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A first step towards preventive medicine in multiple sclerosis

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NATURE REVIEWS NEUROLOGY
卷 19, 期 3, 页码 134-135

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NATURE PORTFOLIO
DOI: 10.1038/s41582-022-00769-9

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The first randomized, placebo-controlled trial of dimethyl fumarate in radiologically isolated syndrome patients demonstrated its efficacy in reducing the risk of a first clinical demyelinating event. These findings provide a foundation for preventive medicine in multiple sclerosis and underscore the importance of precise risk prognostication.
The results of the first randomized, placebo-controlled trial of dimethyl fumarate in a cohort of participants with radiologically isolated syndrome showed efficacy against the risk of a first clinical demyelinating event. The findings pave the way for preventive medicine in multiple sclerosis and highlight the need for more precise prognostication of risk.

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