期刊
NUCLEIC ACIDS RESEARCH
卷 51, 期 D1, 页码 D760-D766出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkac1078
关键词
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The interpretation of 'omics data relies on well-annotated genomes. As the number of available microbial genomes increases, quality control and consistent annotation become crucial. proGenomes3 is a database containing 907,388 high-quality genomes with consistent annotation, including functional and taxonomic information.
The interpretation of genomic, transcriptomic and other microbial 'omics data is highly dependent on the availability of well-annotated genomes. As the number of publicly available microbial genomes continues to increase exponentially, the need for quality control and consistent annotation is becoming critical. We present proGenomes3, a database of 907 388 high-quality genomes containing 4 billion genes that passed stringent criteria and have been consistently annotated using multiple functional and taxonomic databases including mobile genetic elements and biosynthetic gene clusters. proGenomes3 encompasses 41 171 species-level clusters, defined based on universal single copy marker genes, for which pan-genomes and contextual habitat annotations are provided.
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