4.5 Article

Neonatal Toxic Shock Syndrome-like Exanthematous Disease: A Report of Two Cases

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PEDIATRIC INFECTIOUS DISEASE JOURNAL
卷 42, 期 4, 页码 E114-E115

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0000000000003817

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newborn; Staphylococcus aureus; bacterial toxins; superantigens

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Neonatal toxic shock syndrome (TSS)-like exanthematous disease is a rare condition in neonates infected with TSS toxin-1 producing Staphylococcus aureus, characterized by rash, low platelet count, and fever. Neonatologists should be aware of this disease as it can be a possible diagnosis in neonates with rash and low platelet count. The two reported cases of Neonatal TSS-like exanthematous disease are rare in Europe.
Neonatal toxic shock syndrome (TSS)-like exanthematous disease is characterized by exanthema, thrombocytopenia and fever in neonates infected with TSS toxin-1 producing Staphylococcus aureus. Although the disease is rare, it should be known to neonatologists as it represents a differential diagnosis in neonates with exanthema and thrombocytopenia. Two presented neonates with Neonatal TSS-like exanthematous disease are rare European cases of this specific neonatal disease.

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