Electrospun bioactive tertiary glass nanoparticles-containing silica/gelatin/polyethylene oxide hybrid membranes for potential dental bone tissue engineering applications

Silica (SiO2)/gelatin (G)/polyethylene oxide (PEO) hybrid membranes with maximized gelatin and bioactive glass nanoparticles (NpBG) contents were produced by electrospinning using water as main solvent. The membranes obtained from the precursor 80 %SiO2/10 %G/8%PEO/2%NpBG were bioactive, non-toxic and showed enhanced ability for osteogenic differentiation, demonstrating their potential for dental tissue engi-neering applications.

Automated summary

Silica/gelatin/polyethylene oxide hybrid membranes with maximized gelatin and bioactive glass nanoparticles contents were produced by electrospinning using water as main solvent. The membranes obtained from the precursor showed bioactive, non-toxic and enhanced ability for osteogenic differentiation, demonstrating their potential for dental tissue engineering applications.