cannabis and psychosis: Neurobiology

Amresh Shrivastava et al.

INDIAN JOURNAL OF PSYCHIATRY (2014)

Article Psychiatry

Changes in the adolescent brain and the pathophysiology of psychotic disorders

Matcheri S. Keshavan et al.

LANCET PSYCHIATRY (2014)

Review Psychology

Multivariate Statistical Analyses for Neuroimaging Data

Anthony R. McIntosh et al.

ANNUAL REVIEW OF PSYCHOLOGY, VOL 64 (2013)

Article Neurosciences

Abnormal Trajectories of Neurodevelopment and Behavior Following In Utero Insult in the Rat

Yael Piontkewitz et al.

BIOLOGICAL PSYCHIATRY (2011)

Article Psychology, Clinical

Longitudinal study of cognition among adolescent marijuana users over three weeks of abstinence

Karen L. Hanson et al.

ADDICTIVE BEHAVIORS (2010)

Article Neurosciences

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

Bagrat Abazyan et al.

BIOLOGICAL PSYCHIATRY (2010)

Review Pharmacology & Pharmacy

Adolescent cannabis use and psychosis: epidemiology and neurodevelopmental models

Daniel T. Malone et al.

BRITISH JOURNAL OF PHARMACOLOGY (2010)

Article Multidisciplinary Sciences

The environment and schizophrenia

Jim van Os et al.

NATURE (2010)

Review Neurosciences

Serotonin: a regulator of neuronal morphology and circuitry

Elizabeth A. Daubert et al.

TRENDS IN NEUROSCIENCES (2010)

Review Chemistry, Medicinal

Brain CB2 Receptors: Implications for Neuropsychiatric Disorders

Michelle Roche et al.

PHARMACEUTICALS (2010)

Review Pharmacology & Pharmacy

CB2 receptors in the brain: role in central immune function

G. A. Cabral et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

Article Neurosciences

Extrapolating brain development from experimental species to humans

Barbara Clancy et al.

NEUROTOXICOLOGY (2007)

Review Pharmacology & Pharmacy

The emerging functions of endocannabinoid signaling during CNS development

Tibor Harkany et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2007)

Review Biochemistry & Molecular Biology

Human cannabinoid pharmacokinetics

Marilyn A. Huestis

CHEMISTRY & BIODIVERSITY (2007)

Review Biochemistry & Molecular Biology

The neurodevelopmental model of schizophrenia: update 2005

JL Rapoport et al.

MOLECULAR PSYCHIATRY (2005)

Article Neurosciences

Nonpsychotropic cannabinoid receptors regulate microglial cell migration

L Walter et al.

JOURNAL OF NEUROSCIENCE (2003)

Article Medicine, General & Internal

Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study

L Arseneault et al.

BRITISH MEDICAL JOURNAL (2002)

Article Biochemistry & Molecular Biology

Sex steroid influence on cannabinoid CB1 receptor mRNA and endocannabinoid levels in the anterior pituitary gland

S González et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)