☆ 4.7 Article

Advancements in nanoparticle-based treatment approaches for skin cancer therapy

Molecular Cancer (2023)

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Sahar Tahaghoghi-Hajghorbani et al.

Summary: A new liposomal EPA formulation was developed in this study to reduce dose, side effects, and treatment costs. The use of nanoliposomal EPA showed more efficacy than free EPA in inhibiting tumor growth in a melanoma model, suggesting its potential for further clinical studies in immunotherapy.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Article Polymer Science

An insight into aptamer engineered dendrimer for cancer therapy

Afsana Sheikh et al.

Summary: Aptamers are crucial in drug delivery but prone to degradation by endonucleases; bioconjugation with dendrimers offers a novel platform for improved targeted drug delivery system.

EUROPEAN POLYMER JOURNAL (2021)

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Article Chemistry, Multidisciplinary

Trojan Horse Salmonella Enabling Tumor Homing of Silver Nanoparticles via Neutrophil Infiltration for Synergistic Tumor Therapy and Enhanced Biosafety

Ze Mi et al.

Summary: Researchers enhanced the efficacy and biosafety of Salmonella by using silver nanoparticles, enabling tumor-targeting AgNPs to exert multiple functions in the tumor and ultimately eliminate the tumor with high biosafety.

NANO LETTERS (2021)

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Review Biotechnology & Applied Microbiology

Engineering precision nanoparticles for drug delivery

Michael J. Mitchell et al.

Summary: The development of nanoparticles has shown promising clinical applications, overcoming the limitations of therapeutic interventions and biological barriers. Precision therapies have enhanced treatment efficacy through personalized interventions. Advancements in nanoparticle design aim to optimize drug delivery, improving efficacy in general applications and enabling tailored designs for precision applications.

NATURE REVIEWS DRUG DISCOVERY (2021)

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Article Biochemistry & Molecular Biology

Poly(amidoamine) Dendrimers as Nanocarriers for 5-Fluorouracil: Effectiveness of Complex Formation and Cytotoxicity Studies

Magdalena Szota et al.

Summary: Two generations of PAMAM dendrimers were studied as potential carriers for the anticancer drug 5-fluorouracil, with results showing that the protonation degree of starting components is crucial for complex formation. The system was able to attach a number of 5FU molecules per dendrimer molecule, and cytotoxicity tests demonstrated a significant decrease in cell viability for malignant cell lines when exposed to PAMAM-5FU complexes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Biochemistry & Molecular Biology

Verteporfin-Loaded Mesoporous Silica Nanoparticles' Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo

Nausicaa Clemente et al.

Summary: The combination of mesoporous silica nanoparticles (MSN) conjugated with verteporfin (Ver-MSNs) in photodynamic therapy (PDT) for melanoma treatment showed significant anti-metastasis and anti-angiogenesis effects in a mouse model.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Chemistry, Multidisciplinary

RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy

Afsana Sheikh et al.

Summary: A bird's eye view is needed in cancer research to address the shortcomings of chemotherapy, with targeted therapy showing promise in providing more efficient treatment for tumor cells.

JOURNAL OF CONTROLLED RELEASE (2021)

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Review Biochemistry & Molecular Biology

Current Limitations and Recent Progress in Nanomedicine for Clinically Available Photodynamic Therapy

Jooho Park et al.

Summary: Photodynamic therapy (PDT) using oxygen, light, and photosensitizers is a promising approach for cancer treatment. Current progress involves enhancing accumulation of photosensitizers in tumor sites using nanocarriers and future research directions include improving drug localization and optimizing treatment outcomes.

BIOMEDICINES (2021)

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Article Chemistry, Multidisciplinary

Robust Nanovaccine Based on Polydopamine-Coated Mesoporous Silica Nanoparticles for Effective Photothermal-Immunotherapy Against Melanoma

Chenlu Huang et al.

Summary: The nanoparticle-based combination therapy of photothermal therapy (PTT) and immunotherapy shows promising potential for cancer treatment by ablating tumors and eliciting host immune responses.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Review Medicine, Research & Experimental

The role of the Golgi apparatus in disease (Review)

Jianyang Liu et al.

Summary: The Golgi apparatus plays a crucial role in cellular homeostasis and is linked to various diseases. Mutations in genes encoding Golgi resident proteins can lead to diseases, typically involving defects in membrane trafficking, protein mislocalization, and impaired glycosylation. Detection of Golgi resident proteins in human serum samples may serve as a diagnostic tool, while the central role of Golgi apparatus in membrane trafficking pathways presents potential targets for disease therapy.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021)

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Article Nanoscience & Nanotechnology

Cancer Cell Membrane Camouflaged Mesoporous Silica Nanoparticles Combined with Immune Checkpoint Blockade for Regulating Tumor Microenvironment and Enhancing Antitumor Therapy

Peiqi Zhao et al.

Summary: The study introduces a biocompatible and tumor acidic environment responsive CCM-camouflaged mesoporous silica nanoparticle (CMSN) loaded with dacarbazine (DTIC) and combined with aPD1 for improved antitumor efficacy.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Article Biotechnology & Applied Microbiology

Development of S75:R25 bupivacaine-loaded lipid nanoparticles functionalized with essential oils for treating melanoma

Gabriela Geronimo et al.

Summary: This study developed two NLC formulations using lavender or melaleuca oils, which showed stable release properties and significant cytotoxic effects on mice and human melanoma cells.

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY (2021)

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Article Pharmacology & Pharmacy

Anti-skin cancer activity of Alpinia calcarata ZnO nanoparticles: Characterization and potential antimicrobial effects

Mohanapriya Chelladurai et al.

Summary: The skin, being the most exposed human organ to pollution, is susceptible to various hazards leading to infections and skin cancer. Nanotechnology, especially green-synthesized nanoparticles combined with Alpinia calcarata rhizomes, show promise as an alternative for skin treatments. Zinc oxide nanoparticles derived from Alpinia calcarata extract exhibit biocidal properties against microorganisms and potential for treating skin ailments.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2021)

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Article Multidisciplinary Sciences

Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression

Kerstin Johann et al.

Summary: The release of an adenylate cyclase inhibitor from micelles can restore antitumor immunity in melanoma, and when combined with regulatory T cell depletion, it can lead to remission of the tumor.

NATURE COMMUNICATIONS (2021)

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Article Chemistry, Medicinal

D-α-Tocopherol-Based Micelles for Successful Encapsulation of Retinoic Acid

Guendalina Zuccari et al.

Summary: The study showed that ATRA-TPGS exhibited small sizes, low polydispersity, slightly negative zeta potential, and proved good encapsulation efficiency. ATRA-TPGSs also demonstrated enhanced cytotoxic effects on melanoma cells, indicating a potential alternative for improving patient compliance and achieving more efficacious therapeutic outcomes.

PHARMACEUTICALS (2021)

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Review Dermatology

Mohs micrographic surgery: a review of indications, technique, outcomes, and considerations

Guilherme Canho Bittner et al.

Summary: Mohs micrographic surgery is a specialized form of skin cancer surgery with the highest cure rates for several cutaneous malignancies. It involves the dermatologist acting as both surgeon and pathologist, sparing normal tissue and managing complications. This procedure is considered the standard of care for high-risk skin cancers and is increasingly used for other rare tumors with superior cure rates.

ANAIS BRASILEIROS DE DERMATOLOGIA (2021)

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Article Pharmacology & Pharmacy

High anticancer efficacy of solid lipid nanoparticles containing Zataria multiflora essential oil against breast cancer and melanoma cell lines

Alireza Valizadeh et al.

Summary: The study found that solid-lipid nanoparticles containing essential oil of Zataria multiflora showed a distinct antiproliferative efficacy against breast cancer and melanoma cells, making it a potential green candidate for anticancer treatment in further in vitro and in vivo studies.

BMC PHARMACOLOGY & TOXICOLOGY (2021)

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Article Nanoscience & Nanotechnology

Dual Modal Imaging-Guided Drug Delivery System for Combined Chemo-Photothermal Melanoma Therapy

Dong Zhang et al.

Summary: A multifunctional drug delivery system was developed for melanoma treatment by incorporating drugs into manganese-doped mesoporous silica nanoparticles, coupled with MRI and photothermal imaging. The system showed excellent drug loading and release efficiency, imaging capability, photothermal heating ability, and demonstrated superior antitumor effect in both in vitro and in vivo experiments, highlighting its potential for melanoma therapy.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Article Pharmacology & Pharmacy

Docetaxel and Lidocaine Co-Loaded (NLC-in-Hydrogel) Hybrid System Designed for the Treatment of Melanoma

Ludmilla David de Moura et al.

Summary: This study developed a novel drug formulation for the treatment of melanoma using nanotechnology, which showed potential therapeutic effects on melanoma without significant adverse reactions.

PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Microneedles for gene and drug delivery in skin cancer therapy

Defu Zhi et al.

Summary: Microneedles are an effective delivery method for skin cancer treatment, providing advantages such as bypassing the stratum corneum barrier, delivering drugs and genes in a simple, safe, and painless manner, and improving therapeutic effects. The combination of microneedles with other treatment strategies like photothermal therapy shows promise in enhancing the overall treatment outcomes for skin cancer.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Biochemistry & Molecular Biology

Antitumor potential of cisplatin loaded into SBA-15 mesoporous silica nanoparticles against B16F1 melanoma cells: in vitro and in vivo studies

Dijana Draca et al.

Summary: The study demonstrates that mesoporous silica SBA-15 loaded with cisplatin exhibits high cytotoxicity against low metastatic mouse melanoma cells. The main mode of cell death is through apoptosis and nitric oxide production, suggesting potential therapeutic effects on melanoma.

JOURNAL OF INORGANIC BIOCHEMISTRY (2021)

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Article Chemistry, Multidisciplinary

BSA/Silver Nanoparticle-Loaded Hydrogel Film for Local Photothermal Treatment of Skin Cancer

Reeju Amatya et al.

Summary: The study developed a hydrogel film containing BSA/AgNPs with excellent photothermal activity for effective and safe topical photothermal treatment of skin cancer. The results showed significant inhibition of tumor growth with no apparent toxicity in mice, demonstrating the potential of BSA/AgNP-loaded hydrogel films as a promising treatment for skin cancer.

PHARMACEUTICAL RESEARCH (2021)

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Article Chemistry, Multidisciplinary

Novel Curcumin-Resveratrol Solid Nanoparticles Synergistically Inhibit Proliferation of Melanoma Cells

Gayathri Heenatigala Palliyage et al.

Summary: Polyphenols such as curcumin and resveratrol have shown potential to inhibit proliferation of aggressive melanoma cells. A topical delivery system using solid lipid nanoparticles (SLNs) loaded with these polyphenols was found to enhance skin penetration and anti-cancer efficacy in this study.

PHARMACEUTICAL RESEARCH (2021)

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Article Chemistry, Physical

Encapsulation and Enhanced Release of Resveratrol from Mesoporous Silica Nanoparticles for Melanoma Therapy

Diogo Marinheiro et al.

Summary: The study evaluated the potential of RES-loaded mesoporous silica nanoparticles for melanoma treatment, demonstrating their potential in promoting RES release. In vitro experiments showed that RES-loaded nanoparticles exhibited cytotoxicity against melanotic cell lines, with a stronger effect on amelanotic cells.

MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Silver Nanoparticles from Annona muricata Peel and Leaf Extracts as a Potential Potent, Biocompatible and Low Cost Antitumor Tool

Maria G. Gonzalez-Pedroza et al.

Summary: In this study, silver nanoparticles were successfully synthesized using extracts from Annona muricata, showing a more potent anti-tumor effect in fruit peel extract compared to leaf extract. The nanoparticles demonstrated significant cancer cell destruction capabilities at low concentrations, making them a promising and cost-effective tool for cancer treatment.

NANOMATERIALS (2021)

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Review Chemistry, Multidisciplinary

Silver Nanoparticles as Carriers of Anticancer Drugs for Efficient Target Treatment of Cancer Cells

Helena I. O. Gomes et al.

Summary: Nanotechnology has rapidly evolved over the last decade and has found applications in various fields, with nanoparticles being explored as drug carriers with controlled and targeted release advantages. Silver nanoparticles, with unique properties, are increasingly being studied for drug transport, particularly in cancer treatment where conventional chemotherapy has limitations in bioavailability and adverse effects. Strategies utilizing silver nanoparticles as anticancer drug carriers show promise in overcoming these challenges.

NANOMATERIALS (2021)

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Review Chemistry, Multidisciplinary

Lipid Nanoparticles as Carriers for Bioactive Delivery

Neerupma Dhiman et al.

Summary: Nanotechnology has significantly impacted industries like pharmaceuticals, biotechnology, food, and cosmetics, especially in improving the solubility and bioavailability of lipophilic drugs. Various nanotechnology-based drug delivery systems, such as solid lipid nanoparticulate drug delivery systems and emulsion-based nanodrug delivery systems, play crucial roles in the targeted delivery of poorly soluble drugs. This review provides a comprehensive overview of lipid nanoparticles as carriers of bioactive molecules, covering aspects like synthesis, characterization, advantages, disadvantages, toxicity, and applications in the medical field. Recent developments in patents and clinical trials related to solid lipid nanoparticles (SLNs) and nanostructure lipid carriers (NLCs) are also discussed.

FRONTIERS IN CHEMISTRY (2021)

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Article Pharmacology & Pharmacy

pH-Responsive Release of Ruthenium Metallotherapeutics from Mesoporous Silica-Based Nanocarriers

Minja Mladenovic et al.

Summary: Ruthenium complexes with potent cytotoxic activity are being studied for cancer treatment, with a focus on constructing drug delivery systems using mesoporous silica nanoparticles functionalized with pH-responsive ligands to enhance the release of Ru(II) complexes in tumor acidic environments. In vitro evaluations on metastatic melanoma cells demonstrate the promising pH-responsive delivery of metallotherapeutics and targeted treatment of cancer using these designed MSN nanocarriers.

PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

BSA-Silver Nanoparticles: A Potential Multimodal Therapeutics for Conventional and Photothermal Treatment of Skin Cancer

Dasom Kim et al.

Summary: Silver nanoparticles coated with BSA were developed and studied for their potential in cancer therapy, showing cytotoxic effects on melanoma cells, anti-angiogenic effects on endothelial cells, and photothermal conversion ability, suggesting their promise for skin cancer treatment.

PHARMACEUTICS (2021)

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Article Biochemistry & Molecular Biology

Proof-of-Concept Study of Multifunctional Hybrid Nanoparticle System Combined with NIR Laser Irradiation for the Treatment of Melanoma

Joana Lopes et al.

Summary: The study proposes a multifunctional nanoparticle-based therapy for superficial melanoma, which has shown significant efficacy in both in vitro and in vivo experiments, while demonstrating a high level of safety.

BIOMOLECULES (2021)

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Review Biochemistry & Molecular Biology

Advances in Nanomaterial-Mediated Photothermal Cancer Therapies: Toward Clinical Applications

Hwa Seung Han et al.

Summary: Photothermal therapy (PTT) is a promising noninvasive cancer treatment strategy, although current limitations include low photothermal conversion efficiency, low accumulation of agents in tumor tissue, and heat resistance in specific cancer types. Innovative nanomaterial-based approaches show potential for improving therapeutic outcomes and reducing side effects in PTT applications.

BIOMEDICINES (2021)

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Review Dermatology

Melanoma pathology: new approaches and classification

I. Yeh et al.

Summary: Cancer is caused by pathogenic alterations of the genome and epigenome, and melanoma is a complex disease that can be classified based on the cell of origin, etiology, clinical appearance, and treatment response. This article reviews the classification of melanoma and the use of molecular diagnostics for its diagnosis in the context of histopathological assessment.

BRITISH JOURNAL OF DERMATOLOGY (2021)

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Article Oncology

Resveratrol for cancer therapy: Challenges and future perspectives

Boxu Ren et al.

Summary: Despite its potential anticancer effects, resveratrol faces obstacles in clinical translation due to poor pharmacokinetics, low potency, and nephrotoxicity in certain patients. New strategies to enhance its bioavailability and develop more potent analogues are proposed to overcome these challenges and advance resveratrol in cancer therapy.

CANCER LETTERS (2021)

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Article Biophysics

PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy

Bhavya Surekha et al.

Summary: PAMAM dendrimers are novel polymeric structures with defined nano-size and multiple active functional groups, ideal for cancer therapy. Their modifiable surface functionalities and high drug encapsulation rate make them widely used in drug delivery and gene therapy.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

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Review Chemistry, Inorganic & Nuclear

Emerging role of nanoclays in cancer research, diagnosis, and therapy

Diana Peixoto et al.

Summary: Nanoclays with tunable properties, such as physicochemical, morphological, and structural, show potential as multifunctional biocompatible nanocarriers for versatile applications in cancer research, diagnosis, and therapy.

COORDINATION CHEMISTRY REVIEWS (2021)

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Article Pharmacology & Pharmacy

Combinatorial lipid-nanosystem for dermal delivery of 5-fluorouracil and resveratrol against skin cancer: Delineation of improved dermatokinetics and epidermal drug deposition enhancement analysis

Mohammad Kashif Iqubal et al.

Summary: A combinatorial nanostructured lipid carrier gel of 5-fluorouracil and resveratrol was formulated, optimized, and characterized in this study, showing potential for enhanced permeation and synergistic effects against skin cancer. Stability studies and in vitro release studies demonstrated improved drug release and penetration capabilities of the optimized lipid-nanosystem.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2021)

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Article Polymer Science

Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery

Vanshikha Singh et al.

Summary: Dendrimers are versatile nanocarriers capable of delivering drugs, antibodies, or therapeutic genes, with potential benefits in cancer therapy. Particularly, PPI dendrimers can be customized for targeted drug delivery to specific tumor sites, enhancing efficacy and reducing adverse effects.

EUROPEAN POLYMER JOURNAL (2021)

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Article Oncology

Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2

Wei Huang et al.

Summary: Sorafenib is a multi-kinase inhibitor known for its tumor suppressor properties, but its clinical application is limited by side effects. This study aimed to investigate the anti-tumor effects of new sorafenib derivatives-capped gold nanoparticles. The results showed that AuNPs could deliver new sorafenib derivatives into tumor tissues, suppressing tumor migration, EMT, and angiogenesis.

EXPERIMENTAL CELL RESEARCH (2021)

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Article Biochemistry & Molecular Biology

Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas

Jenifer P. Goncalves et al.

Summary: Researchers investigated the efficacy and safety of gum arabic-functionalized gold nanorods (GA-AuNRs) against triple wild-type melanoma, finding that GA-AuNRs significantly reduced primary tumor growth and induced histological features associated with better prognosis, while also lowering the depth of superficial lung metastasis and the incidence of intrapulmonary metastasis.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Review Biochemistry & Molecular Biology

Basic Methods for Preparation of Liposomes and Studying Their Interactions with Different Compounds, with the Emphasis on Polyphenols

Luka Sturm et al.

Summary: Studying the interactions between lipid membranes and bioactive molecules is crucial for understanding their effects on lipid bilayers, which can be utilized for inhibiting bacteria, cancer cells, eliminating viruses, or maintaining healthy cells. Liposomes, as model lipid membranes, provide a basic and stable platform for investigating the effects of bioactive compounds on lipid membranes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Nanoscience & Nanotechnology

Green Synthesized Honokiol Transfersomes Relieve the Immunosuppressive and Stem-Like Cell Characteristics of the Aggressive B16F10 Melanoma

Yasmeen Ezzeldeen et al.

Summary: This study aimed to fabricate HK transfersomes for topical treatment of melanoma, which showed potential to alleviate the immunosuppressive characteristics of the tumor and reduce the expression of stem-like cell markers. The optimized formula exhibited a mean size of 190 nm and highly negative surface charge, with promising results both in vitro and in combination with other drugs.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Article Pharmacology & Pharmacy

Paclitaxel anticancer activity is enhanced by the MEK 1/2 inhibitor PD98059 in vitro and by PD98059-loaded nanoparticles in BRAFV600E melanoma-bearing mice

Aml Mekkawy et al.

Summary: The study explores the efficacy of a combination therapy of PTX and PD98059 in enhancing cytotoxicity against melanoma cells expressing the BRAF mutation. The use of PD98059-loaded NPs showed superior cellular uptake and cytotoxicity compared to soluble PD98059, suggesting a potential therapeutic approach for improving survival outcomes in patients with metastatic melanoma.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Advanced nanomedicine approaches applied for treatment of skin carcinoma

Harsimran Kaur et al.

Summary: Skin cancer is a common malignancy affecting a large population, with treatment strategies focusing on surgery, radiation, and chemotherapy. Nanoscaled materials are recognized as potential carriers for selective response to cancerous cells.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Medicine, Research & Experimental

Improving Dermal Delivery of Rose Bengal by Deformable Lipid Nanovesicles for Topical Treatment of Melanoma

Sara Demartis et al.

Summary: Cutaneous melanoma is an aggressive form of skin cancer with limited therapeutic options leading to increased mortality rates. This study proposes the use of deformable lipid nanovesicles for targeted dermal delivery of Rose Bengal to melanoma lesions, effectively eradicating them without the need for external stimuli. These transfersomes not only improve the penetration of RB into deeper skin layers but also protect it from degradation, showing potential as an alternative tool for fighting against primary melanoma lesions.

MOLECULAR PHARMACEUTICS (2021)

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Article Medicine, Research & Experimental

Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides

Bas M. Bavelaar et al.

Summary: In this study, gold nanoparticles (AuNPs) were used to enhance cellular uptake of oligonucleotides targeting telomerase. The addition of Tat to AuNPs increased nuclear localization and induced DNA double-strand breaks in telomerase-positive cells. In-111-Match-AuNP-Tat shows promise as a vector for delivering radionuclides to cancer cells while sensitizing them to the effects of emitted radiation.

MOLECULAR PHARMACEUTICS (2021)

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Review Chemistry, Multidisciplinary

Ethosomes as Nanocarriers for the Development of Skin Delivery Formulations

Ana Claudia Paiva-Santos et al.

Summary: The use of nanotechnology in developing efficient drug delivery systems, such as ethosomes, which contain a high concentration of ethanol, has unique advantages in enhancing drug permeation across the skin. Ethosomes show promise as an alternative to traditional liposomes for delivering therapeutic agents for various skin pathologies, with potential applications in acne, psoriasis, alopecia, skin infections, hormonal deficiencies, among others. Further research is needed to fully explore the potential of ethosomal-based formulations in skin delivery of active ingredients.

PHARMACEUTICAL RESEARCH (2021)

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Review Pharmacology & Pharmacy

Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies

Mohammed Elmowafy et al.

Summary: NLCs, with exceptional physicochemical and biocompatible characteristics, have shown great potential for innovative therapeutic applications through various administration routes and can be fabricated by different techniques. Studies have demonstrated the promise of NLCs in future innovations in therapeutic applications.

SAUDI PHARMACEUTICAL JOURNAL (2021)

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Review Oncology

Photodynamic Therapy: A Compendium of Latest Reviews

Jose Francisco Algorri et al.

Summary: In recent years, numerous reviews about photodynamic therapy and related topics have been published, covering a wide range of complex subjects. This work aims to summarize the latest reviews in the field and provide researchers with key issues and main conclusions for further study. The exponential growth of scientific publications in photodynamic therapy over the last two decades has led to the compilation of a compendium of reviews, classified under different topics, which may be of interest to a broad audience.

CANCERS (2021)

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Review Oncology

Recent Advances in Zinc Oxide Nanoparticles (ZnO NPs) for Cancer Diagnosis, Target Drug Delivery, and Treatment

Sumaira Anjum et al.

Summary: Despite advancements in medicine, cancer remains a deadly and somber disease caused by uncontrolled cell proliferation. Traditional medications and chemotherapies have limitations such as reduced bioavailability and significant side effects. Nanotechnology has rapidly evolved and offers potential in healthcare, with nanoscale materials showing promise in cancer treatment due to their low risk. Zinc oxide nanoparticles have demonstrated their potential in diagnosing and treating various cancers due to their biocompatibility and unique properties. Their ability to induce reactive oxygen species in cancer cells, leading to apoptosis, makes them effective in targeted drug delivery.

CANCERS (2021)

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Article Pharmacology & Pharmacy

Improvement of Imiquimod Solubilization and Skin Retention via TPGS Micelles: Exploiting the Co-Solubilizing Effect of Oleic Acid

Martina Ghezzi et al.

Summary: The study aimed to improve the solubility and skin retention of Imiquimod using micelles of TPGS and oleic acid, which showed significant enhancement in drug solubility and micellar stability. The delivery efficiency of this formulation was found to be 42- and 25-folds higher than that of commercial creams after application.

PHARMACEUTICS (2021)

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Article Pharmacology & Pharmacy

Hyaluronic Acid Coating Reduces the Leakage of Melittin Encapsulated in Liposomes and Increases Targeted Delivery to Melanoma Cells

Yanyan Li et al.

Summary: The study successfully reduced the toxicity and increased the anti-tumor effects of melittin by designing melittin liposomes and HA-modified melittin liposomes.

PHARMACEUTICS (2021)

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Review Oncology

Recent progress of graphene oxide-based multifunctional nanomaterials for cancer treatment

Lijun Liu et al.

Summary: Graphene oxide-based multifunctional nanomaterials have shown great potential in cancer treatment, serving as ideal carriers for drugs/genes, phototherapy, and bioimaging. Their excellent biocompatibility and large surface area make them a promising candidate for various biomedical applications.

CANCER NANOTECHNOLOGY (2021)

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Review Health Care Sciences & Services

The Enhanced Permeability and Retention (EPR) Effect: The Significance of the Concept and Methods to Enhance Its Application

Jun Wu

Summary: Chemotherapy for human solid tumors faces challenges in delivering anticancer compounds selectively into tumor tissues to maintain effective concentration levels for a certain duration, hindering the execution of anticancer activities. Targeting therapy via the enhanced permeability and retention effect may not always be successful, as it depends on tumor type, location, blood perfusion status, and properties of macromolecular anticancer agents. Efforts to maximize the EPR effect in developing smarter nanomedicines are essential for successful clinical applications.

JOURNAL OF PERSONALIZED MEDICINE (2021)

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Article Chemistry, Applied

Statistical optimization of novel acemannan polysaccharides assisted TiO2 nanorods based nanofibers for skin cancer application

Rajalakshmi Ekambaram et al.

Summary: This study reported the fabrication of novel nanofiber materials using green synthesis for combating skin cancer cells, with good antibacterial and antioxidant properties demonstrated through comprehensive characterizations. The nano-composite fibrous scaffold showed promise as an effective transdermal patch for melanoma applications.

CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS (2021)

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Article Multidisciplinary Sciences

Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties

Yan Cao et al.

Summary: This study reported a simple and green method to prepare bimetallic nanoparticles using Sambucus nigra L. extract, involving zinc oxide and copper oxide. The nanoparticles were found to contain polygonal ZnO NPs with hexagonal phase and spherical CuO NPs with monoclinic phase. The bimetallic ZnO/CuO NPs showed high toxicity on melanoma cancer cells while their toxicity on lung cancer cells was low.

SCIENTIFIC REPORTS (2021)

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Article Nanoscience & Nanotechnology

Antibody-Conjugated Gel-Coated Single-Walled Carbon Nanotubes as Photothermal Agents

Yukiko Nagai et al.

Summary: The study demonstrates a method of post-modifying thiol-containing antibodies using maleimide chemistry, allowing SWCNTs to maintain their photothermal conversion efficiency even after conjugation with antibodies. This method shows potential for the development of specific antibodies and other targeting agents, with a wide range of applications.

ACS APPLIED BIO MATERIALS (2021)

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Article Biochemistry & Molecular Biology

Quality by Design for Development, Optimization and Characterization of Brucine Ethosomal Gel for Skin Cancer Delivery

Tamer A. Ismail et al.

Summary: The study demonstrated that BRU-loaded ethosomal gel exhibited significant anticancer activity against A375 human melanoma cell lines, providing strong motivation for further investigation of BRU-loaded ethosomal gel as a prospective therapeutic strategy for melanoma treatment.

MOLECULES (2021)

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Article Engineering, Environmental

Characterization and in vitro cytotoxic assessment of zinc oxide nano-particles in human epidermoid carcinoma cells

Mohd Farhan Khan et al.

Summary: The study showed that ZON-2 exhibited more cytotoxic effect than ZON-1 on the A431 cell line. ZON-2 also had a greater impact on ROS generation and cell apoptosis in comparison to ZON-1.

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2021)

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Article Materials Science, Biomaterials

Co-delivery of anionic epitope/CpG vaccine and IDO inhibitor by self-assembled cationic liposomes for combination melanoma immunotherapy

Qi Su et al.

Summary: Cationic polymer-lipid hybrid nanovesicle (P/LNV)-based liposomes have been designed to enhance the immunogenicity of peptide antigens and block immune checkpoint, leading to increased therapeutic efficiency in cancer immunotherapy.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

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Article Materials Science, Biomaterials

Topical delivery of chemotherapeutic drugs using nano-hybrid hydrogels to inhibit post-surgical tumour recurrence†

Chendan Liu et al.

Summary: The study developed a nano-hybrid hydrogel for topical delivery of a chemotherapeutic drug to inhibit post-surgical tumour relapse, demonstrating its efficacy in slowing down tumour relapse. By prolonging drug retention at the administered sites and increasing drug accumulation in cancer cells, a more effective treatment outcome was achieved.

BIOMATERIALS SCIENCE (2021)

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Article Materials Science, Biomaterials

Conductive all-carbon nanotube layers: Results on attractive physicochemical, anti-bacterial, anticancer and biocompatibility properties

Aleksandra Benko et al.

Summary: The study focused on the physicochemical, electrochemical, and biological performance of four types of all-carbon nanotube layers, finding that these materials have inhibitory effects on the proliferation of bacteria and cancer cells, while having no negative effects on mammalian cells and not requiring drug intervention.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

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Article Medicine, Research & Experimental

Tumor microenvironment remodeling and tumor therapy based on M2-like tumor associated macrophage-targeting nano-complexes

Shulan Han et al.

Summary: The research demonstrated that the nano-complexes facilitated the delivery of baicalin, antigen, and immunostimulants to M2-like TAMs, resulting in the reversal of the M2-like TAM phenotype and remodeling of the tumor microenvironment to kill tumor cells.

THERANOSTICS (2021)

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Review Oncology

Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment

Tran Q. Huy et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2020)

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Article Chemistry, Multidisciplinary

Mesoporous Silica Nanoparticles for Drug Delivery

Miguel Manzano et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

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Article Chemistry, Multidisciplinary

Non-covalent glycosylated gold nanoparticles/peptides nanovaccine as potential cancer vaccines

Liming Zeng et al.

CHINESE CHEMICAL LETTERS (2020)

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Article Pathology

Melanoma pathology reporting and staging

Richard A. Scolyer et al.

MODERN PATHOLOGY (2020)

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Article Materials Science, Biomaterials

Targeted and Reduction-Sensitive Cross-Linked PLGA Nanotherapeutics for Safer and Enhanced Chemotherapy of Malignant Melanoma

Xiuxiu Wang et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

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Article Pharmacology & Pharmacy

Effect of a Solid Lipid Nanoparticle Formulation on the Bioavailability of 4-(N)-Docosahexaenoyl 2′, 2′-Difluorodeoxycytidine After Oral Administration

Solange A. Valdes et al.

AAPS PHARMSCITECH (2020)

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Article Nanoscience & Nanotechnology

Gold Nanorods and Nanoprisms Mediate Different Photothermal Cell Death Mechanisms In Vitro and In Vivo

Maria Moros et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Novel Silver-Platinum Nanoparticles for Anticancer and Antimicrobial Applications

Aida Lopez Ruiz et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

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Article Biochemistry & Molecular Biology

Zinc oxide nanoparticles synthesized from Cardiospermum halicacabum and its anticancer activity in human melanoma cells (A375) through the modulation of apoptosis pathway

Xi Duan et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

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Article Biochemistry & Molecular Biology

Combined X-ray radiotherapy and laser photothermal therapy of melanoma cancer cells using dual-sensitization of platinum nanoparticles

F. Daneshvar et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

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Article Materials Science, Biomaterials

Improved delivery of doxorubicin using rationally designed PEGylated platinum nanoparticles for the treatment of melanoma

Sudip Mukherjee et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

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Review Biochemistry & Molecular Biology

Photodynamic Therapy for Cancer: What's Past is Prologue

Michael R. Hamblin

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2020)

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Article Multidisciplinary Sciences

CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction

Elif Aplak et al.

PLOS ONE (2020)

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Article Surgery

Epidemiology and Risk Factors of Melanoma

Stephanie Carr et al.

SURGICAL CLINICS OF NORTH AMERICA (2020)

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Article Acoustics

Effect of targeted gold nanoparticles size on acoustic cavitation: An in vitro study on melanoma cells

Ahmad Shanei et al.

ULTRASONICS (2020)

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Review Materials Science, Multidisciplinary

Mesoporous Silica Nanoparticles for Bio-Applications

Violeta-Carolina Niculescu

FRONTIERS IN MATERIALS (2020)

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Article Biotechnology & Applied Microbiology

Platelet-Like Gold Nanostars for Cancer Therapy: The Ability to Treat Cancer and Evade Immune Reactions

Min Woo Kim et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Review Chemistry, Multidisciplinary

Nanoarchitectured Structure and Surface Biofunctionality of Mesoporous Silica Nanoparticles

Ranjith Kumar Kankala et al.

ADVANCED MATERIALS (2020)

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Review Oncology

The Role of Anti-PD-1/PD-L1 in the Treatment of Skin Cancer

James Randall Patrinely et al.

BIODRUGS (2020)

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Article Engineering, Biomedical

Injectable dual-scale mesoporous silica cancer vaccine enabling efficient delivery of antigen/adjuvant-loaded nanoparticles to dendritic cells recruited in local macroporous scaffold

Thanh Loc Nguyen et al.

BIOMATERIALS (2020)

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Review Pharmacology & Pharmacy

Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice

Amit S. Choudhari et al.

FRONTIERS IN PHARMACOLOGY (2020)

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Review Pharmacology & Pharmacy

Recent advances in theranostic polymeric nanoparticles for cancer treatment: A review

Shikha Indoria et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Development and in-vitro evaluation of co-loaded berberine chloride and evodiamine ethosomes for treatment of melanoma

Hongmei Lin et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Control of basal cell carcinoma via positively charged ethosomes of Vismodegib: In vitro and in vivo studies

Amr F. Gamal et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

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Article Chemistry, Multidisciplinary

Comparative cytotoxic effect of citrate-capped gold nanoparticles with different sizes on noncancerous and cancerous cell lines

Indiani Conti Della Vechia et al.

JOURNAL OF NANOPARTICLE RESEARCH (2020)

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Review Pharmacology & Pharmacy

Nanostructured Lipid Carriers for Delivery of Chemotherapeutics: A Review

Mohamed Haider et al.

PHARMACEUTICS (2020)

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Article Materials Science, Multidisciplinary

Green synthesized ZnO nanosheets from banana peel extract possess anti- bacterial activity and anti-cancer activity

Jittiporn Ruangtong et al.

MATERIALS TODAY COMMUNICATIONS (2020)

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Article Nanoscience & Nanotechnology

Combination of Nucleic Acid and Mesoporous Silica Nanoparticles: Optimization and Therapeutic Performance In Vitro

Ridhima Juneja et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Review Pharmacology & Pharmacy

Nanoparticles for topical drug delivery: Potential for skin cancer treatment

Vinu Krishnan et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Article Chemistry, Multidisciplinary

Preliminary Assays towards Melanoma Cells Using Phototherapy with Gold-Based Nanomaterials

Joana Lopes et al.

NANOMATERIALS (2020)

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Article Nanoscience & Nanotechnology

ICG-Loaded PEGylated BSA-Silver Nanoparticles for Effective Photothermal Cancer Therapy

Taehoon Park et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

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Review Cell Biology

Repositioning Lidocaine as an Anticancer Drug: The Role Beyond Anesthesia

Daipeng Zhou et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

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Review Biotechnology & Applied Microbiology

Multifunctional Gold Nanoparticles: A Novel Nanomaterial for Various Medical Applications and Biological Activities

Xiaopei Hu et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

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Article Chemistry, Multidisciplinary

Transdermal siRNA delivery by pH-switchable micelles with targeting effect suppress skin melanoma progression

Mao-Ze Wang et al.

JOURNAL OF CONTROLLED RELEASE (2020)

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Article Materials Science, Biomaterials

Gold nanoparticle-assisted enhancement in bioactive properties of Australian native plant extracts, Tasmannia lanceolata and Backhousia citriodora

Roshanak Khandanlou et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

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Article Engineering, Biomedical

Photocontrolled miR-148b nanoparticles cause apoptosis, inflammation and regression of Ras induced epidermal squamous cell carcinomas in mice

Yiming Liu et al.

BIOMATERIALS (2020)

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Article Chemistry, Applied

Dextran methacrylate hydrogel microneedles loaded with doxorubicin and trametinib for continuous transdermal administration of melanoma

Shanghui Huang et al.

CARBOHYDRATE POLYMERS (2020)

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Article Pharmacology & Pharmacy

Formulation of Stattic as STAT3 inhibitor in nanostructured lipid carriers (NLCs) enhances efficacy of doxorubicin in melanoma cancer cells

Jamal Mohammadian et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020)

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Article Biophysics

cRGD mediated redox and pH dual responsive poly(amidoamine) dendrimer-poly(ethylene glycol) conjugates for efficiently intracellular antitumor drug delivery

Yifei Wang et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

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Article Biochemistry & Molecular Biology

Anticancer Properties of Platinum Nanoparticles and Retinoic Acid: Combination Therapy for the Treatment of Human Neuroblastoma Cancer

Sangiliyandi Gurunathan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Pharmacology & Pharmacy

Paclitaxel skin delivery by micelles-embedded Carbopol 940 hydrogel for local therapy of melanoma

Hongmei Xu et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Topical nanostructured lipid carrier gel of quercetin and resveratrol: Formulation, optimization, in vitro and ex vivo study for the treatment of skin cancer

Mohammad Imran et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Self-assembly of pH-sensitive micelles for enhanced delivery of doxorubicin to melanoma cells

Miaomiao Long et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

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Article Chemistry, Multidisciplinary

Anti-Melanoma Activity of Indomethacin Incorporated into Mesoporous Silica Nanoparticles

Natalia Helen Ferreira et al.

PHARMACEUTICAL RESEARCH (2020)

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Review Biotechnology & Applied Microbiology

Alginate-Based Platforms for Cancer-Targeted Drug Delivery

Lili He et al.

BIOMED RESEARCH INTERNATIONAL (2020)

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Article Oncology

The role and economics of immunotherapy in solid tumour management

Dominic Adam Worku et al.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2020)

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Review Pharmacology & Pharmacy

Transfersomes: A Promising Nanoencapsulation Technique for Transdermal Drug Delivery

Shakthi Apsara Thejani Opatha et al.

PHARMACEUTICS (2020)

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Article Pharmacology & Pharmacy

Tailoring of berberine loaded transniosomes for the management of skin cancer in mice

Dipak Kumar Gupta et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

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Article Multidisciplinary Sciences

Interaction of Ras Binding Domain (RBD) by chemotherapeutic zinc oxide nanoparticles: Progress towards RAS pathway protein interference

Elza Neelima Mathew et al.

PLOS ONE (2020)

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Article Multidisciplinary Sciences

Nano-MOFs as targeted drug delivery agents to combat antibiotic-resistant bacterial infections

Saleh A. Ahmed et al.

ROYAL SOCIETY OPEN SCIENCE (2020)

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Article Materials Science, Multidisciplinary

Cancer cell specific cytotoxic potential of the silver nanoparticles synthesized using the endophytic fungus, Penicillium citrinum CGJ-C2

Ananda Danagoudar et al.

MATERIALS TODAY COMMUNICATIONS (2020)

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Review Chemistry, Multidisciplinary

Therapeutic strategies and potential implications of silver nanoparticles in the management of skin cancer

Shaloam Dasari et al.

NANOTECHNOLOGY REVIEWS (2020)

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Article Nanoscience & Nanotechnology

In Vivo Evaluation of the Antitumor and Immunogenic Properties of Silver and Sodium Dichloroacetate Combination against Melanoma

Zaida Torres-Cavazos et al.

JOURNAL OF NANOMATERIALS (2020)

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Article Pharmacology & Pharmacy

The Design of Anionic Surfactant-Based Amino-Functionalized Mesoporous Silica Nanoparticles and their Application in Transdermal Drug Delivery

Aliyah Almomen et al.

PHARMACEUTICS (2020)

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Article Oncology

Protein kinase C inhibitor anchored BRD4 PROTAC PEGylated nanoliposomes for the treatment of vemurafenib-resistant melanoma

Yige Fu et al.

EXPERIMENTAL CELL RESEARCH (2020)

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Article Pharmacology & Pharmacy

Co-Delivery of Hispolon and Doxorubicin Liposomes Improves Efficacy Against Melanoma Cells

Ahmed Al Saqr et al.

AAPS PHARMSCITECH (2020)

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Article Engineering, Biomedical

Virus-like nanoparticle as a co-delivery system to enhance efficacy of CRISPR/Cas9-based cancer immunotherapy

Qi Liu et al.

BIOMATERIALS (2020)

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Article Materials Science, Biomaterials

Dissolving microneedles integrated with pH-responsive micelles containing AIEgen with ultra-photostability for enhancing melanoma photothermal therapy

Sihui Wei et al.

BIOMATERIALS SCIENCE (2020)

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Article Materials Science, Biomaterials

MWCNT-mediated combinatorial photothermal ablation and chemo-immunotherapy strategy for the treatment of melanoma

Xiaoxiao Wang et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Genetics & Heredity

Green way biosynthesis: Characterization, antimicrobial and anticancer activity of ZnO nanoparticles

E. Vidhya et al.

GENE REPORTS (2020)

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Article Pharmacology & Pharmacy

Improving STING Agonist Delivery for Cancer Immunotherapy Using Biodegradable Mesoporous Silica Nanoparticles

Kyung Soo Park et al.

ADVANCED THERAPEUTICS (2020)

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Review Medicine, General & Internal

Surgical Margin of Excision in Basal Cell Carcinoma: A Systematic Review of Literature

Sohail J. Quazi et al.

CUREUS JOURNAL OF MEDICAL SCIENCE (2020)

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Review Chemistry, Multidisciplinary

A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems

Yongtao Duan et al.

RSC ADVANCES (2020)

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Review Materials Science, Biomaterials

Zinc oxide nanoparticles for therapeutic purposes in cancer medicine

Nadine Wiesmann et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Materials Science, Biomaterials

Low-dose paclitaxel via hyaluronan-functionalized bovine serum albumin nanoparticulate assembly for metastatic melanoma treatment

Xue Chen et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Medicine, Research & Experimental

ZnO-based multifunctional nanocomposites to inhibit progression and metastasis of melanoma by eliciting antitumor immunity via immunogenic cell death

Yamin Zhang et al.

THERANOSTICS (2020)

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Article Medicine, Research & Experimental

Dissolving Microneedles with Spatiotemporally controlled pulsatile release Nanosystem for Synergistic Chemo-photothermal Therapy of Melanoma

Wanbing Qin et al.

THERANOSTICS (2020)

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Review Pharmacology & Pharmacy

Nanostructured Lipid Carriers: A Groundbreaking Approach for Transdermal Drug Delivery

Iti Chauhan et al.

ADVANCED PHARMACEUTICAL BULLETIN (2020)

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Article Engineering, Biomedical

Nanovaccine based on a protein-delivering dendrimer for effective antigen cross-presentation and cancer immunotherapy

Jun Xu et al.

BIOMATERIALS (2019)

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Article Oncology

Cutaneous Squamous Cell Carcinoma

Abigail Waldman et al.

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA (2019)

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Article Nanoscience & Nanotechnology

Starch-mediated synthesis of mono- and bimetallic silver/gold nanoparticles as antimicrobial and anticancer agents

Diana Lomeli-Marroquin et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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Article Pharmacology & Pharmacy

Optimization and in-vitro/in-vivo evaluation of doxorubicin-loaded chitosan-alginate nanoparticles using a melanoma mouse model

Krassimira Yoncheva et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Biochemistry & Molecular Biology

Inhibitory effect of black tea (Camellia sinensis) theaflavins and thearubigins against HCT 116 colon cancer cells and HT 460 lung cancer cells

Ali Imran et al.

JOURNAL OF FOOD BIOCHEMISTRY (2019)

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Review Chemistry, Multidisciplinary

Application of Solid Lipid Nanoparticles to Improve the Efficiency of Anticancer Drugs

Laura Bayon-Cordero et al.

NANOMATERIALS (2019)

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Article Biochemistry & Molecular Biology

Label-Free Fluorescent Poly(amidoamine) Dendrimer for Traceable and Controlled Drug Delivery

Guoying Wang et al.

BIOMACROMOLECULES (2019)

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Review Medicine, General & Internal

Progress in research on gold nanoparticles in cancer management

Jingwen Peng et al.

MEDICINE (2019)

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Article Biotechnology & Applied Microbiology

Silymarin-loaded nanostructured lipid carrier gel for the treatment of skin cancer

Babar Iqbal et al.

NANOMEDICINE (2019)

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Review Chemistry, Multidisciplinary

Lipid-Based Nanoparticles: Application and Recent Advances in Cancer Treatment

Beatriz Garcia-Pinel et al.

NANOMATERIALS (2019)

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Review Chemistry, Multidisciplinary

Gold Nanoparticles for Photothermal Cancer Therapy

Jeremy B. Vines et al.

FRONTIERS IN CHEMISTRY (2019)

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Article Oncology

Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients

Charles T. Lee et al.

CANCER (2019)

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Article Nanoscience & Nanotechnology

Size-dependent cellular uptake and localization profiles of silver nanoparticles

Meiyu Wu et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

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Review Pharmacology & Pharmacy

Strategizing biodegradable polymeric nanoparticles to cross the biological barriers for cancer targeting

Hira Choudhury et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2019)

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Article Cell Biology

Antiproliferative and Antitumour Effect of Nongenotoxic Silver Nanoparticles on Melanoma Models

Lucia M. Valenzuela-Salas et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

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Review Dermatology

Photodynamic therapy for solid tumors: A review of the literature

Rebecca L. Yanovsky et al.

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE (2019)

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Review Materials Science, Multidisciplinary

Dendrimer-entrapped gold nanoparticles as promising nanocarriers for anticancer therapeutics and imaging

Prashant Kesharwani et al.

PROGRESS IN MATERIALS SCIENCE (2019)

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Article Biotechnology & Applied Microbiology

NIR triggered glycosylated gold nanoshell as a photothermal agent on melanoma cancer cells

Samira Nouri et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

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Review Chemistry, Multidisciplinary

Designer Peptide and Protein Dendrimers: A Cross-Sectional Analysis

Rachit Sapra et al.

CHEMICAL REVIEWS (2019)

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Article Biochemistry & Molecular Biology

Verteporfin-loaded mesoporous silica nanoparticles inhibit mouse melanoma proliferation in vitro and in vivo

Nausicaa Clemente et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2019)

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Article Nanoscience & Nanotechnology

Supramolecular Insights into Domino Effects of Ag@ZnO-Induced Oxidative Stress in Melanoma Cancer Cells

Behnaz Ghaemi et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Multidisciplinary

Immune-triggered cancer treatment by intestinal lymphatic delivery of docetaxel-loaded nanoparticle

Kyoung Sub Kim et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Chemistry, Physical

Gold nanoparticles: New routes across old boundaries

Yogita Kumari et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2019)

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Article Pharmacology & Pharmacy

Betulin silver nanoparticles qualify as efficient antimelanoma agents in in vitro and in vivo studies

Corina Danciu et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

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Article Nanoscience & Nanotechnology

Multiwalled Carbon Nanotubes Prevent Tumor Metastasis Through Switching M2-Polarized Macrophages to M1 via TLR4 Activation

Lianlian Wu et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2019)

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Article Pharmacology & Pharmacy

Photodynamic therapy on skin melanoma and epidermoid carcinoma cells using conjugated 5-aminolevulinic acid with microbial synthesised silver nanoparticles

Aishwarya Shivashankarappa et al.

JOURNAL OF DRUG TARGETING (2019)

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Article Biochemistry & Molecular Biology

Proof of concept studies for siRNA delivery by nonionic surfactant vesicles: in vitro and in vivo evaluation of protein knockdown

Mohammad A. Obeid et al.

JOURNAL OF LIPOSOME RESEARCH (2019)

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Review Medicine, Research & Experimental

Gold Nanoparticles in Cancer Treatment

Krzysztof Sztandera et al.

MOLECULAR PHARMACEUTICS (2019)

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Article Chemistry, Multidisciplinary

Multicomponent access to novel proline/cyclized cysteine tethered monastrol conjugates as potential anticancer agents

M. Shaheer Malik et al.

JOURNAL OF SAUDI CHEMICAL SOCIETY (2019)

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Review Engineering, Biomedical

Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer

Tingting Li et al.

ACTA BIOMATERIALIA (2019)

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Review Immunology

Immunotherapy for skin cancer

Kelly G. Paulson et al.

INTERNATIONAL IMMUNOLOGY (2019)

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Article Medicine, Research & Experimental

Low Molecular Weight Heparin-Coated and Dendrimer-Based Core-Shell Nanoplatform with Enhanced Immune Activation and Multiple Anti-Metastatic Effects for Melanoma Treatment

Chunyu Xia et al.

THERANOSTICS (2019)

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Article Chemistry, Multidisciplinary

Transdermal delivery of small interfering RNAs with topically applied mesoporous silica nanoparticles for facile skin cancer treatment

Daniel Chin Shiuan Lio et al.

NANOSCALE (2019)

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Review Dermatology

Radiotherapy for Melanoma: More than DNA Damage

Susanne J. Rogers et al.

DERMATOLOGY RESEARCH AND PRACTICE (2019)

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Article Materials Science, Biomaterials

A peptide- modified solid lipid nanoparticle formulation of paclitaxel modulates immunity and outperforms dacarbazine in a murine melanoma model

Indranil Banerjee et al.

BIOMATERIALS SCIENCE (2019)

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Article Nanoscience & Nanotechnology

Hybrid Hydrogel Composed of Carboxymethylcellulose-Silver Nanoparticles-Doxorubicin for Anticancer and Antibacterial Therapies against Melanoma Skin Cancer Cells

Nadia S. V. Capanema et al.

ACS APPLIED NANO MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Multifunctional biomimetic nanoparticles loading baicalin for polarizing tumor-associated macrophages

Shulan Han et al.

NANOSCALE (2019)

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Review Biochemistry & Molecular Biology

Highlighted STAT3 as a potential drug target for cancer therapy

Haeri Lee et al.

BMB REPORTS (2019)

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Article Medicine, Research & Experimental

Synthesis and characterization of copper nanoparticles stabilized with Quisqualis indica extract: Evaluation of its cytotoxicity and apoptosis in B16F10 melanoma cells

Ria Mukhopadhyay et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

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Article Chemistry, Multidisciplinary

Advanced Inorganic Nanosystems for Skin Drug Delivery

E. Carazo et al.

CHEMICAL RECORD (2018)

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Article Biophysics

Photo-triggered destabilization of nanoscopic vehicles by dihydroindolizine for enhanced anticancer drug delivery in cervical carcinoma

Priya Singh et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2018)

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Review Pharmacology & Pharmacy

Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery

Prashant Kesharwani et al.

DRUG DISCOVERY TODAY (2018)

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Article Biochemistry & Molecular Biology

Solid Lipid Nanoparticles Carrying Temozolomide for Melanoma Treatment. Preliminary In Vitro and In Vivo Studies

Nausicaa Clemente et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

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Review Pharmacology & Pharmacy

Inorganic nanoparticles: A potential cancer therapy for human welfare

Arivalagan Pugazhendhi et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Article Dermatology

Cutaneous squamous cell carcinoma Incidence, risk factors, diagnosis, and staging

Syril Keena T. Que et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2018)

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Review Biochemistry & Molecular Biology

Liposomal Drug Delivery Systems and Anticancer Drugs

Temidayo O. B. Olusanya et al.

MOLECULES (2018)

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Article Nanoscience & Nanotechnology

Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem

Yujuan Zhang et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

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Article Nanoscience & Nanotechnology

Doxorubicin-loaded dendritic-Fe3O4 supramolecular nanoparticles for magnetic drug targeting and tumor regression in spheroid murine melanoma model

Saumya Nigam et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

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Article Chemistry, Multidisciplinary

Biodegradable multi-walled carbon nanotubes trigger anti-tumoral effects

E. Gonzalez-Lavado et al.

NANOSCALE (2018)

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Article Chemistry, Multidisciplinary

RGD-modified dihydrolipoamide dehydrogenase conjugated to titanium dioxide nanoparticles - switchable integrin-targeted photodynamic treatment of melanoma cells

Avraham Dayan et al.

RSC ADVANCES (2018)

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Article Biotechnology & Applied Microbiology

5-Fluorouracil ethosomes - skin deposition and melanoma permeation synergism with microwave

Nauman Rahim Khan et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

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Article Biotechnology & Applied Microbiology

Biogenesis of silver nanoparticles using leaf extract of Indigofera hirsuta L. and their potential biomedical applications (3-in-1 system)

Vasudeva Reddy Netala et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

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Article Pharmacology & Pharmacy

Editorial: Adverse Effects of Cancer Chemotherapy: Anything New to Improve Tolerance and Reduce Sequelae?

Kulmira Nurgali et al.

FRONTIERS IN PHARMACOLOGY (2018)

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Article Engineering, Biomedical

Micelles with ultralow critical micelle concentration as carriers for drug delivery

Yang Lu et al.

NATURE BIOMEDICAL ENGINEERING (2018)

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Article Chemistry, Multidisciplinary

Enhanced Transdermal Drug Delivery by Transfersome-Embedded Oligopeptide Hydrogel for Topical Chemotherapy of Melanoma

Tianyue Jiang et al.

ACS NANO (2018)

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Article Pharmacology & Pharmacy

Biotinylated PAMAM G3 dendrimer conjugated with celecoxib and/or Fmoc-L-Leucine and its cytotoxicity for normal and cancer human cell lines

Lukasz Uram et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

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Article Pharmacology & Pharmacy

Green synthesis of silver nanoparticles using Trapa natans extract and their anticancer activity against A431 human skin cancer cells

Mohaddeseh Mahmoudi Saber et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2018)

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Article Chemistry, Applied

Bovine serum albumin nanoparticles improve the antitumour activity of curcumin in a murine melanoma model

Luciana Erzinger Alves de Camargo et al.

JOURNAL OF MICROENCAPSULATION (2018)

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Article Chemistry, Multidisciplinary

Targeting myeloid regulators by paclitaxel-loaded enzymatically degradable nanocups

Seth C. Burkert et al.

NANOSCALE (2018)

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Article Chemistry, Multidisciplinary

Platinum nanoparticles: a non-toxic, effective and thermally stable alternative plasmonic material for cancer therapy and bioengineering

Akbar Samadi et al.

NANOSCALE (2018)

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Article Oncology

Not Only Redox: The Multifaceted Activity of Cerium Oxide Nanoparticles in Cancer Prevention and Therapy

Francesca Corsi et al.

FRONTIERS IN ONCOLOGY (2018)

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Article Pharmacology & Pharmacy

Coated microneedles mediated intradermal delivery of octaarginine/BRAF siRNA nanocomplexes for anti-melanoma treatment

Wenyi Ruan et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

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Review Genetics & Heredity

Advances in Carbon Nanotubes for Malignant Melanoma: A Chance for Treatment

Elidamar Nunes de Carvalho Lima et al.

MOLECULAR DIAGNOSIS & THERAPY (2018)

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Review Oncology

A systematic review of the cost and cost-effectiveness studies of immune checkpoint inhibitors

Vivek Verma et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)

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Article Pharmacology & Pharmacy

Novel Combination of Silver Nanoparticles and Carbon Nanotubes for Plasmonic Photo Thermal Therapy in Melanoma Cancer Model

Mohammad Ali Behnam et al.

ADVANCED PHARMACEUTICAL BULLETIN (2018)

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Article Ophthalmology

Single-walled carbon nanotube, multi-walled carbon nanotube and Fe2O3 nanoparticles induced mitochondria mediated apoptosis in melanoma cells

Parvaneh Naserzadeh et al.

CUTANEOUS AND OCULAR TOXICOLOGY (2018)

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Article Nanoscience & Nanotechnology

Photothermal therapy of melanoma tumor using multiwalled carbon nanotubes

Zahra Sobhani et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

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Article Nanoscience & Nanotechnology

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile

Pedram Rafiei et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

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Review Chemistry, Multidisciplinary

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

Philip Grossen et al.

JOURNAL OF CONTROLLED RELEASE (2017)

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Article Medicine, Research & Experimental

Zinc Oxide Nanoparticle-Poly I:C RNA Complexes: Implication as Therapeutics against Experimental Melanoma

Meghana Ramani et al.

MOLECULAR PHARMACEUTICS (2017)

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Article Nanoscience & Nanotechnology

Metallic copper nanoparticles induce. apoptosis in a. human skin melanoma. A-375 cell line

Ruchira Chakraborty et al.

NANOTECHNOLOGY (2017)

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Article Chemistry, Multidisciplinary

Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response

Jun Xie et al.

SMALL (2017)

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Article Chemistry, Multidisciplinary

Simulated Sunlight-Mediated Photodynamic Therapy for Melanoma Skin Cancer by Titanium-Dioxide-Nanoparticle-Gold-Nanocluster-Graphene Heterogeneous Nanocomposites

Yan Cheng et al.

SMALL (2017)

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Article Biotechnology & Applied Microbiology

Poly-lactic acid nanoparticles (PLA-NP) promote physiological modifications in lung epithelial cells and are internalized by clathrin-coated pits and lipid rafts

Camila Macedo da Luz et al.

JOURNAL OF NANOBIOTECHNOLOGY (2017)

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Article Chemistry, Multidisciplinary

Self-Assembled Vesicle-Carbon Nanotube Conjugate Formation through a Boronate-Diol Covalent Linkage

Soumik Dinda et al.

CHEMISTRY-A EUROPEAN JOURNAL (2017)

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Article Oncology

Solid lipid nanoparticles improve octyl gallate antimetastatic activity and ameliorate its renal and hepatic toxic effects

Clarissa A. S. Cordova et al.

ANTI-CANCER DRUGS (2017)

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Article Pharmacology & Pharmacy

Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy

Min Zhou et al.

DRUG DELIVERY (2017)

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Article Chemistry, Medicinal

An Integrin-Targeting RGDK-Tagged Nanocarrier: Anticancer Efficacy of Loaded Curcumin

Krishnendu Das et al.

CHEMMEDCHEM (2017)

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Review Engineering, Biomedical

Nanotechnology for the treatment of melanoma skin cancer

Lucas B. Naves et al.

PROGRESS IN BIOMATERIALS (2017)

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Article Biophysics

α-Tocopheryl linolenate solid lipid nanoparticles for the encapsulation, protection, and release of the omega-3 polyunsaturated fatty acid: in vitro anti-melanoma activity evaluation

Roberta Cassano et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

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Review Engineering, Biomedical

PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery

Duy Luong et al.

ACTA BIOMATERIALIA (2016)

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Article Engineering, Biomedical

Dual stimulation of antigen presenting cells using carbon nanotube-based vaccine delivery system for cancer immunotherapy

Hatem A. F. M. Hassan et al.

BIOMATERIALS (2016)

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Review Oncology

Therapeutic Approaches to RAS Mutation

Aaron J. Scott et al.

CANCER JOURNAL (2016)

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Article Pharmacology & Pharmacy

5-Fluorouracil shell-enriched solid lipid nanoparticles (SLN) for effective skin carcinoma treatment

Rasha A. Khallaf et al.

DRUG DELIVERY (2016)

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Article Chemistry, Medicinal

Topical delivery of paclitaxel for treatment of skin cancer

Rituraj Bharadwaj et al.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2016)

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Article Chemistry, Applied

Dermal delivery of doxorubicin-loaded solid lipid nanoparticles for the treatment of skin cancer

Ailar Tupal et al.

JOURNAL OF MICROENCAPSULATION (2016)

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Article Chemistry, Multidisciplinary

Effect of capping agents on the cytotoxicity of silver nanoparticles in human normal and cancer skin cell lines

Ponsawan Netchareonsirisuk et al.

JOURNAL OF NANOPARTICLE RESEARCH (2016)

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Review Chemistry, Applied

Stimuli-responsive mesoporous silica nanoparticles for cancer therapy: A review

Andre F. Moreira et al.

MICROPOROUS AND MESOPOROUS MATERIALS (2016)

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Review Oncology

Chemically induced skin carcinogenesis: Updates in experimental models (Review)

Monica Neagu et al.

ONCOLOGY REPORTS (2016)

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Article Spectroscopy

Biogenic terbium oxide nanoparticles as the vanguard against osteosarcoma

Sana Iram et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2016)

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Article Engineering, Biomedical

Multiwalled Carbon Nanotubes Inhibit Tumor Progression in a Mouse Model

Lorena Garcia-Hevia et al.

ADVANCED HEALTHCARE MATERIALS (2016)

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Review Plant Sciences

Hypericin in the Light and in the Dark: Two Sides of the Same Coin

Zuzana Jendzelovska et al.

FRONTIERS IN PLANT SCIENCE (2016)

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Article Health Care Sciences & Services

Bowen’s disease – a review of newer treatment options

Percy Lehmann

Therapeutics and Clinical Risk Management (2016)

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Article Engineering, Environmental

Pd nanoparticles supported on iron oxide nanorods for CO oxidation: Effect of preparation method

Abd El Rahman S. Khder et al.

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2016)

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Article Biochemistry & Molecular Biology

Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity

Milica Pesic et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2015)

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Review Oncology

Basal cell carcinoma of the skin (part 1): epidemiology, pathology and genetic syndromes

Tiago Ribeiro Correia de Sa et al.

FUTURE ONCOLOGY (2015)

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Review Medicine, Research & Experimental

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

Douglas Marvel et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

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Article Oncology

Five-Year Survival Rates for Treatment-Naive Patients With Advanced Melanoma Who Received Ipilimumab Plus Dacarbazine in a Phase III Trial

Michele Maio et al.

JOURNAL OF CLINICAL ONCOLOGY (2015)

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Article Medicine, General & Internal

Skin Cancer Epidemiology, Detection, and Management

Sumul Ashok Gandhi et al.

MEDICAL CLINICS OF NORTH AMERICA (2015)

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Article Pharmacology & Pharmacy

Fabrication and in vivo evaluation of Nelfinavir loaded PLGA nanoparticles for enhancing oral bioavailability and therapeutic effect

D. Nagasamy Venkatesh et al.

SAUDI PHARMACEUTICAL JOURNAL (2015)

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Article Biochemistry & Molecular Biology

Cerium Oxide Nanoparticles Induce Oxidative Stress and Genotoxicity in Human Skin Melanoma Cells

Daoud Ali et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2015)

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Review Pharmacology & Pharmacy

Cisplatin in cancer therapy: Molecular mechanisms of action

Shaloam Dasari et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2014)

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Article Nanoscience & Nanotechnology

Effect of Iontophoresis on Topical Delivery of Doxorubicin-Loaded Solid Lipid Nanoparticles

Stephania F. Taveira et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)

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Article Chemistry, Multidisciplinary

Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression

Sanjun Shi et al.

JOURNAL OF CONTROLLED RELEASE (2014)

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Letter Dermatology

Patient-reported outcomes of electrodessication and curettage for treatment of nonmelanoma skin cancer

Elyse Galles et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2014)

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Review Biotechnology & Applied Microbiology

Cerium oxide nanoparticles in cancer

Ying Gao et al.

ONCOTARGETS AND THERAPY (2014)

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Article Biochemistry & Molecular Biology

Downregulation of Tumor Growth and Invasion by Redox-Active Nanoparticles

Lirija Alili et al.

ANTIOXIDANTS & REDOX SIGNALING (2013)

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Review Chemistry, Multidisciplinary

Synthesis of mesoporous silica nanoparticles

Si-Han Wu et al.

CHEMICAL SOCIETY REVIEWS (2013)

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Article Oncology

Nanoemulsions and nanoparticles for non-melanoma skin cancer: effects of lipid materials

P. Severino et al.

CLINICAL & TRANSLATIONAL ONCOLOGY (2013)

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Article Dermatology

Chemotherapy in the management of advanced cutaneous malignant melanoma

Jason J. Luke et al.

CLINICS IN DERMATOLOGY (2013)

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Review Biochemistry & Molecular Biology

UV Radiation and the Skin

John D'Orazio et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

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Editorial Material Dermatology

Dacarbazine in Melanoma: From a Chemotherapeutic Drug to an Immunomodulating Agent

Selma Ugurel et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)

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Review Nanoscience & Nanotechnology

Polymeric nanoparticles-based topical delivery systems for the treatment of dermatological diseases

Zheng Zhang et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2013)

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Review Oncology

A Comprehensive Survey of Ras Mutations in Cancer

Ian A. Prior et al.

CANCER RESEARCH (2012)

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Article Dermatology

The Pathology of Melanoma

Clay J. Cockerell

DERMATOLOGIC CLINICS (2012)

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Review Medicine, Research & Experimental

Basal cell carcinoma - molecular biology and potential new therapies

Maria Kasper et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

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Review Chemistry, Multidisciplinary

Doxil® - The first FDA-approved nano-drug: Lessons learned

Yechezkel (Chezy) Barenholz

JOURNAL OF CONTROLLED RELEASE (2012)

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Review Oncology

A brief history of melanoma: from mummies to mutations

Vito W. Rebecca et al.

MELANOMA RESEARCH (2012)

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Review Pharmacology & Pharmacy

Carbon Nanotubes in Cancer Therapy and Drug Delivery

Abdelbary M. A. Elhissi et al.

JOURNAL OF DRUG DELIVERY (2012)

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Review Cell Biology

Hedgehog signaling in skin cancers

Chengxin Li et al.

CELLULAR SIGNALLING (2011)

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Review Chemistry, Physical

Overview of Cell Death Mechanisms Induced by Rose Bengal Acetate-Photodynamic Therapy

Elisa Panzarini et al.

INTERNATIONAL JOURNAL OF PHOTOENERGY (2011)

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Article Chemistry, Multidisciplinary

Structural and catalytic properties of ZnO and Al2O3 nanostructures loaded with metal nanoparticles

Osama A. Fouad et al.

JOURNAL OF NANOPARTICLE RESEARCH (2011)

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Article Dermatology

Surgical excision of skin cancer: the importance of training

P. Salmon et al.

BRITISH JOURNAL OF DERMATOLOGY (2010)

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Review Oncology

Anticancer function of polyinosinic-polycytidylic acid

Yu-Sheng Cheng et al.

CANCER BIOLOGY & THERAPY (2010)

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Article Chemistry, Applied

Carbon nanotubes for transdermal drug delivery

Ismail Tuncer Degim et al.

JOURNAL OF MICROENCAPSULATION (2010)

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Article Polymer Science

Silica Reinforced Organic-Inorganic Hybrid Polyurethane Nanocomposites From Sustainable Resource

Deewan Akram et al.

MACROMOLECULAR CHEMISTRY AND PHYSICS (2010)

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Review Chemistry, Physical

Reverse micelles from amphiphilic branched polymers

Marie-Christine Jones et al.

SOFT MATTER (2010)

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Article Biochemistry & Molecular Biology

Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer

Shyh-Dar Li et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

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Article Oncology

Long-term follow-up of topical 5-aminolaevulinic acid photodynamic therapy diode laser single session for non-melanoma skin cancer

C. S. Souza et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2009)

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Article Chemistry, Multidisciplinary

Effect of Nb and Sc doping on the phase transformation of sol-gel processed TiO2 nanoparticles

A. Ahmad et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2008)

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Article Medicine, Research & Experimental

Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: Enhanced efficacy and intratumoral transport capability

Renu Singh Dhanikula et al.

MOLECULAR PHARMACEUTICS (2008)

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Article Dermatology

Epidemiology and aetiology of basal cell carcinoma

J. Roewert-Huber et al.

BRITISH JOURNAL OF DERMATOLOGY (2007)

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Article Medicine, Research & Experimental

Paclitaxel albumin-bound particles (abraxaneTM) in combination with bevacizumab with or without gemcitabine:: Early experience at the University of Miami/Braman Family Breast Cancer Institute

Christopher Lobo et al.

BIOMEDICINE & PHARMACOTHERAPY (2007)

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Review Dermatology

Basal cell carcinoma: Review of epidemiology, pathogenesis, and associated risk factors

William Lear et al.

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2007)

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Review Oncology

Skin cancer and immunosuppression

G Gerlini et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2005)

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Article Dermatology

Histopathology of cutaneous squamous cell carcinoma and its variants

CL Kane et al.

SEMINARS IN CUTANEOUS MEDICINE AND SURGERY (2004)

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Article Dermatology

Cryosurgery for skin cancer: 30-year experience and cure rates

EG Kuflik

DERMATOLOGIC SURGERY (2004)

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Review Medicine, General & Internal

Basal cell carcinoma

CSM Wong et al.

BMJ-BRITISH MEDICAL JOURNAL (2003)

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