期刊
MOLECULES
卷 27, 期 23, 页码 -出版社
MDPI
DOI: 10.3390/molecules27238599
关键词
electrochemical enzyme sensor; metal-organic layers; horseradish peroxidase; hydrogen peroxide
资金
- National Natural Science Foundation of China
- [22078273]
- [21776233]
Using two-dimensional metal-organic layers (MOLs) as electron transfer mediators helps to enhance the sensitivity, reproducibility, and stability of redox enzyme-based sensors.
Metal-organic frames (MOFs) have recently been used to support redox enzymes for highly sensitive and selective chemical sensors for small biomolecules such as oxygen (O-2), hydrogen peroxide (H2O2), etc. However, most MOFs are insulative and their three-dimensional (3D) porous structures hinder the electron transfer pathway between the current collector and the redox enzyme molecules. In order to facilitate electron transfer, here we adopt two-dimensional (2D) metal-organic layers (MOLs) to support the HRP molecules in the detection of H2O2. The correlation between the current response and the H2O2 concentration presents a linear range from 7.5 mu M to 1500 mu M with a detection limit of 0.87 mu M (S/N = 3). The sensitivity, reproducibility, and stability of the enzyme sensor are promoted due to the facilitated electron transfer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据