Antibacterial Mechanism of Chitosan-Gentamicin and Its Effect on the Intestinal Flora of Litopenaeus vannamei Infected with Vibrio parahaemolyticus

Article Chemistry, Applied

Dextran and peptide-based pH-sensitive hydrogel boosts healing process in multidrug-resistant bacteria-infected wounds

Siwen Wu et al.

Summary: We have developed a dual functional hydrogel that can kill multidrug-resistant bacteria and promote scarless wound healing.

CARBOHYDRATE POLYMERS (2022)

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Article Fisheries

Vibrio parahaemolyticus alters the community composition and function of intestinal microbiota in Pacific white shrimp, Penaeus vannamei

Xue Zhang et al.

Summary: Homeostasis of intestinal microbiota is crucial to host health, and pathogen invasion leads to dynamic changes in gut microbes. Vibrio parahaemolyticus is an important pathogen of Pacific white shrimp, causing high mortality. The TJA114 strain lacks the pir gene but showed strong pathogenicity, altering bacterial composition in shrimp gut. Metabolites involved in various pathways were identified, providing new insights into vibriosis pathogenesis in shrimp.

AQUACULTURE (2021)

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Article Chemistry, Applied

Therapeutic effect and immune mechanism of chitosan-gentamicin conjugate on Pacific white shrimp (Litopenaeus vannamei) infected with Vibrio parahaemolyticus

Fengyan Liang et al.

Summary: The chitosan-gentamicin conjugate (CS-GT) has been shown to enhance the immune response and disease resistance of Litopenaeus vannamei against Vibrio parahaemolyticus, possibly by stimulating lysosomal phagocytosis of pathogens.

CARBOHYDRATE POLYMERS (2021)

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Article Biochemistry & Molecular Biology

Interaction of sulfated polysaccharides with intestinal Bacteroidales plays an important role in its biological activities

Xiaona Sun et al.

Summary: This study found that sulfated polysaccharides from pacific abalone can alter the gut microbiota structure and increase relative abundances of certain Bacteroidales members, indicating the important role of intestinal Bacteroidales in the bioactivities of AGSP. Additionally, there is an AGSP utilization network among Bacteroidales species, which influences the anti-inflammatory activity and cytotoxicity of AGSP.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Biotechnology & Applied Microbiology

Facile green synthesis of copper oxide nanoparticles for the eradication of multidrug resistant Klebsiella pneumonia and Helicobacter pylori biofilms

Minha Naseer et al.

Summary: This study successfully synthesized copper oxide nanoparticles and confirmed their antibacterial activity against antibiotic-resistant strains, particularly Klebsiella pneumonia and Helicobacter pylori. The nanoparticles derived from Cassia fistula showed stronger inhibition of biofilm formation compared to those from Melia azedarach.

INTERNATIONAL BIODETERIORATION & BIODEGRADATION (2021)

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Article Environmental Sciences

Hepatopancreatic transcriptome analysis and humoral immune factor assays in red claw crayfish (Cherax quadricarinatus) provide insight into innate immunomodulation under Vibrio parahaemolyticus infection

Duanduan Chen et al.

Summary: The red claw crayfish is an economically and nutritionally important species. Infection by Vibrio parahaemolyticus caused hepatopancreas injury in the crayfish and changes in immune enzyme activity over time. Transcriptome analysis identified differentially expressed genes in susceptible and normal animals, and GO and KEGG analyses revealed immune-related pathways influenced by the infection.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021)

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Article Microbiology

LuxQ-LuxU-LuxO pathway regulates biofilm formation by Vibrio parahaemolyticus

Min Liu et al.

Summary: LuxQ, LuxU, and LuxO are demonstrated to be essential for controlling biofilm formation by Vibrio parahaemolyticus and function in the same signaling pathway. These proteins regulate biofilm formation by phosphorylating conserved residues and controlling the expression of cpsQ and cps loci.

MICROBIOLOGICAL RESEARCH (2021)

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Article Engineering, Environmental

Elastic, super-hydrophobic and biodegradable chitosan sponges fabricated for oil/water separation

Fengyan Liang et al.

Summary: The study fabricated a multi-network chitosan-based sponge with excellent elasticity and adsorption performance, characterized by various analytical techniques. The sponge showed good separation efficiency and magnetic recyclability even after multiple surface functionalizations.

JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING (2021)

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Article Fisheries