Copper-Catalyzed Difluoroalkylation Reaction

This review describes recent advances in copper-catalyzed difluoroalkylation reactions. The RCF2 radical is generally proposed in the mechanism of these reactions. At present, various types of copper-catalyzed difluoroalkylation reactions have been realized. According to their characteristics, we classify these difluoroalkylation reactions into three types.

Automated summary

This review summarizes recent advances in copper-catalyzed difluoroalkylation reactions and classifies them into three types based on their characteristics.