相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。AI and computational chemistry-accelerated development of an alotaketal analogue with conventional PKC selectivity
Jumpei Maki et al.
CHEMICAL COMMUNICATIONS (2022)
Total Synthesis and Biological Evaluation of the Potent HIV Latency-Reversing Agent Ansellone A and its Analogues
Mizushi Yanagihara et al.
ORGANIC LETTERS (2021)
Recent developments in syntheses of alotaketals and phorbaketals
Hongliang Yao et al.
TETRAHEDRON LETTERS (2020)
Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy
Clayton Hardman et al.
NATURE COMMUNICATIONS (2020)
Highly Enantioselective O-H Bond Insertion Reaction of α-Alkyl-and α-Alkenyl-α-diazoacetates with Water
You Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Au(I)-Catalyzed Cyclization of Epoxyalkynes to Allylic Alcohol Containing Spiroketals and Application to the Total Synthesis of (-)-Alotaketal A
Jaeyeon Lee et al.
ORGANIC LETTERS (2020)
Identification of protein kinase C isozymes involved in the anti-proliferative and pro-apoptotic activities of 1.0-Methyl-aplog-1, a simplified analog of debromoaplysiatoxin, in several cancer cell lines
Yusuke Hanaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Protein kinase C (PKC) isoforms in cancer, tumor promotion and tumor suppression
Noah Isakov
SEMINARS IN CANCER BIOLOGY (2018)
Total Synthesis of (-)-Phorbaketal A
Seewon Joung et al.
ORGANIC LETTERS (2017)
Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor
Alexandra C. Newton et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Rhodium(II)/Chiral Phosphoric Acid-Cocatalyzed Enantioselective O-H Bond Insertion of α-Diazo Esters
Yiliang Zhang et al.
ADVANCED SYNTHESIS & CATALYSIS (2017)
Unified Asymmetric Total Syntheses of (-)-Alotaketals A-D and (-)-Phorbaketal A
Hang Cheng et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Cancer-Associated Protein Kinase C Mutations Reveal Kinase's Role as Tumor Suppressor
Corina E. Antal et al.
CELL (2015)
Synthesis and Biological Activities of Simplified Analogs of the Natural PKC Ligands, Bryostatin-1 and Aplysiatoxin
Kazuhiro Irie et al.
CHEMICAL RECORD (2014)
Structure-Activity Studies on the Spiroketal Moiety of a Simplified Analogue of Debromoaplysiatoxin with Antiproliferative Activity
Masayuki Kikumori et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Total Synthesis of the Potent cAMP Signaling Agonist (-)-Alotaketal
Jinhua Huang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Total Synthesis of Alotaketal A
Mengyang Xuan et al.
ORGANIC LETTERS (2012)
γ-Oxygenation of α,β-Unsaturated Esters by Vinylogous O-Nitroso Mukaiyama Aldol Reaction
Guo-Qiang Tian et al.
ORGANIC LETTERS (2010)
Alotaketals A and B, Sesterterpenoids from the Marine Sponge Hamigera Species that Activate the cAMP Cell Signaling Pathway
Roberto Forestier et al.
ORGANIC LETTERS (2009)
Synthesis, conformational analysis, and biological evaluation of 1-hexylindolactam-V10 as a selective activator for novel protein kinase C isozymes
Ryo C. Yanagita et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: Bryostatin look-alikes that mimic phorbol ester function
Gary E. Keck et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Toward the development of new medicinal leads with selectivity for protein kinase C isozymes
K Irie et al.
CHEMICAL RECORD (2005)
Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains
B Ananthanarayanan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The practical synthesis of a novel and highly potent analogue of bryostatin
PA Wender et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Toward the identification of selective modulators of protein kinase C (PKC) isozymes: Establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding
M Shindo et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2001)
分享论文
