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Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension
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Dynamic and Permissive Roles of TRPV1 and TRPV4 Channels for Thermosensation in Mouse Supraoptic Magnocellular Neurosecretory Neurons
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JOURNAL OF NEUROSCIENCE (2013)
TRPV4 partially participates in proliferation of human brain capillary endothelial cells
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TRPV4 channels stimulate Ca2+-induced Ca2+ release in astrocytic endfeet and amplify neurovascular coupling responses
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Activation of Transient Receptor Potential Vanilloid 4 Increases NMDA-Activated Current in Hippocampal Pyramidal Neurons
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FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Emerging role of TRP channels in cell migration: from tumor vascularization to metastasis
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FRONTIERS IN PHYSIOLOGY (2013)
A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors
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EXPERIMENTAL NEUROLOGY (2012)
Stimulation of transient receptor potential vanilloid 4 channel suppresses abnormal activation of microglia induced by lipopolysaccharide
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Region-specific changes in the immunoreactivity of TRPV4 expression in the central nervous system of SOD1G93A transgenic mice as an in vivo model of amyotrophic lateral sclerosis
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JOURNAL OF MOLECULAR HISTOLOGY (2012)
TRPV4 mutations in children with congenital distal spinal muscular atrophy
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TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling
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Elementary Ca2+ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function
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An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure
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SCIENCE TRANSLATIONAL MEDICINE (2012)
Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells
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CELL CALCIUM (2011)
An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Involvement of TRPV4-NO-cGMP-PKG pathways in the development of thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats
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BEHAVIOURAL BRAIN RESEARCH (2010)
Atomic Force Microscopy Reveals the Alternating Subunit Arrangement of the TRPP2-TRPV4 Heterotetramer
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BIOPHYSICAL JOURNAL (2010)
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EMBO MOLECULAR MEDICINE (2010)
A 3.5-nm Structure of Rat TRPV4 Cation Channel Revealed by Zernike Phase-contrast Cryoelectron Microscopy
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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C
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NATURE GENETICS (2010)
Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4
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NATURE GENETICS (2010)
Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C
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NATURE GENETICS (2010)
Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Altered central TRPV4 expression and lipid raft association related to inappropriate vasopressin secretion in cirrhotic rats
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AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation
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EUROPEAN JOURNAL OF CELL BIOLOGY (2009)
Transient Receptor Potential Vanilloid Type 4-Deficient Mice Exhibit Impaired Endothelium-Dependent Relaxation Induced by Acetylcholine In Vitro and In Vivo
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Tyrosine Phosphorylation Modulates the Activity of TRPV4 in Response to Defined Stimuli
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
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JOURNAL OF PSYCHOPHARMACOLOGY (2009)
Modulation of transient receptor potential vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C
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MOLECULAR PAIN (2009)
A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia
Wei Tian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Astrocytes and the regulation of cerebral blood flow
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TRENDS IN NEUROSCIENCES (2009)
Molecular Mechanisms of TRPV4-Mediated Neural Signaling
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CURRENT BIOLOGY (2008)
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3
Dieter D'hoedt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Expression and functional characterization of transient receptor potential vanilloid-related channel 4 (trpv4) in rat cortical astrocytes
V. Benfenati et al.
NEUROSCIENCE (2007)
Effects of body temperature on neural activity in the hippocampus: Regulation of resting membrane potentials by transient receptor potential vanilloid 4
Koji Shibasaki et al.
JOURNAL OF NEUROSCIENCE (2007)
The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels
Tomasz Wegierski et al.
EMBO JOURNAL (2006)
TRPV4-mediated regulation of epithelial permeability
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FASEB JOURNAL (2006)
PACSINs bind to the TRPV4 cation channel - PACSIN 3 modulates the subcellular localization of TRPV4
Math P. Cuajungco et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation
Ralf Koehler et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains
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BMC GENOMICS (2006)
Glycosylation of the osmoresponsive transient receptor potential channel TRPV4 on Asn-651 influences membrane trafficking
HS Xu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices
J Lipski et al.
BRAIN RESEARCH (2006)
Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking
M Arniges et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The mechanosensitive nature of TRPV channels
RG O'Neil et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2005)
Altered thermal selection behavior in mice lacking transient receptor potential vanilloid 4
HS Lee et al.
JOURNAL OF NEUROSCIENCE (2005)
TRPV4 calcium entry channel: a paradigm for gating diversity
B Nilius et al.
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Warm temperature-sensitive transient receptor potential vanilloid 4 (TRPV4) plays an essential role in thermal hyperalgesia
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Molecular determinants in TRPV5 channel assembly
Q Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The neurobiology of glia in the context of water and ion homeostasis
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Microfilament-associated protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4)
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Abnormal osmotic regulation in trpv4-/- mice
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Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site
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Impaired osmotic sensation in mice lacking TRPV4
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Modulation of TRPV4 gating by intra- and extracellular Ca2+
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