相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development
Yixun Su et al.
NEURON (2023)
Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis
Hideaki Nishihara et al.
BRAIN (2022)
Distinct features of brain perivascular fibroblasts and mural cells revealed by in vivo two-photon imaging
Stephanie K. Bonney et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2022)
Oligodendrocyte precursor cell transplantation promotes angiogenesis and remyelination via Wnt/beta-catenin pathway in a mouse model of middle cerebral artery occlusion
Li-Ping Wang et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2022)
Argonaute-2 protects the neurovascular unit from damage caused by systemic inflammation
Marta Machado-Pereira et al.
JOURNAL OF NEUROINFLAMMATION (2022)
Longitudinal Analysis Suggests Epstein--Barr as Cause of Multiple Sclerosis
[Anonymous]
CLINICAL PHARMACOLOGY & THERAPEUTICS (2022)
MS-Driven Metabolic Alterations Are Recapitulated in iPSC-Derived Astrocytes
Bruno Ghirotto et al.
ANNALS OF NEUROLOGY (2022)
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
Eszter Csaszar et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2022)
Increasing incidence and prevalence of multiple sclerosis in the Greater Hobart cohort of Tasmania, Australia
Steve Simpson-Yap et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)
CONCERTO: A randomized, placebo-controlled trial of oral laquinimod in relapsing-remitting multiple sclerosis
Giancarlo Comi et al.
MULTIPLE SCLEROSIS JOURNAL (2022)
Pericyte Loss Leads to Capillary Stalling Through Increased Leukocyte-Endothelial Cell Interaction in the Brain
Young-Geun Choe et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2022)
Endothelial ETS1 inhibition exacerbate blood-brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition
Yan Luo et al.
CELL DEATH & DISEASE (2022)
Direct vascular contact is a hallmark of cerebral astrocytes
Ladina Hosli et al.
CELL REPORTS (2022)
Glial-neuron crosstalk in health and disease: A focus on metabolism, obesity, and cognitive impairment
Rosemary E. Henn et al.
NEUROBIOLOGY OF DISEASE (2022)
Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod
Yasuyuki Kihara et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2022)
Using MS induced pluripotent stem cells to investigate MS aetiology
Alastair J. Fortune et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2022)
CNS Pericytes Modulate Local T Cell Infiltration in EAE
Kathrin Koch et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
Kjetil Bjornevik et al.
SCIENCE (2022)
Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-kB Signaling Pathways in Experimental Autoimmune Encephalomyelitis Mice
Lianshuang Zhang et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2021)
Astrocytes are necessary for blood-brain barrier maintenance in the adult mouse brain
Benjamin P. Heithoff et al.
GLIA (2021)
Pericytes as mediators of infiltration of macrophages in multiple sclerosis
Deepak Kumar Kaushik et al.
JOURNAL OF NEUROINFLAMMATION (2021)
Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy
Samuel A. Mills et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
CNS fibroblasts form a fibrotic scar in response to immune cell infiltration
Cayce E. Dorrier et al.
NATURE NEUROSCIENCE (2021)
Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk
Isidora Paredes et al.
NATURE NEUROSCIENCE (2021)
Pericytes regulate vascular immune homeostasis in the CNS
Orsolya Toeroek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis
Mark A. Petersen et al.
BRAIN (2021)
Digital Reconstruction of the Neuro-Glia-Vascular Architecture
Eleftherios Zisis et al.
CEREBRAL CORTEX (2021)
A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis
Martina Absinta et al.
NATURE (2021)
Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice
Kanchan Bisht et al.
NATURE COMMUNICATIONS (2021)
Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence
Sara Kohnke et al.
CELL REPORTS (2021)
Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis
Max Kaufmann et al.
MED (2021)
The active contribution of OPCs to neuroinflammation is mediated by LRP1
Anthony Fernandez-Castaneda et al.
ACTA NEUROPATHOLOGICA (2020)
High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system
Monica R. Langley et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)
Fingolimod promotes angiogenesis and attenuates ischemic brain damage via modulating microglial polarization
Ke Shang et al.
BRAIN RESEARCH (2020)
Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics
Tejasvi Dudiki et al.
NATURE COMMUNICATIONS (2020)
Nimodipine Reduces Dysfunction and Demyelination in Models of Multiple Sclerosis
Roshni A. Desai et al.
ANNALS OF NEUROLOGY (2020)
Glutamate and Nitric Oxide as biomarkers for disease activity in patients with multiple sclerosis
Maged Abdel Naseer et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2020)
Immuno-metabolic impact of the multiple sclerosis patients' sera on endothelial cells of the blood-brain barrier
M. H. Sheikh et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways
Sheng Zhang et al.
NATURE COMMUNICATIONS (2020)
Microglia in Multiple Sclerosis: Friend or Foe?
Brooke L. Guerrero et al.
FRONTIERS IN IMMUNOLOGY (2020)
Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1
Qing Shen et al.
NATURE NEUROSCIENCE (2020)
Motor learning promotes remyelination via new and surviving oligodendrocytes
Clara M. Bacmeister et al.
NATURE NEUROSCIENCE (2020)
TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering
Jin Ma et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis
Francesca Cignarella et al.
ACTA NEUROPATHOLOGICA (2020)
The Role of Cerebral Hypoperfusion in Multiple Sclerosis (ROCHIMS) Trial in Multiple Sclerosis: Insights From Negative Results
Stephanie Hostenbach et al.
FRONTIERS IN NEUROLOGY (2020)
Ablation of Vitamin D Signaling Compromises Cerebrovascular Adaptation to Carotid Artery Occlusion in Mice
Eva Pal et al.
CELLS (2020)
Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis
Laura Starost et al.
ACTA NEUROPATHOLOGICA (2020)
A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature
Erica Mondo et al.
JOURNAL OF NEUROSCIENCE (2020)
Vascular disease and multiple sclerosis: a post-mortem study exploring their relationships
Ruth Geraldes et al.
BRAIN (2020)
Neuronal regulation of the blood-brain barrier and neurovascular coupling
Luke Kaplan et al.
NATURE REVIEWS NEUROSCIENCE (2020)
The neurovascular basis of processing speed differences in humans: A model -systems approach using multiple sclerosis
Dinesh K. Sivakolundu et al.
NEUROIMAGE (2020)
A randomized, placebo-controlled, phase 2 trial of laquinimod in primary progressive multiple sclerosis
Gavin Giovannoni et al.
NEUROLOGY (2020)
iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu
Itzy E. Morales Pantoja et al.
PLOS ONE (2020)
Contractile pericytes determine the direction of blood flow at capillary junctions
Albert L. Gonzales et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Measuring the health-related quality of life in Australians with multiple sclerosis using the assessment of quality of life-8-dimension (AQoL-8D) multi-attribute utility instrument
Hasnat Ahmad et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2020)
The increasing economic burden of multiple sclerosis by disability severity in Australia in 2017: Results from updated and detailed data on types of costs
Hasnat Ahmad et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2020)
Laquinimod Modulates Human Astrocyte Function and Dampens Astrocyte-Induced Neurotoxicity during Inflammation
Emanuela Colombo et al.
MOLECULES (2020)
Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo
Sabah Mozafari et al.
SCIENCE ADVANCES (2020)
Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Is a Negative Regulator of Oligodendrocyte Progenitor Cell Differentiation in the Adult Mouse Brain
Loic Auderset et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition
Clare Walton et al.
MULTIPLE SCLEROSIS JOURNAL (2020)
Mild hypoxia triggers transient blood-brain barrier disruption: a fundamental protective role for microglia
Sebok K. Halder et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2020)
Deficiency of Complement Component C1Q Prevents Cerebrovascular Damage and White Matter Loss in a Mouse Model of Chronic Obesity
Leah C. Graham et al.
ENEURO (2020)
Neurovascular Coupling During Visual Stimulation in Multiple Sclerosis: A MEG-fMRI Study
Rachael Stickland et al.
NEUROSCIENCE (2019)
Dynamics of oligodendrocyte generation in multiple sclerosis
Maggie S. Y. Yeung et al.
NATURE (2019)
Altered human oligodendrocyte heterogeneity in multiple sclerosis
Sarah Jakel et al.
NATURE (2019)
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
Takahiro Masuda et al.
NATURE (2019)
Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
Claudio Derada Troletti et al.
CELL DEATH & DISEASE (2019)
Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation
Jianqin Niu et al.
NATURE NEUROSCIENCE (2019)
Role of Perivascular Oligodendrocyte Precursor Cells in Angiogenesis After Brain Ischemia
Natsue Kishida et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)
Disease modifying therapies continue to drive up health care cost among individuals with multiple sclerosis
Youngran Kim et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2019)
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines
Massimo Filippi et al.
BRAIN (2019)
Elevated CSF concentration of CCL3 and CCL4 in relapsing remitting multiple sclerosis patients
Mohammad Soleimani et al.
JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY (2019)
Central nervous system regeneration is driven by microglia necroptosis and repopulation
Amy F. Lloyd et al.
NATURE NEUROSCIENCE (2019)
Obesity Promotes EAE Through IL-6 and CCL-2-Mediated T Cells Infiltration
Zhe Ji et al.
FRONTIERS IN IMMUNOLOGY (2019)
The Molecular Basis for Remyelination Failure in Multiple Sclerosis
Joel Gruchot et al.
CELLS (2019)
Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination
Leslie Kirby et al.
NATURE COMMUNICATIONS (2019)
Endothelin signalling mediates experience-dependent myelination in the CNS
Matthew Swire et al.
ELIFE (2019)
Intracellular transport and regulation of transcytosis across the blood-brain barrier
Roberto Villasenor et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
Multiple Sclerosis: Destruction and Regeneration of Astrocytes in Acute Lesions
John W. Prineas et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2019)
BLOOD-BRAIN BARRIER: FROM PHYSIOLOGY TO DISEASE AND BACK
Melanie D. Sweeney et al.
PHYSIOLOGICAL REVIEWS (2019)
Dual microglia effects on blood brain barrier permeability induced by systemic inflammation
Koichiro Haruwaka et al.
NATURE COMMUNICATIONS (2019)
Astrocyte disruption of neurovascular communication is linked to cortical damage in an animal model of multiple sclerosis
Raya Eilam et al.
GLIA (2018)
Brain drains: new insights into brain clearance pathways from lymphatic biology
Neil I. Bower et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2018)
Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension
Raja Kapoor et al.
LANCET NEUROLOGY (2018)
Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria
Alan J. Thompson et al.
LANCET NEUROLOGY (2018)
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system
Axel Montagne et al.
NATURE MEDICINE (2018)
Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
Wendy Klement et al.
NEUROBIOLOGY OF DISEASE (2018)
A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter
Takakuni Maki et al.
STEM CELLS (2018)
Multiple Sclerosis Pathology
Hans Lassmann
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2018)
Effect of Vitamin D Supplementation on Markers of Vascular Function: A Systematic Review and Individual Participant Meta-Analysis
Louise A. Beveridge et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)
The Role of Astrocytes in Multiple Sclerosis
Gerald Ponath et al.
FRONTIERS IN IMMUNOLOGY (2018)
Cerebral Blood Flow Changes in Multiple Sclerosis and Neuromyelitis Optica and Their Correlations With Clinical Disability
Xue Zhang et al.
FRONTIERS IN NEUROLOGY (2018)
A molecular atlas of cell types and zonation in the brain vasculature
Michael Vanlandewijck et al.
NATURE (2018)
Administration of an antagonist of P2X7 receptor to EAE rats prevents a decrease of expression of claudin-5 in cerebral capillaries
Tomasz Grygorowicz et al.
PURINERGIC SIGNALLING (2018)
Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
Ana Mendanha Falcao et al.
NATURE MEDICINE (2018)
How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?
Renee E. Pepper et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
An updated histological classification system for multiple sclerosis lesions
Tanja Kuhlmann et al.
ACTA NEUROPATHOLOGICA (2017)
Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology
Gerald Ponath et al.
BRAIN (2017)
Distribution of cardiac output to the brain across the adult lifespan
Chang-Yang Xing et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)
The capillary bed offers the largest hemodynamic resistance to the cortical blood supply
Ian Gopal Gould et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2017)
Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion?
Si-Qi Du et al.
MOLECULAR NEUROBIOLOGY (2017)
Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis
Tomas Olsson et al.
NATURE REVIEWS NEUROLOGY (2017)
Astrocytic tight junctions control inflammatory CNS lesion pathogenesis
Sam Horng et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
Thomas A. Longden et al.
NATURE NEUROSCIENCE (2017)
The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years
Sergio E. Baranzini et al.
TRENDS IN GENETICS (2017)
Brain Pericytes As Mediators of Neuroinflammation
Justin Rustenhoven et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression
Chenhui Wang et al.
NATURE COMMUNICATIONS (2017)
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
Alerie Guzman De La Fuente et al.
CELL REPORTS (2017)
Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination
Ellen Iacobaeus et al.
STEM CELLS TRANSLATIONAL MEDICINE (2017)
The impact of vitamin D supplement intake on vascular endothelial function; a systematic review and meta-analysis of randomized controlled trials
Mohsen Mazidi et al.
FOOD & NUTRITION RESEARCH (2017)
Smoking and multiple sclerosis: A systematic review and meta-analysis using the Bradford Hill criteria for causation
Michelle L. Degelman et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2017)
Effects of fumarates on inflammatory human astrocyte responses and oligodendrocyte differentiation
Dylan A. Galloway et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2017)
The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes
Melanie S. Brennan et al.
SCIENTIFIC REPORTS (2017)
Soluble epoxide hydrolase inhibition Promotes White Matter Integrity and Long-Term Functional Recovery after chronic hypoperfusion in mice
Yuxue Chen et al.
SCIENTIFIC REPORTS (2017)
Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology
Gerald Ponath et al.
BRAIN (2017)
Fibrin(ogen) and Neurodegeneration in the Progressive Multiple Sclerosis Cortex
Richard L. Yates et al.
ANNALS OF NEUROLOGY (2017)
Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis
Tobias Zrzavy et al.
BRAIN (2017)
Assessment of Early Evidence of Multiple Sclerosis in a Prospective Study of Asymptomatic High-Risk Family Members
Zongqi Xia et al.
JAMA NEUROLOGY (2017)
Genes and Environment in Multiple Sclerosis project: A platform to investigate multiple sclerosis risk
Zongqi Xia et al.
ANNALS OF NEUROLOGY (2016)
What is a pericyte?
David Attwell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)
Multiple sclerosis: clinical profiling and data collection as prerequisite for personalized medicine approach
Tjalf Ziemssen et al.
BMC NEUROLOGY (2016)
Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events The Framingham Heart Study
Leroy L. Cooper et al.
CIRCULATION-CARDIOVASCULAR IMAGING (2016)
Neurovascular coupling in patients with relapsing-remitting multiple sclerosis
Gulnur Tekgol Uzuner et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2016)
Cerebral blood flow modulation insufficiency in brain networks in multiple sclerosis: A hypercapnia MRI study
Olga Marshall et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)
The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting
Christopher S. von Bartheld et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2016)
Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial
Fred Lublin et al.
LANCET (2016)
Regional reduction in cortical blood flow among cognitively impaired adults with relapsing-remitting multiple sclerosis patients
Seyed-Parsa Hojjat et al.
MULTIPLE SCLEROSIS JOURNAL (2016)
Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles
Anusha Mishra et al.
NATURE NEUROSCIENCE (2016)
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor
Joel Kaye et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system
Sueli Marques et al.
SCIENCE (2016)
Oligodendrocyte precursors migrate along vasculature in the developing nervous system
Hui-Hsin Tsai et al.
SCIENCE (2016)
Regional reduction in cortical blood flow among cognitively impaired adults with relapsing-remitting multiple sclerosis patients
Seyed-Parsa Hojjat et al.
MULTIPLE SCLEROSIS JOURNAL (2016)
Gray Matter Hypoxia in the Brain of the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis
Thomas W. Johnson et al.
PLOS ONE (2016)
Obesity and Arterial Stiffness in Children Systematic Review and Meta-Analysis
Anita T. Cote et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)
Permeability of the blood-brain barrier predicts conversion from optic neuritis to multiple sclerosis
Stig P. Cramer et al.
BRAIN (2015)
Genome-wide significant association with seven novel multiple sclerosis risk loci
Christina M. Lill et al.
JOURNAL OF MEDICAL GENETICS (2015)
Shift work influences multiple sclerosis risk
A. K. Hedstrom et al.
MULTIPLE SCLEROSIS JOURNAL (2015)
Focal disturbances in the blood-brain barrier are associated with formation of neuroinflammatory lesions
Jorge Ivan Alvarez et al.
NEUROBIOLOGY OF DISEASE (2015)
Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
Axel Montagne et al.
NEURON (2015)
Potential interactions between pericytes and oligodendrocyte precursor cells in perivascular regions of cerebral white matter
Takakuni Maki et al.
NEUROSCIENCE LETTERS (2015)
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
Jae Kyu Ryu et al.
NATURE COMMUNICATIONS (2015)
Reduced cortical microvascular oxygenation in multiple sclerosis: a blinded, case-controlled study using a novel quantitative near-infrared spectroscopy method
Runze Yang et al.
SCIENTIFIC REPORTS (2015)
Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation
Natalya Korogod et al.
ELIFE (2015)
Shift work influences multiple sclerosis risk
A. K. Hedstrom et al.
MULTIPLE SCLEROSIS JOURNAL (2015)
Dimethyl fumarate in the treatment of relapsing-remitting multiple sclerosis: an overview
Roberto Bomprezzi
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2015)
Efficacy and safety of delayed-release dimethyl fumarate in patients newly diagnosed with relapsing-remitting multiple sclerosis (RRMS)
Ralf Gold et al.
MULTIPLE SCLEROSIS JOURNAL (2015)
Flow regulation of endothelin-1 production in the inner medullary collecting duct
Meghana M. Pandit et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2015)
Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis
Tracy J. Yuen et al.
CELL (2014)
Sepsis Is Associated With Altered Cerebral Microcirculation and Tissue Hypoxia in Experimental Peritonitis
Fabio Silvio Taccone et al.
CRITICAL CARE MEDICINE (2014)
Insulin Action in Brain Regulates Systemic Metabolism and Brain Function
Andre Kleinridders et al.
DIABETES (2014)
Fingolimod: A Review of Its Use in Relapsing-Remitting Multiple Sclerosis
Mark Sanford
DRUGS (2014)
Lipopolysaccharide Activates Toll-like Receptor 4 (TLR4)-mediated NF-κB Signaling Pathway and Proinflammatory Response in Human Pericytes
Irene Guijarro-Munoz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia
Hannah X. Chu et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)
The Extracellular Matrix Protein Laminin α2 Regulates the Maturation and Function of the Blood-Brain Barrier
Michael J. Menezes et al.
JOURNAL OF NEUROSCIENCE (2014)
Adult Neural Precursor Cells from the Subventricular Zone Contribute Significantly to Oligodendrocyte Regeneration and Remyelination
Yao Lulu Xing et al.
JOURNAL OF NEUROSCIENCE (2014)
The analysis of correlation between IL-1B gene expression and genotyping in multiple sclerosis patients
Masoumeh Heidary et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2014)
Capillary pericytes regulate cerebral blood flow in health and disease
Catherine N. Hall et al.
NATURE (2014)
Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden
Julie Staals et al.
NEUROLOGY (2014)
Oligodendrocyte Precursor Cells Support Blood-Brain Barrier Integrity via TGF-β Signaling
Ji Hae Seo et al.
PLOS ONE (2014)
Neuronal organization of olfactory bulb circuits
Shin Nagayama et al.
FRONTIERS IN NEURAL CIRCUITS (2014)
Immunoevasive Pericytes From Human Pluripotent Stem Cells Preferentially Modulate Induction of Allogeneic Regulatory T Cells
Hagit Domev et al.
STEM CELLS TRANSLATIONAL MEDICINE (2014)
A Critical Role for the Vascular Endothelium in Functional Neurovascular Coupling in the Brain
Brenda R. Chen et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2014)
Impaired Cerebrovascular Reactivity in Multiple Sclerosis
Olga Marshall et al.
JAMA NEUROLOGY (2014)
Abnormal blood-brain barrier permeability in normal appearing white matter in multiple sclerosis investigated by MRI
S. P. Cramer et al.
NEUROIMAGE-CLINICAL (2014)
Robust Perfusion Deficits in Cognitively Impaired Patients with Secondary-Progressive Multiple Sclerosis
P. L. Francis et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2013)
Neurological Deficits Caused by Tissue Hypoxia in Neuroinflammatory Disease
Andrew L. Davies et al.
ANNALS OF NEUROLOGY (2013)
Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination
Thomas Skripuletz et al.
BRAIN (2013)
Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination
Tracy J. Yuen et al.
BRAIN (2013)
Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis
Valerie Jolivel et al.
BRAIN (2013)
Postischemic Brain Infiltration of Leukocyte Subpopulations Differs among Murine Permanent and Transient Focal Cerebral Ischemia Models
Wei Zhou et al.
BRAIN PATHOLOGY (2013)
Blocking LINGO-1 as a Therapy to Promote CNS Repair: From Concept to the Clinic
Sha Mi et al.
CNS DRUGS (2013)
Netrin 1 contributes to vascular remodeling in the subventricular zone and promotes progenitor emigration after demyelination
Myriam Cayre et al.
DEVELOPMENT (2013)
Temporal Profile of Astrocytes and Changes of Oligodendrocyte-Based Myelin Following Middle Cerebral Artery Occlusion in Diabetic and Non-diabetic Rats
Li Jing et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2013)
Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO
Tobias Stubbe et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2013)
Heterogeneity of cortical lesions in multiple sclerosis: an MRI perfusion study
Denis Peruzzo et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2013)
Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude
Ruth Dobson et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2013)
Childhood Obesity and Cardiovascular Dysfunction
Anita T. Cote et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)
Childhood body mass index and multiple sclerosis risk: a long-term cohort study
Kassandra L. Munger et al.
MULTIPLE SCLEROSIS JOURNAL (2013)
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
Veronique E. Miron et al.
NATURE NEUROSCIENCE (2013)
Cerebral hypoperfusion in multiple sclerosis is reversible and mediated by endothelin-1
Miguel D'haeseleer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects
Nikolaos A. Patsopoulos et al.
PLOS GENETICS (2013)
Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination
Wolfgang Brueck et al.
ACTA NEUROPATHOLOGICA (2012)
Kinetics of Proinflammatory Monocytes in a Model of Multiple Sclerosis and Its Perturbation by Laquinimod
Manoj K. Mishra et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Laminin regulates postnatal oligodendrocyte production by promoting oligodendrocyte progenitor survival in the subventricular zone
Jenne Relucio et al.
GLIA (2012)
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
Azeb Tadesse Argaw et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Serum nitric oxide concentrations in patients with multiple sclerosis and patients with epilepsy
Saida Ibragic et al.
JOURNAL OF NEURAL TRANSMISSION (2012)
Age at onset as a determinant of presenting phenotype and initial relapse recovery in multiple sclerosis
M. Cossburn et al.
MULTIPLE SCLEROSIS JOURNAL (2012)
High body mass index before age 20 is associated with increased risk for multiple sclerosis in both men and women
Anna K. Hedstrom et al.
MULTIPLE SCLEROSIS JOURNAL (2012)
Metabolic Modulation of Cytokine-Induced Brain Endothelial Adhesion Molecule Expression
Ganta Vijay Chaitanya et al.
MICROCIRCULATION (2012)
Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis
Giancarlo Comi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Laquinimod, a Quinoline-3-Carboxamide, Induces Type II Myeloid Cells That Modulate Central Nervous System Autoimmunity
Ulf Schulze-Topphoff et al.
PLOS ONE (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
Dimitrios Davalos et al.
NATURE COMMUNICATIONS (2012)
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation
Anny-Claude Luissint et al.
FLUIDS AND BARRIERS OF THE CNS (2012)
Multiple sclerosis normal-appearing white matter: Pathology-imaging correlations
Natalia M. Moll et al.
ANNALS OF NEUROLOGY (2011)
Human Placental Pericytes Poorly Stimulate and Actively Regulate Allogeneic CD4 T Cell Responses
Cheryl L. Maier et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
Ralf A. Linker et al.
BRAIN (2011)
Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
Annika Armulik et al.
DEVELOPMENTAL CELL (2011)
Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide
Andrej Kovac et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate
Johanne E. Rinholm et al.
JOURNAL OF NEUROSCIENCE (2011)
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid
Samia Ragheb et al.
MULTIPLE SCLEROSIS JOURNAL (2011)
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
Ji Woong Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cigarette Smoke Components Induce Matrix Metalloproteinase-1 in Aortic Endothelial Cells through Inhibition of mTOR Signaling
Vincent Lemaitre et al.
TOXICOLOGICAL SCIENCES (2011)
Gene expression analysis of the microvascular compartment in multiple sclerosis using laser microdissected blood vessels
Paula Cunnea et al.
ACTA NEUROPATHOLOGICA (2010)
Astrocytes: biology and pathology
Michael V. Sofroniew et al.
ACTA NEUROPATHOLOGICA (2010)
CNS Elevation of Vascular and Not Mucosal Addressin Cell Adhesion Molecules in Patients with Multiple Sclerosis
Rachel Allavena et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Glatiramer Acetate A Review of its Use in Relapsing-Remitting Multiple Sclerosis and in Delaying the Onset of Clinically Definite Multiple Sclerosis
Natalie J. Carter et al.
DRUGS (2010)
The Perivascular Astroglial Sheath Provides a Complete Covering of the Brain Microvessels: An Electron Microscopic 3D Reconstruction
Thomas Misje Mathiisen et al.
GLIA (2010)
Sphingosine 1-Phosphate Receptor 1 and 3 Are Upregulated in Multiple Sclerosis Lesions
Ruben Van Doorn et al.
GLIA (2010)
Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis
Zizhen Kang et al.
IMMUNITY (2010)
NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease
Richa B. Tripathi et al.
JOURNAL OF NEUROSCIENCE (2010)
Pericytes regulate the blood-brain barrier
Annika Armulik et al.
NATURE (2010)
Pericytes are required for blood-brain barrier integrity during embryogenesis
Richard Daneman et al.
NATURE (2010)
Longitudinal Examination of Obesity and Cognitive Function: Results from the Baltimore Longitudinal Study of Aging
John Gunstad et al.
NEUROEPIDEMIOLOGY (2010)
Increased blood vessel density and endothelial cell proliferation in multiple sclerosis cerebral white matter
Janet E. Holley et al.
NEUROSCIENCE LETTERS (2010)
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
Ludwig Kappos et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Promotion of Central Nervous System Remyelination by Induced Differentiation of Oligodendrocyte Precursor Cells
Sha Mi et al.
ANNALS OF NEUROLOGY (2009)
An Oligovascular Niche: Cerebral Endothelial Cells Promote the Survival and Proliferation of Oligodendrocyte Precursor Cells
Ken Arai et al.
JOURNAL OF NEUROSCIENCE (2009)
Biochemical Evidence of Atherosclerosis Progression Mediated by Increased Oxidative Stress in Apolipoprotein E-Deficient Spontaneously Hyperlipidemic Mice Exposed to Chronic Cigarette Smoke
Masaru Kunitomo et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2009)
White matter hemodynamic abnormalities precede sub-cortical gray matter changes in multiple sclerosis
Andrew W. Varga et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2009)
Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex
Leda Dimou et al.
JOURNAL OF NEUROSCIENCE (2008)
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Ludwig Kappos et al.
LANCET (2008)
PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
Leanne E. Rivers et al.
NATURE NEUROSCIENCE (2008)
NG2 cells generate both oligodendrocytes and gray matter astrocytes
Xiaoqin Zhu et al.
DEVELOPMENT (2008)
Mid-life adiposity factors relate to blood-brain barrier integrity in late life
D. R. Gustafson et al.
JOURNAL OF INTERNAL MEDICINE (2007)
Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?
Christina Marik et al.
BRAIN (2007)
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors
Florian Mullershausen et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Obesity impairs vascular relaxation in human subjects: hyperglycemia exaggerates drenergic vasoconstriction - Arterial dysfunction in obesity and diabetes
William I. Sivitz et al.
JOURNAL OF DIABETES AND ITS COMPLICATIONS (2007)
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis
T. Misu et al.
BRAIN (2007)
Persistent endothelial abnormalities and blood-brain barrier leak in primary and secondary progressive multiple sclerosis
S. Leech et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2007)
Glatiramer acetate in primary progressive multiple sclerosis: Results of a multinational, multicenter, double-blind, placebo-controlled trial
Jerry S. Wolinsky et al.
ANNALS OF NEUROLOGY (2007)
Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation
Zsuzsanna Orosz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
Kassandra L. Munger et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Pattern of hemodynamic impairment in multiple sclerosis: Dynamic susceptibility contrast perfusion MR imaging at 3.0 T
Sumita Adhya et al.
NEUROIMAGE (2006)
Low cerebrospinal fluid insulin levels in obese humans
W. Kern et al.
DIABETOLOGIA (2006)
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
CH Polman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis
CMP Vos et al.
NEUROBIOLOGY OF DISEASE (2005)
Blocking adhesion molecules as therapy for multiple sclerosis: Natalizumab
L Steinman
NATURE REVIEWS DRUG DISCOVERY (2005)
Temporal relationship between elevation of Epstein-Barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis
LI Levin et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
Differential activation of astrocytes by innate and adaptive immune stimuli
PA Carpentier et al.
GLIA (2005)
Pulsatile flow increases the expression of eNOS, ET-1, and prostacyclin in a novel in vitro coculture model of the retinal vasculature
TE Walshe et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
M Krumbholz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor
S Raab et al.
THROMBOSIS AND HAEMOSTASIS (2004)
Induction of IL-10 in rat peritoneal macrophages and dendritic cells by glatiramer acetate
S Jung et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
Peroxynitrite-mediated oxidative modification of low-density lipoprotein by aqueous extracts of cigarette smoke and the preventive effect of fluvastatin
Y Yamaguchi et al.
ATHEROSCLEROSIS (2004)
Vitamin D intake and incidence of multiple sclerosis
KL Munger et al.
NEUROLOGY (2004)
Microvascular abnormality in relapsing-remitting multiple sclerosis: Perfusion MR imaging findings in normal-appearing white matter
M Law et al.
RADIOLOGY (2004)
Asynchronous shear stress and circumferential strain reduces endothelial NO synthase and cyclooxygenase-2 but induces endothelin-1 gene expression in endothelial cells
MB Dancu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Cortical GABA interneurons in neurovascular coupling: Relays for subcortical vasoactive pathways
B Cauli et al.
JOURNAL OF NEUROSCIENCE (2004)
Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
DC Darland et al.
DEVELOPMENTAL BIOLOGY (2003)
Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination
J Kirk et al.
JOURNAL OF PATHOLOGY (2003)
Epidemiology of smoking-induced cardiovascular disease
DM Burns
PROGRESS IN CARDIOVASCULAR DISEASES (2003)
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
H Gerhardt et al.
JOURNAL OF CELL BIOLOGY (2003)
Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis
AI Danilov et al.
JOURNAL OF NEUROIMMUNOLOGY (2003)
Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases
F Aboul-Enein et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Why does remyelination fail in multiple sclerosis?
RJM Franklin
NATURE REVIEWS NEUROSCIENCE (2002)
Stable expression of angiopoietin-1 and other markers by cultured pericytes: Phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo
C Sundberg et al.
LABORATORY INVESTIGATION (2002)
Glatiramer acetate and IFN-β act on dendritic cells in multiple sclerosis
Y Hussien et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
An energy budget for signaling in the grey matter of the brain
D Attwell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
JW Peterson et al.
ANNALS OF NEUROLOGY (2001)
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
JGN Garcia et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Antiproliferative properties of sphingosine-1-phosphate in human hepatic myofibroblasts
A Pébay et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis
G Matarese et al.
JOURNAL OF IMMUNOLOGY (2001)
European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging-measured disease activity and burden in patients with relapsing multiple sclerosis
G Comi et al.
ANNALS OF NEUROLOGY (2001)
Plasma interleukin-6, tumour necrosis factor α and blood cytokine production in type 2 diabetes
JC Pickup et al.
LIFE SCIENCES (2000)
Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
Q Zhou et al.
NEURON (2000)
Sonic hedgehog-regulateld oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system
QR Lu et al.
NEURON (2000)