Electrochemical detection of tyrosine with casting electrode with carbon black and graphene oxide co-doped

This study investigated the performance of carbon-based carbon black (CB) and graphene oxide (GO) co-doped electrodes for electrochemical testing and analyzed their respective contributions to electrochemical perfor-mance. In this study, a CB-GO/CP two-layer electrode system was constructed on the surface of a hydrophilic carbon paper (CP) for the electrochemical detection of tyrosine (Tyr). The fabricated electrochemical electrode significantly increases the active area, and as a convenient and low-cost method of electrode fabrication, it significantly simplifies the electrode manufacturing process, eliminating the steps of electrode pretreatment, in situ modification, and post-treatment. Electrochemical test results demonstrate that the sensitivity to Tyr is [1.07 x 10-1 mu A/mu M cm2], Limit of detection (LOD) [100 mu M], and linear ranges [0.1-2 mM]. It also has one-week electrode stability and good repeatability. Scanning electron microscopy and Raman spectra of the CB-GO/CP electrodes show that GO and CB form a solid structure through the combination of van der Waals force, adsorption force, and CP substrate. A convenient CB-GO co-doped electrochemical electrode for Tyr detection will play a significant role in biomedical and civilian detection fields.

Automated summary

This study examined the performance of carbon black and graphene oxide co-doped electrodes and analyzed their contributions to electrochemical performance. A two-layer electrode system was fabricated on a hydrophilic carbon paper surface for the electrochemical detection of tyrosine. The electrode showed increased active area, simplified fabrication process, improved stability and repeatability. The combination of carbon black and graphene oxide formed a solid structure through van der Waals force, adsorption force, and carbon paper substrate. This co-doped electrode will play a significant role in biomedical and civilian detection fields.