期刊
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
卷 190, 期 -, 页码 -出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.pestbp.2022.105332
关键词
Oxidative stress; Biological parameters; Plant extract; Green synthesis; Spodoptera litura
This study investigated the multifunctional properties of Cadmium Sulphide Nanoparticles (CdS NPs) synthesized using a green synthesis method. The CdS NPs showed insecticidal, antibacterial, and anticancer activities. Ingestion of CdS NPs by larvae of Spodoptera litura resulted in dose-dependent changes in biochemical parameters and significant mortality, malformation, and reduced fertility. CdS NPs also exhibited antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus, as well as potent anticancer properties against a pancreatic cancer cell line.
The current study investigated the multifunctional properties of Cadmium Sulphide Nanoparticles synthesized using a green synthesis method (CdS NPs) using a green feedstock, Nopal Cactus fruit extract. The biological activities of the CdS NPs were thoroughly investigated, including their insecticidal, antibacterial, and anticancer activities. The different concentrations (0.005-0.04%) of CdS NPs were fed to the larvae of Spodoptera litura, and their ingestion effects were observed on the different biological, biochemical, and oxidative stress markers. There are significant dose-dependent changes in the biochemical parameters like superoxide dismutase (SOD), Catalase (CAT), Glutathione-S-transferase (GST), and MDA level as a marker of lipid peroxidation in the treated larvae were studied. In the highest concentration (0.04%), significant larval mortality (46.66%), malformation (pupae and adult) (27.78%), inhibition of adult emergence (43.87%), as well as reduced fecundity (25.28%), and fertility (22.74%) as compared to control was observed. CdS NPs have been investigated for antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus bacterial strains. In vitro anticancer activities were carried out to decrease the viability of the Pancreatic cancer cell line. The cells showed 18% and 12% viability at a 200 mu g/ml concentration when incubated with CdS NPs for 24 and 48 h, respectively, confirming its potent anticancer property. The lack of cytotoxicity against the (RBC) endorses the biocompatible nature of synthesized CdS NPs. It was observed that green synthesized CdS NPs could be used as a promising insecticidal, antibacterial, and anticancer agent.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据