4.3 Article

Curcumin-Nicotinate Attenuates Hippocampal Synaptogenesis Dysfunction in Hyperlipidemia Rats by the BDNF/TrkB/CREB Pathway: Involving Idol/LDLR Signaling to Eliminate Aβ Deposition

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Curcumin nicotinate decreases serum LDL cholesterol through LDL receptor-mediated mechanism

Caiping Zhang et al.

Summary: Curcumin nicotinate (Curtn) can decrease serum LDL-C levels by inhibiting PCSK9 expression, increasing LDL receptor expression and distribution.

EUROPEAN JOURNAL OF PHARMACOLOGY (2022)

Review Cell Biology

Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

Angelika Wieckowska-Gacek et al.

Summary: The studies suggest that an excess of saturated fatty acids and simple sugars in the diet is a known environmental risk factor of Alzheimer's disease. The systemic alterations induced by a Western diet, including metabolic changes, obesity, inflammation, may drive impairment of the blood-brain barrier and neuroinflammation, leading to neurodegeneration and cognitive impairment.

AGEING RESEARCH REVIEWS (2021)

Review Medical Laboratory Technology

Cholesterol in LDL receptor recycling and degradation

Hui-xian Yang et al.

CLINICA CHIMICA ACTA (2020)

Article Biochemistry & Molecular Biology

Therapeutic IDOL Reduction Ameliorates Amyloidosis and Improves Cognitive Function in APP/PS1 Mice

Jie Gao et al.

MOLECULAR AND CELLULAR BIOLOGY (2020)

Article Neurosciences

Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy

Li-Tao Yi et al.

NEUROBIOLOGY OF DISEASE (2020)

Article Endocrinology & Metabolism

High-fat diet induces time-dependent synaptic plasticity of the lateral hypothalamus

Victoria Linehan et al.

MOLECULAR METABOLISM (2020)

Article Medicine, Research & Experimental

Nanoemulsions improve the efficacy of turmeric in palmitate- and high fat diet-induced cellular and animal models

Eun Ji Lee et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Neurosciences

Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels

Shangxi Xiao et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)

Article Agriculture, Multidisciplinary

Curcumin Protects against Atherosclerosis in Apolipoprotein E-Knockout Mice by Inhibiting Toll-like Receptor 4 Expression

Shanshan Zhang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)

Review Neurosciences

Protective Effects of Indian Spice Curcumin Against Amyloid-beta in Alzheimer's Disease

P. Hemachandra Reddy et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Article Neurosciences

Microglia CREB-Phosphorylation Mediates Amyloid-β-Induced Neuronal Toxicity

Yuan Gao et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

Article Cell Biology

A BDNF-Mediated Push-Pull Plasticity Mechanism for Synaptic Clustering

Dragos Niculescu et al.

CELL REPORTS (2018)

Review Food Science & Technology

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

Betul Kocaadam et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2017)

Article Biochemistry & Molecular Biology

Interaction of amyloid- (A) oligomers with neurexin 2 and neuroligin 1 mediates synapse damage and memory loss in mice

Jordano Brito-Moreira et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Geriatrics & Gerontology

Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer's disease

Fernanda G. De Felice et al.

FRONTIERS IN AGING NEUROSCIENCE (2015)

Review Neurosciences

AMPA-silent synapses in brain development and pathology

Eric Hanse et al.

NATURE REVIEWS NEUROSCIENCE (2013)

Review Neurosciences

Neurotrophin regulation of neural circuit development and function

Hyungju Park et al.

NATURE REVIEWS NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis

Joseph M. Castellano et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Neurosciences

The CREB1-BDNF-NTRK2 Pathway in Depression: Multiple Gene-Cognition-Environment Interactions

Gabriella Juhasz et al.

BIOLOGICAL PSYCHIATRY (2011)

Article Biochemistry & Molecular Biology

The E3 Ubiquitin Ligase IDOL Induces the Degradation of the Low Density Lipoprotein Receptor Family Members VLDLR and ApoER2

Cynthia Hong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Geriatrics & Gerontology

High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

Carl Julien et al.

NEUROBIOLOGY OF AGING (2010)

Article Neurosciences

PSD-95 regulates synaptic transmission and plasticity in rat cerebral cortex

JC Béïque et al.

JOURNAL OF PHYSIOLOGY-LONDON (2003)