4.5 Article

Plasmonic biosensor for the study of blood diseases by analysis of hemoglobin concentration

期刊

OPTICAL AND QUANTUM ELECTRONICS
卷 55, 期 3, 页码 -

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SPRINGER
DOI: 10.1007/s11082-022-04503-z

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Surface plasmon resonance; Optical sensors; Plasmons; Biosensors; Blood diseases

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Plasmonic materials and phenomena have been widely studied and applied in various fields, including the engineering of biosensor devices. Diseases of the red blood cells, such as anemia, result in abnormal reduction in hemoglobin concentration, leading to insufficient oxygen supply to tissues and organs. This numerical study aims to analyze the behavior of blood with surface plasmon resonance (SPR) and evaluate the application of SPR technique in the detection of blood diseases, specifically by studying the changes in hemoglobin concentrations (refractive index).
The plasmonic materials and phenomena are widely studies and applied in multiple fields for an extended time. One among the foremost promising applications is within the engineering of biosensor devices, Diseases of the red blood cells are among the diseases of the blood. Anemia as an example is an abnormal reduction within the concentration of hemoglobin within the blood. When the amount of red blood cells decreases, so does the concentration of hemoglobin. The tissues and organs not receive sufficient oxygen to work normally. This numerical study will give a contribution or approach on the behaviour of blood with surface plasmons resonance SPR by analysing the performance of SPR with any changes in hemoglobin concentrations (refractive index) for the application of technique in the detection of blood diseases.

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