4.6 Letter

Balancing the medical and social needs of children during the COVID-19 pandemic

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Letter Medicine, General & Internal

Balancing the medical and social needs of children during the COVID-19 pandemic

Zoe Hyde

MEDICAL JOURNAL OF AUSTRALIA (2023)

Article Infectious Diseases

Persistent symptoms following SARS-CoV-2 infection amongst children and young people: A meta-analysis of controlled and uncontrolled studies

S. A. Behnood et al.

Summary: There is conflicting data on the long-term impact of SARS-CoV-2 infection in children and young people. This study assessed the evidence on long-term post-COVID symptoms in this population, including prevalence, risk factors, type, and duration. The findings suggest that the frequency of most reported persistent symptoms is similar in COVID-positive cases and controls.

JOURNAL OF INFECTION (2022)

Article Pediatrics

Long COVID (post-COVID-19 condition) in children: a modified Delphi process

Terence Stephenson et al.

Summary: The objective of this study was to establish a research definition for 'Long COVID (post-COVID-19 condition)' in children and young people (CYP) to enable comparison of research studies. A three-phase online Delphi process and a consensus meeting were conducted. The research definition proposed includes a minimum duration of 12 weeks of persisting physical symptoms after initial testing, impacting everyday functioning and not explained by an alternative diagnosis, in young people with a history of confirmed SARS-CoV-2 infection. This is the first research definition of Long COVID in CYP and aligns with the clinical case definition proposed by the WHO.

ARCHIVES OF DISEASE IN CHILDHOOD (2022)

Review Immunology

The Challenge of Studying Long COVID: An Updated Review

Petra Zimmermann et al.

Summary: Accurately determining the risk of long COVID is challenging, especially in children and adolescents. Distinguishing symptoms related to long-term SARS-CoV-2 infection from pandemic-related symptoms is difficult. More robust data is needed to inform policy decisions.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2022)

Editorial Material Medicine, General & Internal

Balancing the medical and social needs of children during the COVID-19 pandemic

Keith Grimwood et al.

MEDICAL JOURNAL OF AUSTRALIA (2022)

Review Pediatrics

Prevalence and clinical presentation of long COVID in children: a systematic review

Roberta Pellegrino et al.

Summary: This systematic literature review summarizes the evidence of long COVID in children and adolescents, finding that the evidence is limited, heterogeneous, and based on low-quality studies. The prevalence of long COVID varies greatly, with a wide range of symptoms reported. Differentiating long COVID symptoms from the consequences of lockdown measures is challenging. High-quality studies, including controlled clinical studies and investigations into the impact of new variants, are needed for an objective analysis and proper allocation of healthcare resources for long COVID in children.

EUROPEAN JOURNAL OF PEDIATRICS (2022)