☆ 4.3 Article

Four new glycosides from Gerbera piloselloides

PHYTOCHEMISTRY LETTERS (2023)

Bioactive constituents from Gerbera piloselloides with anti-inflammatory and antiproliferative activities

Chenxu Zhao et al.

Summary: This study identified several previously undescribed compounds from the extract of Gerbera piloselloides, including some that showed inhibitory effects on nitric oxide production and cancer cell proliferation.

FITOTERAPIA (2022)

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Article Biochemistry & Molecular Biology

1H-NMR-guided isolation of enantiomeric coumarin-monoterpenes with anti-inflammatory activity from Gerbera piloselloides

Chen-xu Zhao et al.

Summary: A total of twenty-two coumarin monoterpenes were isolated from Gerbera piloselloides using 1H-NMR guided fractionation, among which fourteen were previously undescribed. Chiral phase HPLC separation successfully yielded eleven pairs of optically pure enantiomers, and their structures and absolute configurations were determined using various analytical techniques. Bioassays showed that four compounds exhibited moderate anti-inflammatory activity. Additionally, the correlations between a delta-lactone peak in the CD spectra and the structure of the compounds were reported for the first time.

PHYTOCHEMISTRY (2022)

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Article Biodiversity Conservation