☆ 4.4 Article

Sevoflurane Preconditioning Downregulates GRIA1 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuronal Injury

NEUROTOXICITY RESEARCH (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Biochemistry & Molecular Biology

Neuroinflammation in Cerebral Ischemia and Ischemia/Reperfusion Injuries: From Pathophysiology to Therapeutic Strategies

Anamaria Jurcau et al.

Summary: Stroke is the second leading cause of death worldwide, and neuroinflammation plays a significant role in this condition. Neuroinflammation leads to tissue injury and functional recovery, and therapeutic attempts targeting neuroinflammation have been made.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Oncology

Role of microRNA-218-5p in sevoflurane-induced protective effects in hepatic ischemia/reperfusion injury mice by regulating GAB2/PI3K/AKT pathway

Hui Ji et al.

Summary: This study reveals that the inhalation anesthetic sevoflurane (Sevo) protects against hepatic ischemia/reperfusion injury (HIRI) by regulating the miR-218-5p/GAB2/PI3K/AKT pathway, reducing histologic damage, inflammatory response, oxidative stress, and apoptosis.

MOLECULAR MEDICINE REPORTS (2022)

添加到收藏夹

Article Clinical Neurology

Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke

Laura Ibanez et al.

Summary: This study aimed to determine the genetic architecture of early neurological instability after stroke. It identified eight significant loci that are associated with neurological instability, suggesting that excitotoxicity may contribute to this instability.

BRAIN (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Activation of Wnt/Beta-Catenin Signaling Pathway as a Promising Therapeutic Candidate for Cerebral Ischemia/Reperfusion Injury

Zhizhun Mo et al.

Summary: Stroke is a leading cause of death and survivors often suffer from severe neurological and motor deficits. The Wnt signaling pathway has been found to play a key role in the pathogenesis of stroke and reactivating this pathway can have significant therapeutic effects. A comprehensive understanding of the role of Wnt signaling in different cell types can help evaluate its potential value for stroke treatment.

FRONTIERS IN PHARMACOLOGY (2022)

添加到收藏夹

Article Oncology

Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway

Kai Zhang et al.

Summary: This study found that sevoflurane can protect the liver from ischemia-reperfusion (IR) injury by regulating the miR-122/Nrf2/Ho-1 pathway. Sevoflurane post-treatment or miR-122 antagomir both improved liver injury, decreased pathological damage, regulated levels of inflammatory cytokines and oxidative stress markers, and inhibited hepatocyte apoptosis. Sevoflurane post-treatment promoted the transport of Nrf2 from the cytoplasm to the nucleus and decreased the expression of miR-122 and p53.

ANNALS OF TRANSLATIONAL MEDICINE (2022)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

The Protective Effect of Sevoflurane Conditionings Against Myocardial Ischemia/Reperfusion Injury: A Systematic Review and Meta-Analysis of Preclinical Trials in in-vivo Models

Bin Hu et al.

Summary: Sevoflurane conditioning can significantly reduce infarct size in patients with myocardial ischemia/reperfusion injury. However, the controversy regarding its clinical benefits may be related to the quality and consistency of the included studies.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Oxidative Stress Underlies the Ischemia/Reperfusion-Induced Internalization and Degradation of AMPA Receptors

Lindsay M. Achzet et al.

Summary: Stroke is the fifth leading cause of death in the United States, where ischemic stroke can lead to occlusion of blood vessels supplying the brain, particularly affecting the hippocampus. Oxidative stress signaling cascade may mediate the internalization and degradation of AMPAR subunits following ischemia/reperfusion, indicating its potential vital role in cell death processes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Neuroinflammation as a Key Driver of Secondary Neurodegeneration Following Stroke?

Shannon M. Stuckey et al.

Summary: Ischaemic stroke is a leading cause of death and disability worldwide, affecting over 17 million people each year. Neuroinflammation and immune mediators play a crucial role in acute and long-term neuronal tissue damage and healing following stroke, with specific spikes in neuroinflammation observed in sites of secondary neurodegeneration. However, the exact mechanisms driving stroke-induced neuroinflammation remain poorly understood, leading to a lack of effectiveness in current anti-inflammatory treatments.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Neurosciences

GluA1-homomeric AMPA receptor in synaptic plasticity and neurological diseases

Yuan Ge et al.

Summary: Synaptic transmission is crucial for brain function, with AMPARs playing a key role in regulating the strength of synaptic transmission. Rapid trafficking of AMPARs is important for synaptic plasticity and learning, but defects in this process can lead to certain neurological disorders. Studies over the past 30 years have provided detailed insights into AMPAR trafficking mechanisms, especially highlighting the involvement of GluA1-homomeric receptors in various types of synaptic plasticity.

NEUROPHARMACOLOGY (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Sevoflurane protects the liver from ischemia-reperfusion injury by regulating Nrf2/HO-1 pathway

Hongyan Ma et al.

Summary: Sevoflurane protects the liver from ischemia-reperfusion injury by regulating the Nrf2/HO-1 pathway, reducing tissue damage and cell apoptosis, and promoting Nrf2 nucleation.

EUROPEAN JOURNAL OF PHARMACOLOGY (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Sevoflurane Postconditioning Attenuates Hepatic Ischemia-Reperfusion Injury by Limiting HMGB1/TLR4/NF-κB Pathway via Modulating microRNA-142 in vivo and in vitro

Liying Xu et al.

Summary: Sevoflurane postconditioning exerts hepatoprotective effects by inhibiting apoptosis, oxidative stress, and inflammatory response, improving survival rates in HIRI mice. Regulation of miR-142 and HMGB1 expression, as well as blocking the TLR4/NF-kappa B pathway activation, contribute to the protective effects of sevoflurane in hepatic I/R injury.

FRONTIERS IN PHARMACOLOGY (2021)

添加到收藏夹

Article Oncology

Sevoflurane pretreatment regulates abnormal expression of MicroRNAs associated with spinal cord ischemia/reperfusion injury in rats

Dan Wang et al.

Summary: Sevoflurane can regulate the expression of multiple miRNAs following SCII, particularly miR-21-5p. By affecting its target genes MAP2K3 and PPP1R3B, as well as related signaling pathways, sevoflurane may protect against SCII and exert neuroprotective effects.

ANNALS OF TRANSLATIONAL MEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal

Ischemic Stroke

Steven K. Feske

AMERICAN JOURNAL OF MEDICINE (2021)

添加到收藏夹

Review Neurosciences

Transcriptomic expression of AMPA receptor subunits and their auxiliary proteins in the human brain

Kevin Shen et al.

Summary: AMPA receptors play a crucial role in brain function and their dysregulation is linked to various diseases; studies have focused on the subunits that make up the channel and define AMPARs, but a better understanding of the diversity and regional expression of accessory proteins is needed.

NEUROSCIENCE LETTERS (2021)

添加到收藏夹

Article Neurosciences

Neuroprotection of sevoflurane against ischemia/reperfusion-induced brain injury through inhibiting GluN2A/GluN2B-PSD-95-MLK3 module

Lei Jin et al.

Summary: Sevoflurane preconditioning provides neuroprotection against cerebral ischemia-reperfusion injury by inhibiting NMDAR over-activation, reducing neuronal loss in rat hippocampal CA1 subfields.

EXPERIMENTAL BRAIN RESEARCH (2021)

添加到收藏夹

Review Medicine, Research & Experimental

Protective effects of sevoflurane in cerebral ischemia reperfusion injury: a narrative review

Tian-Yu Liang et al.

Summary: Ischemia/reperfusion (I/R) injury is a serious health threat and economic burden worldwide, causing inflammatory response, oxidative stress, brain edema, blood-brain barrier destruction, and neuronal death. Sevoflurane, an important volatile anesthetic, has been reported to reduce myocardial I/R damage, inflammation, and neuron apoptosis, offering potential neuroprotective effects against I/R injury for improved patient outcomes and quality of life.

MEDICAL GAS RESEARCH (2021)

添加到收藏夹

Review Cell Biology

Emerging role of AMPA receptor subunit GluA1 in synaptic plasticity: Implications for Alzheimer's disease

Wenrui Qu et al.

Summary: The role of GluA1-mediated synaptic plasticity in the early development of AD is well established, but the complex mechanisms involved are not fully understood. Deficits in synaptic plasticity are a central factor of AD etiology, and understanding the role of GluA1 and its regulatory mechanisms is crucial for developing disease-modifying therapies.

CELL PROLIFERATION (2021)

添加到收藏夹

Article Cell Biology

Sevoflurane Post-treatment Upregulated miR-203 Expression to Attenuate Cerebral Ischemia-Reperfusion-Induced Neuroinflammation by Targeting MyD88

Huagen Zhong et al.

INFLAMMATION (2020)

添加到收藏夹

Article Cell Biology

Sevoflurane attenuates cardiomyocyte apoptosis by mediating the miR-219a/AIM2/TLR4/MyD88 axis in myocardial ischemia/reperfusion injury in mice

Yan Li et al.

CELL CYCLE (2020)

添加到收藏夹

Article Neurosciences

An Overview on the Mechanisms of Neuroprotection and Neurotoxicity of Isoflurane and Sevoflurane in Experimental Studies

Maria-Adriana Neag et al.

BRAIN RESEARCH BULLETIN (2020)

添加到收藏夹

Article Anesthesiology

Kelch-like ECH-associated Protein 1-dependent Nuclear Factor-E2-related Factor 2 Activation in Relation to Antioxidation Induced by Sevoflurane Preconditioning

Min Cai et al.

ANESTHESIOLOGY (2017)

添加到收藏夹

Article Neurosciences

Cerebral Ischemic Preconditioning: the Road So Far...

Thushara N. Vijayakumar et al.

MOLECULAR NEUROBIOLOGY (2016)

添加到收藏夹

Article Pharmacology & Pharmacy

Sevoflurane postconditioning affects post-ischaemic myocardial mitochondrial ATP-sensitive potassium channel function and apoptosis in ageing rats

Jing-Jing Jiang et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2016)

添加到收藏夹

Review Neurosciences

Synaptic AMPA receptor composition in development, plasticity and disease

Jeremy M. Henley et al.

NATURE REVIEWS NEUROSCIENCE (2016)

添加到收藏夹

Article Neurosciences

Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury

Jocelyn Stockwell et al.

NEUROPHARMACOLOGY (2016)

添加到收藏夹

Article Anesthesiology

Activation of K2P channel-TREK1 mediates the neuroprotection induced by sevoflurane preconditioning

L. Tong et al.

BRITISH JOURNAL OF ANAESTHESIA (2014)

添加到收藏夹

Article Neurosciences

PARP-1 activation causes neuronal death in the hippocampal CA1 region by increasing the expression of Ca2+-permeable AMPA receptors

E. Gerace et al.

NEUROBIOLOGY OF DISEASE (2014)

添加到收藏夹

Article

Anesthetics, Cerebral Protection and Preconditioning

Rogean Rodrigues Nunes et al.

Revista Brasileira de Anestesiologia (2013)

添加到收藏夹

Review Neurosciences

GluA2-lacking, calcium-permeable AMPA receptors - inducers of plasticity?

Heng-Ye Man

CURRENT OPINION IN NEUROBIOLOGY (2011)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.