期刊
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
卷 106, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ejmp.2023.102526
关键词
Cobalt-60; Compensator; IMRT; Head and neck; Global oncology
The purpose of this study is to develop a reliable and cost-effective IMRT device based on cobalt compensators, which can deliver treatment plans of equal quality to linac-MLC devices. The study evaluates the quality of treatment plans using this device.
Purpose: Our goal is to develop a novel cobalt-compensator-based IMRT device for low-and middle-income countries that is reliable and cost-effective while delivering treatment plans of equal quality to those from linac-MLC devices. The present study examines the quality of treatment plans using this device.Methods: A commercial treatment planning system (TPS; RayStation v.8B) was commissioned for this device using Monte Carlo simulations from the Geant4 toolkit. Patient-specific compensators were created as regions-of-interest. Thirty clinical head & neck cases were planned and compared to clinical plans with a 6MV linac using IMRT. The mock head and neck plan from TG-119 was used for further validation.Results: PTV objectives were achieved in all 30 plans with PTV V95% >95 %. OAR sparing was similar to clinical plans. There were 14 cases where OAR dose limits exceeded the recommended QUANTEC limits in the clinical plan in order to achieve target coverage. OAR sparing was better in the cobalt compensator plan in 8 cases and worse in 3 cases, in the latter cases exceeding the clinical plan doses by an average of 8.22 % (0.0 %-13.5 %). Average field-by-field gamma pass-rate were 93.7 % (2 %/2mm). Estimated treatment times using the Co-60 compensator device were 1 min 27 s vs 1 min 2 s for the clinical system.Conclusion: This system is the first of its kind to allow for IMRT with a Co-60 device. Data here suggests that the delivery meets plan quality criteria while maintaining short treatment times which may offer a sustainable and cost-low option for IMRT on the global scale.
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