Recent Trends in Multiclass Analysis of Emerging Endocrine Disrupting Contaminants (EDCs) in Drinking Water

Article Chemistry, Applied

Method development using chemometric tools for determination of endocrine-disrupting chemicals in bottled mineral waters

Mikhael P. M. Vivas et al.

Summary: A simple method based on d-mu-SPE and LC-MS was developed to determine 14 EDCs in bottled waters. DMP and BPA were found in samples, with concentrations exceeding safe intake limits.

FOOD CHEMISTRY (2022)

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Article Multidisciplinary Sciences

From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures

Nicolo Caporale et al.

Summary: This study found that exposure to EDC mixtures during early pregnancy is associated with language delay in offspring. The experimental results showed that at human-relevant concentrations, this mixture disrupts hormone-regulated and disease-relevant regulatory networks in the brain, as well as behavioral responses. Reanalyzing epidemiological data, it was found that up to 54% of children had prenatal exposures above experimentally derived levels of concern, resulting in a 3.3 times higher risk of language delay compared to the lowest decile of exposure.

SCIENCE (2022)

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Article Biochemical Research Methods

A novel workflow for semi-quantification of emerging contaminants in environmental samples analyzed by LC-HRMS

Reza Aalizadeh et al.

Summary: A semi-quantitative analysis method is proposed for newly identified substances in environmental samples, utilizing ionization efficiency measurement and predictive modeling. The method has been applied and tested in real environmental seawater samples.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

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Article Environmental Sciences

A Framework for Utilizing High-Resolution Mass Spectrometry and Non-targeted Analysis in Rapid Response and Emergency Situations

Allison L. Phillips et al.

Summary: Unknown chemical releases are a major focus of rapid response scenarios for the US Environmental Protection Agency. Recent advancements in high-resolution mass spectrometry and non-targeted analysis have significantly improved the ability to identify unknown compounds quickly and effectively, making them highly relevant in rapid response situations. This article advocates for the consideration of high-resolution mass spectrometry-based non-targeted analysis approaches to support future rapid response needs.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2022)

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Article Environmental Sciences

Towards regulation of Endocrine Disrupting chemicals (EDCs) in water resources using bioassays - A guide to developing a testing strategy

Julie Robitaille et al.

Summary: This paper discusses the hazards of endocrine disrupting chemicals (EDCs) in water resources, the potential bioassays for screening EDCs, advantages and limitations of sample preparation methods, and provides several key recommendations.

ENVIRONMENTAL RESEARCH (2022)

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Article Environmental Sciences

An introduction to the sources, fate, occurrence and effects of endocrine disrupting chemicals released into the environment

C. D. Metcalfe et al.

Summary: This article discusses the sources and fate of selected endocrine disrupting chemicals (EDCs) in the environment. It focuses on the classes of compounds that disrupt the endocrine system of vertebrate and invertebrate organisms. The article highlights the fate of EDCs in environmental media where there is a clear link between exposure and endocrine effects in humans or other taxa.

ENVIRONMENTAL RESEARCH (2022)

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Article Engineering, Environmental

Pharmaceuticals, hormones, plasticizers, and pesticides in drinking water

Sze Yee Wee et al.

Summary: The study developed an analytical method for quantifying multiclass EDCs in drinking water with significant variations in concentration observed between field samples. Daily exposure to EDCs through drinking water is unlikely to pose a health risk.

JOURNAL OF HAZARDOUS MATERIALS (2022)

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Article Biochemistry & Molecular Biology

Use of Passive and Grab Sampling and High-Resolution Mass Spectrometry for Non-Targeted Analysis of Emerging Contaminants and Their Semi-Quantification in Water

Dorde Tadic et al.

Summary: In recent years, various groups of organic micropollutants, including pharmaceuticals and pesticides, have emerged in the environment, leading to increased environmental and human health risks. To assess these risks, it is important to determine the occurrence of these pollutants in the environment. Therefore, many studies have focused on improving the extraction efficiency of organic micropollutants from different environmental matrices, as well as their detection parameters and acquisition modes using mass spectrometry. This paper presents different sampling methodologies and high-resolution mass spectrometry-based non-target screening workflows for the identification of pharmaceuticals, pesticides, and their transformation products in different types of water. Through the application of a passive sampling technique, 85 and 47 contaminants were identified in wastewater effluent and river water, respectively. Prioritization of contaminants was also conducted through semi-quantification in grab samples for monitoring schemes.

MOLECULES (2022)

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Article Chemistry, Analytical

Assessment of automated off-line solid-phase extraction LC-MS/MS to monitor EPA priority endocrine disruptors in tap water, surface water, and wastewater

Ken Goeury et al.

Summary: This study evaluated the suitability of automated off-line solid phase extraction liquid chromatography tandem mass spectrometry for the determination of EPA-priority endocrine-disrupting compounds in environmental water matrixes. Factors that may influence the analytical performance were assessed, and various materials and protocol variations were tested. The method showed acceptable extraction efficiencies and reliable limits of detection for the target compounds in different water samples. Method validation confirmed the accuracy and precision of the method through linearity, accuracy, and precision tests in reagent water and matrix-matched extracted calibrants.

TALANTA (2022)

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Review Engineering, Environmental

Source, fate, transport and modelling of selected emerging contaminants in the aquatic environment: Current status and future perspectives

Xuneng Tong et al.

Summary: This study reviews and discusses the modeling of emerging contaminants in aquatic environments, critically evaluating the principles, mathematical derivations, development, and applications of various models. Recommendations for improving data quality, monitoring planning, model development, and applications are also provided. The outcomes of this review can lay down a future framework for a comprehensive modeling approach to effectively manage water resources impacted by rising levels of emerging contaminants.

WATER RESEARCH (2022)

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Article Multidisciplinary Sciences

Occurrence and seasonal disparity of emerging endocrine disrupting chemicals in a drinking water supply system and associated health risk

Manoj Kumawat et al.

Summary: Contamination of drinking water with endocrine-disrupting chemicals (EDCs) raises concerns over water security and human exposure. This study investigated the seasonal disparity and occurrence of six phthalates and bisphenol-A in the drinking water supply system, and assessed the associated health risks. The results showed significant seasonal variations in PAEs concentration, with higher levels in winter and lower levels in summer. DEHP concentrations exceeded the permissible limit, suggesting a potential health risk. The findings highlight the need for immediate scrutiny of EDCs in drinking water supply systems to ensure water quality and human health.

SCIENTIFIC REPORTS (2022)

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Article Chemistry, Applied

Miniaturized solid-phase microextraction coupled with gas chromatography-mass spectrometry for determination of endocrine disruptors in drinking water

Mereke Alimzhanova et al.

Summary: A simple and rapid method based on miniaturized solid-phase microextraction (mini-SPME) followed by gas chromatography-mass spectrometry was developed to identify eight endocrine disruptors in drinking water samples. The method showed high sensitivity and accuracy, and can be used for qualitative and quantitative analysis of analytes at extremely low concentrations.

FOOD CHEMISTRY-X (2022)

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Article Engineering, Chemical

Drinking water consumption and association between actual and perceived risks of endocrine disrupting compounds

Sze Yee Wee et al.

Summary: This study investigated drinking water consumption patterns among consumers of different life stages, evaluated household practices using tap water as daily drinking water, and examined the actual risk as well as consumers' perception of tap water quality for drinking with the potential EDCs contamination. The study is important for supporting risk communication and governance strategies and promoting public participation in the development of drinking water supply system.

NPJ CLEAN WATER (2022)

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Article Multidisciplinary Sciences

A guide to the organ-on-a-chip

Chak Ming Leung et al.

Summary: This article introduces the basic concepts, applications, and development trends of organ-on-chip (OoC) technology, as well as factors to consider when developing application-specific OoCs.

NATURE REVIEWS METHODS PRIMERS (2022)

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Review Environmental Sciences

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Suzanne E. Fenton et al.

Summary: Reports on the impacts of per- and polyfluoroalkyl substances (PFAS) on the environment and human health have increased substantially in peer-reviewed literature. Epidemiological studies have shown associations between exposure to specific PFAS and various health effects, and further research is needed to understand differences in responses between sexes, species, and life stages. More contemporary approaches such as read-across, molecular dynamics, and protein modeling are proposed to accelerate the development of toxicity information on PFAS, as well as the need for precaution to protect human health given the known effects of certain PFAS compounds.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2021)

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Article Environmental Sciences

Occurrence, spatial distribution and risk assessment of high concern endocrine-disrupting chemicals in Jiangsu Province, China

Deling Fan et al.

Summary: This study quantified and evaluated the environmental risk of EDCs in Jiangsu Province, China using high-resolution mass spectrometry, revealing high concentrations of nonylphenol, 4-tert-octylphenol, and (2-ethylhexyl)phthalate in surface water. The risk assessment indicated that DEHP posed a high risk in all samples, with the highest risk quotient reaching 54.7. The study provides valuable insights into the occurrence and distribution of EDCs in Jiangsu Province.

CHEMOSPHERE (2021)

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Article Environmental Sciences

In vitro effects-based method and water quality screening model for use in pre- and post-distribution treated waters

Elizabeth Medlock Kakaley et al.

Summary: This study tested 49 water samples from the Chicago Department of Water Management service areas and found estrogenic and androgenic activity in untreated Lake Michigan intake water samples. A tiered screening approach was proposed to increase sample screening speed for samples with anticipated low-level activity.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

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Review Endocrinology & Metabolism

Thyroid Disrupting Effects of Old and New Generation PFAS

Francesca Coperchini et al.

Summary: PFAS are synthetic compounds widely used in industry due to their properties, but are potentially dangerous for human health and the environment. New generation PFAS have replaced some old generation PFAS in order to be safer. Concerns exist about the adverse effects of PFAS on the thyroid gland and human health.

FRONTIERS IN ENDOCRINOLOGY (2021)

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Article Environmental Sciences

Tap water contamination: Multiclass endocrine disrupting compounds in different housing types in an urban settlement

Sze Yee Wee et al.

Summary: The study analyzed 18 multiclass EDCs in tap water from different housing types and found higher concentrations of bisphenol A in high-rise housing. The distribution of caffeine and sulfamethoxazole in tap water varied significantly between different housing types, with higher salinity and conductivity in high-rise housings compared to landed housings. There were no potential health risks of EDCs estimated in different age groups via drinking water intake.

CHEMOSPHERE (2021)

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Review Pharmacology & Pharmacy

Organ-on-a-chip technology for the study of the female reproductive system

Rachel E. Young et al.

Summary: Organs-on-a-chip and microphysiological systems have emerged as disruptive in vitro technologies, offering new capabilities to engineer physiological living tissues and organ units. Recent progress in the development of microengineered female reproductive organ models has relevance to drug delivery and discovery, with applications in the study of pregnancy, infertility, and reproductive diseases.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Article Environmental Sciences

Suspect screening workflow comparison for the analysis of organic xenobiotics in environmental water samples

B. Gonzalez-Gaya et al.

Summary: Suspect screening techniques can determine a wider range of compounds than traditional target analysis, but the performance relies on peak annotation procedures. A study compared four workflows using different suspect lists, revealing that while differences were observed at lower confidence levels, only 4 features were annotated differently among the workflows. The approach based on the mzCloud library provided satisfactory results with a simpler method for analyzing organic xenobiotics in environmental water samples.

CHEMOSPHERE (2021)

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Article Biochemical Research Methods

Development and implementation of an analytical procedure for the quantification of natural and synthetic steroid hormones in whole surface waters

E. Mirmont et al.

Summary: Natural and synthetic steroid hormones are released into aquatic environments, and a sensitive multi-residue analytical strategy was developed in this study to quantify 23 steroid hormones in surface waters. The method showed satisfactory recoveries and measurement errors for most compounds, with limits of quantification achieved for the majority of target compounds. The procedure was successfully implemented in a monitoring survey of Belgian surface waters, detecting contamination by certain steroid hormones at low levels.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2021)

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Article Chemistry, Analytical

Non-targeted screening of trace organic contaminants in surface waters by a multi-tool approach based on combinatorial analysis of tandem mass spectra and open access databases

Emmanuel Eysseric et al.

Summary: Non-targeted screening in mass spectrometry helps overcome the limitations of targeted analysis by detecting concerning compounds not monitored and using in silico tools to identify contaminants at ultra-trace levels, revealing new trends in surface water contamination.

TALANTA (2021)

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Article Chemistry, Analytical

Assessment of emerging polar organic pollutants linked to contaminant pathways within an urban estuary using non-targeted analysis

Kirsten E. Overdahl et al.

Summary: A comprehensive analysis of polar organic pollutants in water samples from San Francisco Bay using HR/AM mass spectrometry identified approximately 6350 compounds, with 424 tentatively identified. Sources of organic pollutants included urban stormwater runoff, wastewater effluent, and agricultural runoff.

ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS (2021)

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Article Water Resources

How Perceptions of Trust, Risk, Tap Water Quality, and Salience Characterize Drinking Water Choices

Madeline A. Grupper et al.

Summary: This study examined the relationships between managers and communities in influencing in-home drinking water behavior in Roanoke Virginia. Findings showed that individuals who drink more tap water have higher trust in water managers, evaluate water quality more positively, perceive lower risks, and pay less attention to changes in tap water. Utility managers can use residents' drinking water behavior as a tool to inform future interactions with the public, aiming to enhance resilience and adaptability to external water supply threats.

HYDROLOGY (2021)

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Review Chemistry, Analytical

From Pesticides to Per- and Polyfluoroalkyl Substances: An Evaluation of Recent Targeted and Untargeted Mass Spectrometry Methods for Xenobiotics

James N. Dodds et al.

ANALYTICAL CHEMISTRY (2021)

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Article Environmental Sciences

De Facto Water Reuse: Bioassay suite approach delivers depth and breadth in endocrine active compound detection

Elizabeth K. Medlock Kakaley et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2020)

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Article Biochemical Research Methods

Development of a Multiresidue Method for Endocrine-Disrupting Pesticides by Solid Phase Extraction and Determination by UHPLC-MS/MS from Drinking Water Samples

Shaoying Liu et al.

JOURNAL OF CHROMATOGRAPHIC SCIENCE (2020)

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Article Engineering, Environmental

Wide-scope target screening of > 2000 emerging contaminants in wastewater samples with UPLC-Q-ToF-HRIVIS/MS and smart evaluation of its performance through the validation of 195 selected representative analytes

Pablo Gago-Ferrero et al.

JOURNAL OF HAZARDOUS MATERIALS (2020)

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Article Chemistry, Analytical

Rapid analysis of 4-nonylphenol by solid phase microextraction in water samples

Karla Vargas-Berrones et al.

TALANTA (2020)

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Letter Environmental Sciences

Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment

Elina Drakvik et al.

ENVIRONMENT INTERNATIONAL (2020)

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Review Endocrinology & Metabolism

Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

Bayram Yilmaz et al.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2020)

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Article Multidisciplinary Sciences

Trace identification of endocrine-disrupting bisphenol A in drinking water by solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry

Ahmad Moid AlAmmari et al.

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2020)

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Article Environmental Sciences

The potential endocrine disruption of pesticide transformation products (TPs): The blind spot of pesticide risk assessment

Chenyang Ji et al.

ENVIRONMENT INTERNATIONAL (2020)

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Article Endocrinology & Metabolism

BPA and risk assessment

Antonia M Calafat et al.

Lancet Diabetes & Endocrinology (2020)

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Article Biochemical Research Methods

A polymeric solid-phase microextraction fiber for the detection of pharmaceuticals in water samples

Yuwei Wang et al.

JOURNAL OF CHROMATOGRAPHY A (2020)

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Review Biotechnology & Applied Microbiology

Recent advances in the analysis of per- and polyfluoroalkyl substances (PFAS)-A review

Md Al Amin et al.

ENVIRONMENTAL TECHNOLOGY & INNOVATION (2020)

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Article Environmental Sciences

Grouping of endocrine disrupting chemicals for mixture risk assessment - Evidence from a rat study

Sofie Christiansen et al.

ENVIRONMENT INTERNATIONAL (2020)

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Article Environmental Sciences

Mixed organic and inorganic tapwater exposures and potential effects in greater Chicago area, USA

Paul M. Bradley et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2020)

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Article Multidisciplinary Sciences

Occurrence of multiclass endocrine disrupting compounds in a drinking water supply system and associated risks

Sze Yee Wee et al.

SCIENTIFIC REPORTS (2020)

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Article Environmental Sciences

Public Awareness and Risk Perceptions of Endocrine Disrupting Chemicals: A Qualitative Study

Melissa Kelly et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

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Article Environmental Sciences

Towards a harmonized method for the global reconnaissance of multi-class antimicrobials and other pharmaceuticals in wastewater and receiving surface waters

Randolph R. Singh et al.

ENVIRONMENT INTERNATIONAL (2019)

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Article Engineering, Environmental

Hormones and Pharmaceuticals in Groundwater Used As a Source of Drinking Water Across the United States

Laura M. Bexfield et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2019)

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Review Environmental Sciences

Organophosphate flame retardants (OPFRs): A review on analytical methods and occurrence in wastewater and aquatic environment

Ioanna Pantelaki et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

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Article Chemistry, Analytical

Optimization of a DI-SPME-GC-MS/MS method for multi-residue analysis of pesticides in waters

Y. Jabali et al.

MICROCHEMICAL JOURNAL (2019)

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Article Environmental Sciences

Occurrence and risk assessment of multiclass endocrine disrupting compounds in an urban tropical river and a proposed risk management and monitoring framework

Sze Yee Wee et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

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Article Biochemical Research Methods

EPA's non-targeted analysis collaborative trial (ENTACT): genesis, design, and initial findings

Elin M. Ulrich et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)

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Article Biochemical Research Methods

Analysis of Environmental Protection Agency priority endocrine disruptor hormones and bisphenol A in tap, surface and wastewater by online concentration liquid chromatography tandem mass spectrometry

Ken Goeury et al.

JOURNAL OF CHROMATOGRAPHY A (2019)

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Review Engineering, Chemical

Occurrence and public-perceived risk of endocrine disrupting compounds in drinking water

Sze Yee Wee et al.

NPJ CLEAN WATER (2019)

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Review Engineering, Biomedical

Organ-on-a-Chip Systems for Women's Health Applications

Janna Nawroth et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Biochemical Research Methods

Evaluation of on-line concentration coupled to liquid chromatography tandem mass spectrometry for the quantification of neonicotinoids and fipronil in surface water and tap water

Juan Manuel Montiel-Leon et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2018)

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Editorial Material Multidisciplinary Sciences

Regulate to reduce chemical mixture risk

Andreas Kortenkamp et al.

SCIENCE (2018)

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Article Environmental Sciences

Environmentally Relevant Chemical Mixtures of Concern in Waters of United States Tributaries to the Great Lakes

Sarah M. Elliott et al.

INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT (2018)

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Article Engineering, Environmental

Emerging Pollutants–Part I: Occurrence, Fate and Transport

Yanting Zhao et al.

WATER ENVIRONMENT RESEARCH (2018)

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Review Chemistry, Analytical

Water Analysis: Emerging Contaminants and Current Issues

Susan D. Richardson et al.

ANALYTICAL CHEMISTRY (2018)

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Article Chemistry, Analytical

Optimization and Application of a GC-MS Method for the Determination of Endocrine Disruptor Compounds in Natural Water

Jose Gustavo Ronderos-Lara et al.

SEPARATIONS (2018)

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Article Environmental Sciences

Simultaneous Detection of 13 Endocrine Disrupting Chemicals in Water by a Combination of SPE-BSTFA Derivatization and GC-MS in Transboundary Rivers (France-Belgium)

Rafika Ben Sghaier et al.

WATER AIR AND SOIL POLLUTION (2017)

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Article Environmental Sciences

Impact of untreated wastewater on a major European river evaluated with a combination of in vitro bioassays and chemical analysis

Maria Koenig et al.

ENVIRONMENTAL POLLUTION (2017)

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Article Environmental Sciences

Association between perceptions of public drinking water quality and actual drinking water quality: A community-based exploratory study in Newfoundland (Canada)

Benjamin Ochoo et al.

ENVIRONMENTAL RESEARCH (2017)

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Review Food Science & Technology

Human exposure to chemical mixtures: Challenges for the integration of toxicology with epidemiology data in risk assessment

Antonio F. Hernandez et al.

FOOD AND CHEMICAL TOXICOLOGY (2017)

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Article Environmental Sciences

Nationwide reconnaissance of contaminants of emerging concern in source and treated drinking waters of the United States

Susan T. Glassmeyer et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2017)

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Article Environmental Sciences

Nationwide reconnaissance of contaminants of emerging concern in source and treated drinking waters of the United States: Pharmaceuticals

Edward T. Furlong et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2017)

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Article Multidisciplinary Sciences

A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle

Shuo Xiao et al.

NATURE COMMUNICATIONS (2017)

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Article Environmental Sciences

Endocrine Disruptors and Pregnancy: Knowledge, Attitudes and Prevention Behaviors of French Women

Steeve Rouillon et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2017)

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Article Biology

What is an endocrine disruptor?

Claude Monneret

COMPTES RENDUS BIOLOGIES (2017)

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Article Environmental Sciences

Endocrine-disrupting activity of per- and polyfluoroalkyl substances: Exploring combined approaches of ligand and structure based modeling

Supratik Kar et al.

CHEMOSPHERE (2017)

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Review Biochemical Research Methods

Organ-on-a-chip for assessing environmental toxicants

Soohee Cho et al.

CURRENT OPINION IN BIOTECHNOLOGY (2017)

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Article Environmental Sciences

Evidence of estrogenic endocrine disruption in smallmouth and largemouth bass inhabiting Northeast US national wildlife refuge waters: A reconnaissance study

L. R. Iwanowicz et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2016)

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Article Environmental Sciences

Estrogenic effects in the influents and effluents of the drinking water treatment plants

Yan-You Gou et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2016)

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Review Chemistry, Analytical

Endocrine disrupting compounds (EDCs) in environmental matrices: Review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds

Tuan Fauzan Tuan Omar et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)

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Review Chemistry, Analytical

Modern trends in solid phase extraction: New sorbent media

Justyna Plotka-Wasylka et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)

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Review Chemistry, Analytical

Analytical tools monitoring endocrine disrupting chemicals

Viviana Scognamiglio et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)

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Review Chemistry, Analytical

A critical review of solid phase microextraction for analysis of water samples

Hamed Piri-Moghadam et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)

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Review Chemistry, Multidisciplinary

Risk assessment of environmental mixture effects

Kelly A. Heys et al.

RSC ADVANCES (2016)

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Article Engineering, Environmental

Extended Suspect and Non-Target Strategies to Characterize Emerging Polar Organic Contaminants in Raw Wastewater with LC-HRMS/MS

Pablo Gago-Ferrero et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2015)

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Article Biodiversity Conservation

Human Risk Assessment for Nonylphenol

Thomas G. Osimitz et al.

HUMAN AND ECOLOGICAL RISK ASSESSMENT (2015)

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Review Engineering, Environmental

Why endocrine disrupting chemicals (EDCs) challenge traditional risk assessment and how to respond

Vivian Futran Fuhrman et al.

JOURNAL OF HAZARDOUS MATERIALS (2015)

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Review Chemistry, Multidisciplinary

A review of what is an emerging contaminant

Sebastien Sauve et al.

CHEMISTRY CENTRAL JOURNAL (2014)

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Article Pharmacology & Pharmacy

Low dose mixture effects of endocrine disrupters and their implications for regulatory thresholds in chemical risk assessment

Andreas Kortenkamp

CURRENT OPINION IN PHARMACOLOGY (2014)

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Editorial Material Engineering, Environmental

Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence

Emma L. Schymanski et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2014)

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Article Biochemical Research Methods

Trace analysis of endocrine disrupting compounds in environmental water samples by use of solid-phase extraction and gas chromatography with mass spectrometry detection

Abdelmonaim Azzouz et al.

JOURNAL OF CHROMATOGRAPHY A (2014)

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Article Chemistry, Multidisciplinary

Ultra high performance liquid chromatography tandem mass spectrometry for rapid analysis of trace organic contaminants in water

Tarun Anumol et al.

CHEMISTRY CENTRAL JOURNAL (2013)

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Review Environmental Sciences

Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals

Daniel M. Rotroff et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2013)

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Article Chemistry, Analytical

Simultaneous determination of 76 micropollutants in water samples by headspace solid phase microextraction and gas chromatography-mass spectrometry

C. Martinez et al.

TALANTA (2013)

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Review Food Science & Technology

Human Risk Assessment of Endocrine-Disrupting Chemicals Derived from Plastic Food Containers

Du Yeon Bang et al.

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2012)

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Article Biochemical Research Methods

Identification strategy for unknown pollutants using high-resolution mass spectrometry: Androgen-disrupting compounds identified through effect-directed analysis

Jana M. Weiss et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2011)

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Review Biochemistry & Molecular Biology

Endocrine disrupting chemicals and other substances of concern in food contact materials: An updated review of exposure, effect and risk assessment

Jane Muncke

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2011)

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Article Environmental Sciences

Endocrine disruptor screening: regulatory perspectives and needs

Markus Hecker et al.

Environmental Sciences Europe (2011)

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Review Environmental Sciences

Endocrine disrupting pesticides: implications for risk assessment

R. McKinlay et al.

ENVIRONMENT INTERNATIONAL (2008)

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