4.6 Article

Cu-MXene: A potential biocide for the next-generation biomedical application

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MATERIALS CHEMISTRY AND PHYSICS
卷 294, 期 -, 页码 -

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ELSEVIER SCIENCE SA
DOI: 10.1016/j.matchemphys.2022.127029

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MXene; Cu; Antibacterial activity; Biomedical; Antibiotics; Ceramic; Biocompatibility

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Bacterial resistance in humans has led to infectious diseases, necessitating the development of new antibacterial materials. The synthesized MXene and Cu-MXene materials showed high biocompatibility with erythrocyte cells and demonstrated excellent antibacterial activity against Gram-negative and Gram-positive bacterial strains. These materials can be safely used in biomedical applications.
Bacterial resistance in humans led to infectious diseases, one of the global health concerns. Therefore, developing newer biocidal material that combats such associated issues with existing antibiotics molecules is needed. In this aspect, the present study focuses on synthesizing the MXene and Cu-MXene materials for efficient antibacterial activity. The prepared MXene and Cu-MXene materials showed high biocompatibility against erythrocyte cells. The Cu-MXene materials showed superior antibacterial activity against Gram-negative (Escherichia coli (E. coli)) and Gram-positive (Staphylococcus aureus (S. aureus)) bacterial strains. It was observed that the prepared Cu-MXene materials had an intermediate antibiotic activity with high biocompatibility. Moreover, incorporating Cu within the inter-layered spacing of MXene might enhance the antibacterial activity. Therefore, the prepared MXene and Cu-MXene materials can be used against bacterial strains and safely in biomedical applications.

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