Three-component acyloxylation of diazo compounds with carboxylic acids and azadienes

Despite many studies on benzofuran-derived azadiene being reported, multi-component studies have scarcely been reported on this heterocyclic skeleton. The first cascade three-component acyloxylation of diazos with acids and azadienes has been reported under mild conditions. The reaction is applicable to various (A/A) diazo compounds, generating diverse complex benzofuran derivatives.

Automated summary

Despite the existence of many studies on benzofuran-derived azadienes, there have been few reports on multi-component studies on this heterocyclic skeleton. This paper presents the first cascade three-component acyloxylation of diazo compounds with acids and azadienes under mild conditions. The reaction is applicable to various (A/A) diazo compounds, resulting in the generation of diverse complex benzofuran derivatives.