期刊
ORGANIC LETTERS
卷 24, 期 50, 页码 9194-9199出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.2c03647
关键词
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资金
- Outstanding Youth Fund of Jiangsu Province [BK20211607]
- NSFC [21702078]
- 2021 National and Provincial College Students Innovation and Entrepreneurship Training Program [202110320010Z]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- FORMAS [2019-01269]
- Swedish Research Council [2020-04764]
- Olle Engkvist Foundation
- Magnus Bergvall Foundation
- Ministry of Education and Science of the Russian Federation [075-03-2021-287/6]
- KTH Royal Institute of Technology
- Wenner-Gren Foundation
- Formas [2019-01269] Funding Source: Formas
- Swedish Research Council [2020-04764] Funding Source: Swedish Research Council
This study presents a protocol for a tandem Pd/Cu-catalyzed intermolecular cross-coupling cascade, providing a conceptually novel and controlled approach to synthesize N-fused (benzo)imidazophenanthridine scaffolds with high efficiency, broad substrate scope, and excellent functional group compatibility.
A protocol for a tandem Pd/Cu-catalyzed intermolecular cross-coupling cascade between o-bromobenzoic acids and 2-(2-bromoaryl)-1H-benzo[d]imidazoles or the corresponding imidazoles is presented. The protocol provides conceptually novel and controlled access to synthetically useful N-fused (benzo)imidazophenanthridine scaffolds with high efficiency, a broad substrate scope, and excellent functional group compatibility.
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