4.6 Editorial Material

Labor Analgesia Can It Be Achieved Without an Epidural?

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Article Obstetrics & Gynecology

Meperidine Compared With Nitrous Oxide for Intrapartum Pain Relief in Multiparous Patients A Randomized Controlled Trial

Sivan Zuarez-Easton et al.

Summary: This study aimed to compare the efficacy and adverse effects of intravenous meperidine and inhaled nitrous oxide for intrapartum analgesia in multiparous patients. The results showed that there was no difference in pain intensity between the two groups 20-30 minutes after administration of the analgesics. Additionally, there were no significant differences in the need for additional analgesia, labor length, delivery mode, maternal and neonatal adverse effects, and patient satisfaction between the groups. Therefore, meperidine and nitrous oxide have similar efficacy and safety in intrapartum analgesia for multiparous patients.

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Neuraxial labor analgesia: Maintenance techniques

Elliott C. Callahan et al.

Summary: Since the introduction of neuraxial analgesia for labor, various techniques have been developed to maintain pain relief during childbirth, aiming to improve patient comfort, minimize side effects, and facilitate labor progress. Modern anesthesiologists have at their disposal techniques such as programmed intermittent epidural bolus (PIEB), patient-controlled epidural analgesia (PCEA), and dilute concentration local anesthetic + opioid epidural solutions. This article explores the historical development and evidence-based foundations of these techniques, as well as current knowledge regarding their effects on maternal-fetal health and the course of labor, along with important aspects of analgesic safety and monitoring.

BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY (2022)

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BJA EDUCATION (2020)

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Non-regional analgesia for labour: remifentanil in obstetrics

I Ronel et al.

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Past, present, and future of nitrous oxide

V. Lew et al.

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United States State-Level Variation in the Use of Neuraxial Analgesia During Labor for Pregnant Women

Alexander J. Butwick et al.

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Practice Bulletin No. 177

OBSTETRICS AND GYNECOLOGY (2017)