期刊
NATURAL PRODUCT RESEARCH
卷 37, 期 18, 页码 3152-3157出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2022.2146686
关键词
Ginsenoside Rd; p-MLC20; MLCK; IBS
The aim of this study is to investigate the effects of ginsenoside Rd on intestinal contractility and related mechanisms in IBS.
Irritable bowel syndrome (IBS) is a very common refractory disease. Its exact pathophysiological mechanism is still unclear. Despite the availability of plentiful drugs to control IBS, most patients do not respond well. Ginsenoside Rd is one of the major active components of Panax ginseng, which has been verified to produce various pharmacological actions. However, the role of ginsenoside Rd in modulating smooth muscle contractility is still undefined. The aim of this study is to investigate the effects of ginsenoside Rd on intestinal contractility and related mechanisms in IBS.
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