相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Revisiting the grammar of Tau aggregation and pathology formation: how new insights from brain pathology are shaping how we study and target Tauopathies
Galina Limorenko et al.
CHEMICAL SOCIETY REVIEWS (2022)
Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation
Lara A. Gruijs da Silva et al.
EMBO JOURNAL (2022)
Charge and redox states modulate granulin-TDP-43 coacervation toward phase separation or aggregation
Anukool A. Bhopatkar et al.
BIOPHYSICAL JOURNAL (2022)
Spatiotemporal modulations in heterotypic condensates of prion and α-synuclein control phase transitions and amyloid conversion
Aishwarya Agarwal et al.
NATURE COMMUNICATIONS (2022)
The mechanobiology of nuclear phase separation
Daniel S. W. Lee et al.
APL BIOENGINEERING (2022)
Principles Governing the Phase Separation of Multidomain Proteins
Priyesh Mohanty et al.
BIOCHEMISTRY (2022)
Sequence grammar underlying the unfolding and phase separation of globular proteins
Kiersten M. Ruff et al.
MOLECULAR CELL (2022)
A conceptual framework for understanding phase separation and addressing open questions and challenges
Tanja Mittag et al.
MOLECULAR CELL (2022)
Learning the chemical grammar of biomolecular condensates
Henry R. Kilgore et al.
NATURE CHEMICAL BIOLOGY (2022)
Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau
Pablo Gracia et al.
NATURE COMMUNICATIONS (2022)
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with alpha-Synuclein
Shailendra Dhakal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2022)
Post-translational modifications in liquid-liquid phase separation: a comprehensive review
Jingxian Li et al.
MOLECULAR BIOMEDICINE (2022)
RNA contributions to the form and function of biomolecular condensates
Christine Roden et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
The nucleolus as a multiphase liquid condensate
Denis L. J. Lafontaine et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
FUS and TDP-43 Phases in Health and Disease
Bede Portz et al.
TRENDS IN BIOCHEMICAL SCIENCES (2021)
An intrinsically disordered pathological prion variant Y145Stop converts into self-seeding amyloids via liquid-liquid phase separation
Aishwarya Agarwal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
Simon Alberti et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau
Peter E. A. Ash et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Sequence-encoded and composition-dependent protein-RNA interactions control multiphasic condensate morphologies
Taranpreet Kaur et al.
NATURE COMMUNICATIONS (2021)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
Georg Krainer et al.
NATURE COMMUNICATIONS (2021)
Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components
Ignacio Sanchez-Burgos et al.
BIOMOLECULES (2021)
Tau internalization: A complex step in tau propagation
Jianfeng Zhao et al.
AGEING RESEARCH REVIEWS (2021)
Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes
Mauro Montalbano et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2021)
Prion-like C-Terminal Domain of TDP-43 and α-Synuclein Interact Synergistically to Generate Neurotoxic Hybrid Fibrils
Shailendra Dhakal et al.
JOURNAL OF MOLECULAR BIOLOGY (2021)
Liquid-liquid phase separation of tau: From molecular biophysics to physiology and disease
Sandeep K. Rai et al.
PROTEIN SCIENCE (2021)
Structure of Tau filaments in Prion protein amyloidoses
Grace I. Hallinan et al.
ACTA NEUROPATHOLOGICA (2021)
Protein Phase Separation Arising from Intrinsic Disorder: First-Principles to Bespoke Applications
Daniel Mark Shapiro et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2021)
Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation
Jitao Wen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)
Generic nature of the condensed states of proteins
Monika Fuxreiter et al.
NATURE CELL BIOLOGY (2021)
Higher-order organization of biomolecular condensates
Charlotte M. Fare et al.
OPEN BIOLOGY (2021)
Liquid-liquid phase separation in human health and diseases
Bin Wang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
Peptide-based coacervates as biomimetic protocells
Manzar Abbas et al.
CHEMICAL SOCIETY REVIEWS (2021)
A framework for understanding the functions of biomolecular condensates across scales
Andrew S. Lyon et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
Formation of Multiphase Complex Coacervates and Partitioning of Biomolecules within them
Gregory A. Mountain et al.
BIOMACROMOLECULES (2020)
Mechanisms of secretion and spreading of pathological tau protein
Cecilia A. Brunello et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins
Grant T. Corbett et al.
ACTA NEUROPATHOLOGICA (2020)
RNA Droplets
Kevin Rhine et al.
ANNUAL REVIEW OF BIOPHYSICS, VOL 49, 2020 (2020)
Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions
Jeong-Mo Choi et al.
Annual Review of Biophysics (2020)
Multiphase Complex Coacervate Droplets
Tiemei Lu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties
Gregory L. Dignon et al.
Annual Review of Physical Chemistry (2020)
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization
David W. Sanders et al.
CELL (2020)
Composition-dependent thermodynamics of intracellular phase separation
Joshua A. Riback et al.
NATURE (2020)
Truncation of Tau selectively facilitates its pathological activities
Jianlan Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
α-Synuclein aggregation nucleates through liquid-liquid phase separation
Soumik Ray et al.
NATURE CHEMISTRY (2020)
Phase transition of RNA-protein complexes into ordered hollow condensates
Ibraheem Alshareedah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Biomolecular Condensates in the Nucleus
Benjamin R. Sabari et al.
TRENDS IN BIOCHEMICAL SCIENCES (2020)
Liquid-liquid phase separation induces pathogenic tau conformations in vitro
Nicholas M. Kanaan et al.
NATURE COMMUNICATIONS (2020)
Prion biology: implications for Alzheimer's disease therapeutics Comment
Carlo Condello et al.
LANCET NEUROLOGY (2020)
Widespread occurrence of the droplet state of proteins in the human proteome
Maarten Hardenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Regulatory mechanisms of tau protein fibrillation under the conditions of liquid-liquid phase separation
Solomiia Boyko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Liquid-Liquid Phase Separation Is Driven by Large-Scale Conformational Unwinding and Fluctuations of Intrinsically Disordered Protein Molecules
Anupa Majumdar et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2019)
Lysine/RNA-interactions drive and regulate biomolecular condensation
Tina Ukmar-Godec et al.
NATURE COMMUNICATIONS (2019)
Interplay between Short-Range Attraction and Long-Range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes
Ibraheem Alshareedah et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
Jie Wang et al.
CELL (2018)
Tau protein liquid-liquid phase separation can initiate tau aggregation
Susanne Wegmann et al.
EMBO JOURNAL (2018)
RNA buffers the phase separation behavior of prion-like RNA binding proteins
Shovamayee Maharana et al.
SCIENCE (2018)
Protein Phase Separation: A New Phase in Cell Biology
Steven Boeynaems et al.
TRENDS IN CELL BIOLOGY (2018)
Pi-Pi contacts are an overlooked protein feature relevant to phase separation
Robert McCoy Vernon et al.
ELIFE (2018)
Who's In and Who's Out-Compositional Control of Biomolecular Condensates
Jonathon A. Ditlev et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
The involvement of tau in nucleolar transcription and the stress response
Mahmoud B. Maina et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Tau pathology in Creutzfeldt-Jakob disease revisited
Gabor G. Kovacs et al.
BRAIN PATHOLOGY (2017)
Biomolecular condensates: organizers of cellular biochemistry
Salman F. Banani et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Liquid phase condensation in cell physiology and disease
Yongdae Shin et al.
SCIENCE (2017)
A role for Tau protein in maintaining ribosomal DNA stability and cytidine deaminase-deficient cell survival
Elias Bou Samra et al.
NATURE COMMUNICATIONS (2017)
Liquid-liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
Susmitha Ambadipudi et al.
NATURE COMMUNICATIONS (2017)
Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
Amayra Hernandez-Vega et al.
CELL REPORTS (2017)
Exosomes and the Prion Protein: More than One Truth
Alexander Hartmann et al.
FRONTIERS IN NEUROSCIENCE (2017)
Reentrant Phase Transition Drives Dynamic Substructure Formation in Ribonucleoprotein Droplets
Priya R. Banerjee et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder
Vladimir N. Uversky
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
Roles of tau protein in health and disease
Tong Guo et al.
ACTA NEUROPATHOLOGICA (2017)
CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins
Alex S. Holehouse et al.
BIOPHYSICAL JOURNAL (2017)
Physiological Functions of the Cellular Prion Protein
Andrew R. Castle et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2017)
Coexisting Liquid Phases Underlie Nucleolar Subcompartments
Marina Feric et al.
CELL (2016)
The Jekyll and Hyde Actions of Nucleic Acids on the Prion-like Aggregation of Proteins
Jerson L. Silva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein
Chi W. Pak et al.
MOLECULAR CELL (2016)
A Concentration-Dependent Liquid Phase Separation Can Cause Toxicity upon Increased Protein Expression
Benedetta Bolognesi et al.
CELL REPORTS (2016)
Polymer physics of intracellular phase transitions
Clifford P. Brangwynne et al.
NATURE PHYSICS (2015)
The prion protein is critical for DNA repair and cell survival after genotoxic stress
Anne Bravard et al.
NUCLEIC ACIDS RESEARCH (2015)
Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers
Mu Li et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Role of Stress Granules and RNA-Binding Proteins in Neurodegeneration: A Mini-Review
Tara Vanderweyde et al.
GERONTOLOGY (2013)
The Complex PrPc-Fyn Couples Human Oligomeric Aβ with Pathological Tau Changes in Alzheimer's Disease
Megan Larson et al.
JOURNAL OF NEUROSCIENCE (2012)
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
Eva-Maria Mandelkow et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Interactions of Prion Protein With Intracellular Proteins: So Many Partners and no Consequences?
Krzysztof Nieznanski
CELLULAR AND MOLECULAR NEUROBIOLOGY (2010)
A NH2 Tau Fragment Targets Neuronal Mitochondria at AD Synapses: Possible Implications for Neurodegeneration
Giuseppina Amadoro et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Prions: Protein Aggregation and Infectious Diseases
Adriano Aguzzi et al.
PHYSIOLOGICAL REVIEWS (2009)
Prion protein aggresomes are poly(A)+ ribonucleoprotein complexes that induce a PKR-mediated deficient cell stress response
Kevin Goggin et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)
Human tau protein forms complex with PrP and some GSS- and fCJD-related PrP mutants possess stronger binding activities with tau in vitro
Xiao-Fan Wang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
Study on interaction between microtubule associated protein tau and prion protein
Han Jun et al.
SCIENCE IN CHINA SERIES C-LIFE SCIENCES (2006)
Hyperphosphorylated tau deposition parallels prion protein burden in a case of Gerstmann-Straussier-Scheinker syndrome P102L mutation complicated with dementia
K Ishizawa et al.
ACTA NEUROPATHOLOGICA (2002)
A transmembrane form of the prion protein contains an uncleaved signal peptide and is retained in the endoplasmic reticululm
RS Stewart et al.
MOLECULAR BIOLOGY OF THE CELL (2001)