Vertical and horizontal gene transfer tradeoffs direct plasmid fitness

Article Biology

Translational demand is not a major source of plasmid-associated fitness costs

Jeronimo Rodriguez-Beltran et al.

Summary: Limiting translation efficiency does not increase the fitness costs of plasmids, suggesting that ribosomal paucity is not a major driver of plasmid fitness costs.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2022)

添加到收藏夹

Article Microbiology

The Role of Antibiotic Resistance Genes in the Fitness Cost of Multiresistance Plasmids

Fredrika Rajer et al.

Summary: Multiresistance plasmids have evolutionary advantage in antibiotic treatment environments and impose fitness costs on bacteria. This study investigates the contribution of plasmid-borne resistance genes to bacterial fitness and finds that particular resistance genes are responsible for the cost of the plasmid.

MBIO (2022)

添加到收藏夹

Review Microbiology

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

Jeronimo Rodriguez-Beltran et al.

Summary: Plasmids play a vital role in bacterial ecology and evolution by mobilizing accessory genes through horizontal gene transfer. Recent studies show that plasmids, kept at multiple copies per cell, create islands of polyploidy in bacterial genomes, leading to evolution governed by different rules than those affecting chromosomal genes. Plasmids may accelerate bacterial evolution by promoting the evolution of plasmid-encoded genes and enhancing the adaptation of their host chromosomes.

NATURE REVIEWS MICROBIOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Conjugation dynamics depend on both the plasmid acquisition cost and the fitness cost

Hannah Prensky et al.

Summary: The process of plasmid acquisition during conjugation results in immediate but transient metabolic perturbation. This study found that newly acquired transconjugants exhibit slower growth and prolonged lag times compared to cells that have been replicating for several generations, indicating the presence of a plasmid acquisition cost. The short-term effects of plasmid acquisition have been shown to play a critical role in both short- and long-term plasmid prevalence, particularly in microbiomes with high plasmid/strain diversity.

MOLECULAR SYSTEMS BIOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation

James P. J. Hall et al.

Summary: Plasmids play a crucial role in bacterial genome evolution by transferring genes between lineages, and their fitness costs can be alleviated by single compensatory mutations, which may not act as a long-term barrier to horizontal gene transfer (HGT).

PLOS BIOLOGY (2021)

添加到收藏夹

Review Microbiology

Examining horizontal gene transfer in microbial communities

Iiana Lauren Brito

Summary: The Review discusses the impact of horizontal gene transfer on natural microbial communities and explores the application of new technologies in studying the ecology of HGT, as well as deepening our understanding of gene transfer.

NATURE REVIEWS MICROBIOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities

Aida Alonso-del Valle et al.

Summary: This study reveals that the fitness effects of plasmid pOXA-48_K8 on wild-type bacterial hosts are largely unknown, showing a varying impact across different bacterial isolates. Genomic results also suggest a link between plasmid fitness effects and bacterial phylogeny. Furthermore, incorporating fitness results into a population dynamics model provides new insights into conditions for plasmid stability in bacterial communities.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Review Microbiology

Quantitative analysis of horizontal gene transfer in complex systems

Jenifer Moralez et al.

Summary: Horizontal gene transfer plays a significant role in rapidly spreading diverse traits within bacterial populations, accelerating natural evolution and leading to complex community structures. The critical gene transfer rates underlying these occurrences are highly specific to HGT mechanisms and environmental contexts, historically posing challenges in reliable quantification. Leveraging rigorous quantitative methods to measure these rates has provided fundamental biological insights across multiple scales of complexity.

CURRENT OPINION IN MICROBIOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Increased copy number couples the evolution of plasmid horizontal transmission and plasmid-encoded antibiotic resistance

Tatiana Dimitriu et al.

Summary: Conjugative plasmids can rapidly evolve increased transfer rates and antimicrobial resistance when confronted with susceptible hosts. This evolution is driven by mutations in the copA gene, leading to higher copy numbers and subsequently higher transfer rates and AMR. Correlated selection between plasmid transfer and AMR may increase the spread of AMR within populations and communities.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli

Jonathan H. Bethke et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Exploring the trade-offs between electric heating policy and carbon mitigation in China

Jianxiao Wang et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Ecology

Integrative analysis of fitness and metabolic effects of plasmids in Pseudomonas aeruginosa PAO1

Alvaro San Millan et al.

ISME JOURNAL (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

Evolution of Plasmid-Mediated Antibiotic Resistance in the Clinical Context

Alvaro San Millan

TRENDS IN MICROBIOLOGY (2018)

添加到收藏夹

Article Genetics & Heredity

Ordering the mob: Insights into replicon and MOB typing schemes from analysis of a curated dataset of publicly available plasmids

Alex Orlek et al.

PLASMID (2017)

添加到收藏夹

Article Genetics & Heredity

The evolution of plasmid stability: Are infectious transmission and compensatory evolution competing evolutionary trajectories?

James P. J. Hall et al.

PLASMID (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Persistence and reversal of plasmid-mediated antibiotic resistance

Allison J. Lopatkin et al.

NATURE COMMUNICATIONS (2017)

添加到收藏夹

Article Ecology

Compensatory mutations improve general permissiveness to antibiotic resistance plasmids

Wesley Loftie-Eaton et al.

NATURE ECOLOGY & EVOLUTION (2017)

添加到收藏夹

Article Microbiology

Fitness Costs of Plasmids: a Limit to Plasmid Transmission

Alvaro San Millan et al.

MICROBIOLOGY SPECTRUM (2017)

添加到收藏夹

Article Evolutionary Biology

Multi-host environments select for hostgeneralist conjugative plasmids

Anastasia Kottara et al.

BMC EVOLUTIONARY BIOLOGY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Survival and Evolution of a Large Multidrug Resistance Plasmid in New Clinical Bacterial Hosts

Andreas Porse et al.

MOLECULAR BIOLOGY AND EVOLUTION (2016)

添加到收藏夹

Article Microbiology

Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131

Nicole Stoesser et al.

MBIO (2016)

添加到收藏夹

Article Microbiology

Antibiotics as a selective driver for conjugation dynamics

Allison J. Lopatkin et al.

NATURE MICROBIOLOGY (2016)

添加到收藏夹

Article Evolutionary Biology

The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach

Tom Vogwill et al.

EVOLUTIONARY APPLICATIONS (2015)

添加到收藏夹

Article Biochemical Research Methods

Prokka: rapid prokaryotic genome annotation

Torsten Seemann

BIOINFORMATICS (2014)

添加到收藏夹

Review Microbiology

Escherichia coli ST131, an Intriguing Clonal Group

Marie-Helene Nicolas-Chanoine et al.

CLINICAL MICROBIOLOGY REVIEWS (2014)

添加到收藏夹

Article Chemistry, Physical

Synthesis and patterning of tunable multiscale materials with engineered cells

Allen Y. Chen et al.

NATURE MATERIALS (2014)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

添加到收藏夹

Article Microbiology

The Comprehensive Antibiotic Resistance Database

Andrew G. McArthur et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)

添加到收藏夹

Article Infectious Diseases

Identification of acquired antimicrobial resistance genes

Ea Zankari et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2012)

添加到收藏夹

Review Microbiology

Persistence of antibiotic resistance in bacterial populations

Dan I. Andersson et al.

FEMS MICROBIOLOGY REVIEWS (2011)

添加到收藏夹

Review Microbiology

Regulation of bacterial conjugation: balancing opportunity with adversity

Laura S. Frost et al.

FUTURE MICROBIOLOGY (2010)

添加到收藏夹

Review Microbiology

Mobility of Plasmids

Chris Smillie et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2010)

添加到收藏夹

Review Microbiology

Conjugative DNA metabolism in Gram-negative bacteria

Fernando de la Cruz et al.

FEMS MICROBIOLOGY REVIEWS (2010)

添加到收藏夹

Article Genetics & Heredity

Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths

Marie Touchon et al.

PLOS GENETICS (2009)

添加到收藏夹

Article Biotechnology & Applied Microbiology

The RAST server: Rapid annotations using subsystems technology

Ramy K. Aziz et al.

BMC GENOMICS (2008)

添加到收藏夹

Vertical and horizontal gene transfer tradeoffs direct plasmid fitness

相关参考文献

导出引文

分享论文