Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome

The post-acute sequelae of COVID-19 present major problems for many patients, their physicians and the health-care system. They are unrelated to the severity of the initial infection, are often highly symptomatic and can occur after vaccination. Many sequelae involve cardiovascular autonomic dysfunction, with postural orthostatic tachycardia syndrome in 30% of individuals. Prognosis is unknown, and treatment is still unsatisfactory.

Automated summary

The post-acute sequelae of COVID-19 pose significant challenges for patients, physicians, and the healthcare system. These sequelae are not dependent on the severity of the initial infection, often exhibit pronounced symptoms, and can even occur after vaccination. Many cases involve cardiovascular autonomic dysfunction, with 30% of individuals experiencing postural orthostatic tachycardia syndrome. The prognosis remains uncertain, and treatment options are still inadequate.