Akiti et al. demonstrate that dopamine in the tail of the rodent striatum predicts and regulates variability in individuals' behavioral responses to unexpected novel objects.
Mice display variability in fear-like responses to many external salient events, such as encountering unexpected novel objects, but the neural basis of this variability has been unclear. Akiti et al. (2022) demonstrate that dopamine in the tail of the rodent striatum predicts and regulates salience-related variability in individuals' behavioral responses to unexpected novel objects.
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